Ensembl ID ENSG00000108179 Gene ID 10105 Accession 9259
Gene Symbol PPIF Alias CYP3;CypD;CyP-M;Cyp-D Full Name peptidylprolyl isomerase F
Position 10 : 79347469 - 79355334 Length 7866 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008]

ENSG00000108179 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000108179 PPIF 0.87 1.08e-20 BRCA
ENSG00000108179 PPIF 1.59 8.04e-36 KICH
ENSG00000108179 PPIF 1.81 9.24e-61 LUSC
ENSG00000108179 PPIF -0.7 5.56e-12 LIHC
ENSG00000108179 PPIF 1.57 7.77e-31 UCEC
ENSG00000108179 PPIF 1.08 1.73e-32 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000108179 PPIF cancer 10741504
ENSG00000108179 PPIF breast cancer 11807954
ENSG00000108179 PPIF tumors of the breast 14729611
ENSG00000108179 PPIF tumour 15800627
ENSG00000108179 PPIF tumor 16376584
ENSG00000108179 PPIF cancer 16551620
ENSG00000108179 PPIF colon cancer 18056990
ENSG00000108179 PPIF cancer 19187006
ENSG00000108179 PPIF tumors 19228691
ENSG00000108179 PPIF tumor 19648961
ENSG00000108179 PPIF tumor 19942270
ENSG00000108179 PPIF tumor 20080742
ENSG00000108179 PPIF tumors 20978188
ENSG00000108179 PPIF tumour 21285984
ENSG00000108179 PPIF tumor 21555789
ENSG00000108179 PPIF breast cancer 22702493
ENSG00000108179 PPIF liver cancer 22869602
ENSG00000108179 PPIF tumor 23303179
ENSG00000108179 PPIF tumor 23386998
ENSG00000108179 PPIF tumors 23483560
ENSG00000108179 PPIF tumor 23583382
ENSG00000108179 PPIF cancer 23596421
ENSG00000108179 PPIF cancer 23598413
ENSG00000108179 PPIF pancreatic cancer 23845906
ENSG00000108179 PPIF tumor 24113185
ENSG00000108179 PPIF lung cancer 24343341
ENSG00000108179 PPIF cancer 24603329
ENSG00000108179 PPIF pancreatic cancer 24732633
ENSG00000108179 PPIF prostate cancer 24946211
ENSG00000108179 PPIF lung cancer 25201730
ENSG00000108179 PPIF tumor 25454774
ENSG00000108179 PPIF breast cancer 25576381
ENSG00000108179 PPIF tumor 25650317
ENSG00000108179 PPIF tumour 25728038
ENSG00000108179 PPIF cancer 25879199
ENSG00000108179 PPIF tumor 25936818
ENSG00000108179 PPIF breast cancer 25971350
ENSG00000108179 PPIF pancreatic cancer 26084607
ENSG00000108179 PPIF bladder cancer 26198749
ENSG00000108179 PPIF ovarian cancer 26228528
ENSG00000108179 PPIF gastric cancer 26388407
ENSG00000108179 PPIF tumor 26973251
ENSG00000108179 PPIF cancer 26975474
ENSG00000108179 PPIF cancer 27171435
ENSG00000108179 PPIF cancer 27658776
ENSG00000108179 PPIF tumor 27759562
ENSG00000108179 PPIF tumour 27811014
ENSG00000108179 PPIF liver cancer 28363167
ENSG00000108179 PPIF HNSCC 28881606
ENSG00000108179 PPIF tumor 28922540
ENSG00000108179 PPIF cancer 28986541
ENSG00000108179 PPIF cancer 29302888
ENSG00000108179 PPIF colon cancer 29374515
ENSG00000108179 PPIF cancer 30558250
ENSG00000108179 PPIF breast cancer 30662615
ENSG00000108179 PPIF tumor 31601784
ENSG00000108179 PPIF tumors 8869826
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000108179 PPIF MESO 0.0024 low
ENSG00000108179 PPIF SARC 0.023 high
ENSG00000108179 PPIF CHOL 0.014 high
ENSG00000108179 PPIF UCEC 0.0011 low
ENSG00000108179 PPIF THCA 0.002 high
ENSG00000108179 PPIF ACC 0.047 high
ENSG00000108179 PPIF LUSC 0.048 low
ENSG00000108179 PPIF HNSC 0.0042 high
ENSG00000108179 PPIF KICH 0.0074 low
ENSG00000108179 PPIF LUAD 0.0022 high
ENSG00000108179 PPIF PCPG 0.0067 low
ENSG00000108179 PPIF THYM 0.00053 high
ENSG00000108179 PPIF COAD 0.038 low
ENSG00000108179 PPIF ESCA 0.0019 high
ENSG00000108179 PPIF DLBC 0.033 low
ENSG00000108179 PPIF KIRC 0.00071 high
ENSG00000108179 PPIF PRAD 0.0062 high
ENSG00000108179 PPIF BLCA 0.038 low
ENSG00000108179 PPIF SKCM 0.0073 high
ENSG00000108179 PPIF CESC 0.029 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000108179 PPIF READ Amp 0.860215 0.131898 1.306604 0.066667
ENSG00000108179 PPIF UCS Amp 1.060248 0.552327 0.884707 0.428571
ENSG00000108179 PPIF THCA Del 1.956122 0.014971 0.503648 0.022044
ENSG00000108179 PPIF BRCA Amp 4.108827 0.200413 0.781616 0.138889
ENSG00000108179 PPIF STAD Amp 1.709658 0.162085 0.574129 0.185941
ENSG00000108179 PPIF UCEC Amp 4.906684 0.181033 0.759542 0.244898
ENSG00000108179 PPIF UCEC Del 0.814433 0.049211 0.514274 0.092764