Ensembl ID ENSG00000109534 Gene ID 54433 Accession 14264
Gene Symbol GAR1 Alias NOLA1 Full Name GAR1 ribonucleoprotein
Position 4 : 109815510 - 109824740 Length 9231 bases Strand Plus strand
Status Confidence Main interacting RNAssnoRNARBP type Canonical_RBPs
Summary This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p. Two splice variants have been found for this gene. [provided by RefSeq, Jul 2008]

ENSG00000109534 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000109534 GAR1 0.77 1.08e-18 COAD
ENSG00000109534 GAR1 0.75 2.39e-22 KICH
ENSG00000109534 GAR1 0.53 1.46e-11 LUSC
ENSG00000109534 GAR1 0.51 1.09e-18 PRAD
ENSG00000109534 GAR1 0.68 2.42e-14 UCEC
ENSG00000109534 GAR1 0.53 2.04e-14 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000109534 GAR1 tumor 28666010
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000109534 GAR1 SARC 0.0068 high
ENSG00000109534 GAR1 STAD 0.016 low
ENSG00000109534 GAR1 PAAD 0.026 high
ENSG00000109534 GAR1 UCEC 0.02 high
ENSG00000109534 GAR1 ACC 0.025 high
ENSG00000109534 GAR1 HNSC 0.011 high
ENSG00000109534 GAR1 READ 0.00012 low
ENSG00000109534 GAR1 KICH 0.031 high
ENSG00000109534 GAR1 LUAD 0.00028 high
ENSG00000109534 GAR1 THYM 0.014 low
ENSG00000109534 GAR1 BRCA 0.013 low
ENSG00000109534 GAR1 OV 0.0066 low
ENSG00000109534 GAR1 DLBC 0.032 low
ENSG00000109534 GAR1 PRAD 0.0019 high
ENSG00000109534 GAR1 BLCA 7e-04 low
ENSG00000109534 GAR1 LAML 0.049 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000109534 GAR1 LIHC Del 1.994356 0.085734 0.542726 0.456757
ENSG00000109534 GAR1 UCEC Del 0.650986 0.046801 0.437267 0.205937
ENSG00000109534 GAR1 OV Del 5.767307 0.255797 0.631217 0.689119