Ensembl ID ENSG00000108179 Gene ID 10105 Accession 9259
Gene Symbol PPIF Alias CYP3;CypD;CyP-M;Cyp-D Full Name peptidylprolyl isomerase F
Position 10 : 79347469 - 79355334 Length 7866 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008]

ENSG00000108179 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000108179 0.87 1.08e-20 BRCA
ENSG00000108179 1.59 8.04e-36 KICH
ENSG00000108179 1.81 9.24e-61 LUSC
ENSG00000108179 -0.7 5.56e-12 LIHC
ENSG00000108179 1.57 7.77e-31 UCEC
ENSG00000108179 1.08 1.73e-32 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000108179 cancer 10741504
ENSG00000108179 breast cancer 11807954
ENSG00000108179 tumors of the breast 14729611
ENSG00000108179 tumour 15800627
ENSG00000108179 tumor 16376584
ENSG00000108179 cancer 16551620
ENSG00000108179 colon cancer 18056990
ENSG00000108179 cancer 19187006
ENSG00000108179 tumors 19228691
ENSG00000108179 tumor 19648961
ENSG00000108179 tumor 19942270
ENSG00000108179 tumor 20080742
ENSG00000108179 tumors 20978188
ENSG00000108179 tumour 21285984
ENSG00000108179 tumor 21555789
ENSG00000108179 breast cancer 22702493
ENSG00000108179 liver cancer 22869602
ENSG00000108179 tumor 23303179
ENSG00000108179 tumor 23386998
ENSG00000108179 tumors 23483560
ENSG00000108179 tumor 23583382
ENSG00000108179 cancer 23596421
ENSG00000108179 cancer 23598413
ENSG00000108179 pancreatic cancer 23845906
ENSG00000108179 tumor 24113185
ENSG00000108179 lung cancer 24343341
ENSG00000108179 cancer 24603329
ENSG00000108179 pancreatic cancer 24732633
ENSG00000108179 prostate cancer 24946211
ENSG00000108179 lung cancer 25201730
ENSG00000108179 tumor 25454774
ENSG00000108179 breast cancer 25576381
ENSG00000108179 tumor 25650317
ENSG00000108179 tumour 25728038
ENSG00000108179 cancer 25879199
ENSG00000108179 tumor 25936818
ENSG00000108179 breast cancer 25971350
ENSG00000108179 pancreatic cancer 26084607
ENSG00000108179 bladder cancer 26198749
ENSG00000108179 ovarian cancer 26228528
ENSG00000108179 gastric cancer 26388407
ENSG00000108179 tumor 26973251
ENSG00000108179 cancer 26975474
ENSG00000108179 cancer 27171435
ENSG00000108179 cancer 27658776
ENSG00000108179 tumor 27759562
ENSG00000108179 tumour 27811014
ENSG00000108179 liver cancer 28363167
ENSG00000108179 HNSCC 28881606
ENSG00000108179 tumor 28922540
ENSG00000108179 cancer 28986541
ENSG00000108179 cancer 29302888
ENSG00000108179 colon cancer 29374515
ENSG00000108179 cancer 30558250
ENSG00000108179 breast cancer 30662615
ENSG00000108179 tumor 31601784
ENSG00000108179 tumors 8869826
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000108179 MESO 0.0024 low
ENSG00000108179 SARC 0.023 high
ENSG00000108179 CHOL 0.014 high
ENSG00000108179 UCEC 0.0011 low
ENSG00000108179 THCA 0.002 high
ENSG00000108179 ACC 0.047 high
ENSG00000108179 LUSC 0.048 low
ENSG00000108179 HNSC 0.0042 high
ENSG00000108179 KICH 0.0074 low
ENSG00000108179 LUAD 0.0022 high
ENSG00000108179 PCPG 0.0067 low
ENSG00000108179 THYM 0.00053 high
ENSG00000108179 COAD 0.038 low
ENSG00000108179 ESCA 0.0019 high
ENSG00000108179 DLBC 0.033 low
ENSG00000108179 KIRC 0.00071 high
ENSG00000108179 PRAD 0.0062 high
ENSG00000108179 BLCA 0.038 low
ENSG00000108179 SKCM 0.0073 high
ENSG00000108179 CESC 0.029 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000108179 READ Amp 0.860215 0.131898 1.306604 0.066667
ENSG00000108179 UCS Amp 1.060248 0.552327 0.884707 0.428571
ENSG00000108179 THCA Del 1.956122 0.014971 0.503648 0.022044
ENSG00000108179 BRCA Amp 4.108827 0.200413 0.781616 0.138889
ENSG00000108179 STAD Amp 1.709658 0.162085 0.574129 0.185941
ENSG00000108179 UCEC Amp 4.906684 0.181033 0.759542 0.244898
ENSG00000108179 UCEC Del 0.814433 0.049211 0.514274 0.092764