Ensembl ID ENSG00000109475 Gene ID 6164 Accession 10340
Gene Symbol RPL34 Alias L34;eL34 Full Name ribosomal protein L34
Position 4 : 108620569 - 108630412 Length 9844 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L34E family of ribosomal proteins. It is located in the cytoplasm. This gene originally was thought to be located at 17q21, but it has been mapped to 4q. Overexpression of this gene has been observed in some cancer cells. Alternative splicing results in multiple transcript variants, all encoding the same isoform. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Feb 2016]

ENSG00000109475 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000109475 RPL34 0.67 2.76e-17 KIRC
ENSG00000109475 RPL34 -0.5 2.02e-17 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000109475 RPL34 tumor 26237576
ENSG00000109475 RPL34 gastric cancer 26323242
ENSG00000109475 RPL34 non-small cell lung cancer 26526135
ENSG00000109475 RPL34 tumor 27845896
ENSG00000109475 RPL34 gastric cancer 27883047
ENSG00000109475 RPL34 Esophageal Cancer 28109079
ENSG00000109475 RPL34 cancers 30105457
ENSG00000109475 RPL34 cancers 30216512
ENSG00000109475 RPL34 esophageal cancer 31574377
ENSG00000109475 RPL34 papillary thyroid cancer 31587286
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000109475 RPL34 MESO 0.0073 low
ENSG00000109475 RPL34 SARC 0.034 high
ENSG00000109475 RPL34 CHOL 0.021 high
ENSG00000109475 RPL34 UVM 0.017 low
ENSG00000109475 RPL34 READ 0.021 high
ENSG00000109475 RPL34 BRCA 0.014 low
ENSG00000109475 RPL34 OV 0.0089 low
ENSG00000109475 RPL34 TGCT 0.0081 low
ENSG00000109475 RPL34 BLCA 0.013 low
ENSG00000109475 RPL34 LAML 0.022 low
ENSG00000109475 RPL34 SKCM 0.039 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000109475 RPL34 LIHC Del 2.356553 0.090416 0.544721 0.459459
ENSG00000109475 RPL34 OV Del 6.868709 0.268325 0.633880 0.699482