Ensembl ID ENSG00000108826 Gene ID 51264 Accession 14483
Gene Symbol MRPL27 Alias L27mt;bL27m Full Name mitochondrial ribosomal protein L27
Position 17 : 50367857 - 50373207 Length 5351 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

ENSG00000108826 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000108826 MRPL27 0.81 7.95e-23 BRCA
ENSG00000108826 MRPL27 0.57 2.90e-12 LUSC
ENSG00000108826 MRPL27 0.86 1.83e-11 UCEC
ENSG00000108826 MRPL27 0.58 3.90e-12 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000108826 MRPL27 STAD 0.041 high
ENSG00000108826 MRPL27 CHOL 0.0022 high
ENSG00000108826 MRPL27 UVM 0.00049 high
ENSG00000108826 MRPL27 PAAD 0.027 low
ENSG00000108826 MRPL27 THCA 0.024 low
ENSG00000108826 MRPL27 ACC 0.019 high
ENSG00000108826 MRPL27 HNSC 0.028 high
ENSG00000108826 MRPL27 KICH 0.0031 high
ENSG00000108826 MRPL27 LUAD 0.028 high
ENSG00000108826 MRPL27 BRCA 0.05 low
ENSG00000108826 MRPL27 OV 0.012 low
ENSG00000108826 MRPL27 KIRC 0.0014 high
ENSG00000108826 MRPL27 BLCA 0.00027 low
ENSG00000108826 MRPL27 LAML 0.029 high
ENSG00000108826 MRPL27 GBM 0.012 high
ENSG00000108826 MRPL27 SKCM 0.0018 high
ENSG00000108826 MRPL27 CESC 0.0058 low
ENSG00000108826 MRPL27 LIHC 0.045 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000108826 MRPL27 SKCM Amp 1.467818 0.145692 0.519170 0.277929
ENSG00000108826 MRPL27 BRCA Amp 40.881861 0.492674 0.941891 0.320370