Ensembl ID ENSG00000108107 Gene ID 6158 Accession 10330
Gene Symbol RPL28 Alias L28;eL28 Full Name ribosomal protein L28
Position 19 : 55385932 - 55403250 Length 17319 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L28E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]

ENSG00000108107 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000108107 RPL28 1.11 3.33e-31 KIRC
ENSG00000108107 RPL28 0.62 1.31e-13 BRCA
ENSG00000108107 RPL28 0.85 2.51e-14 PRAD
ENSG00000108107 RPL28 1.05 3.58e-14 KIRP
ENSG00000108107 RPL28 1.04 8.35e-11 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000108107 RPL28 tumor 31506518
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000108107 RPL28 MESO 0.047 high
ENSG00000108107 RPL28 SARC 0.002 high
ENSG00000108107 RPL28 CHOL 0.025 high
ENSG00000108107 RPL28 PAAD 0.012 low
ENSG00000108107 RPL28 UCEC 0.024 low
ENSG00000108107 RPL28 LUSC 0.013 low
ENSG00000108107 RPL28 HNSC 0.031 high
ENSG00000108107 RPL28 KIRP 0.0037 high
ENSG00000108107 RPL28 KICH 0.0068 high
ENSG00000108107 RPL28 LUAD 0.0083 high
ENSG00000108107 RPL28 PCPG 0.012 high
ENSG00000108107 RPL28 BRCA 0.0058 low
ENSG00000108107 RPL28 COAD 0.01 high
ENSG00000108107 RPL28 ESCA 0.049 high
ENSG00000108107 RPL28 OV 0.05 low
ENSG00000108107 RPL28 BLCA 0.006 low
ENSG00000108107 RPL28 LAML 0.005 high
ENSG00000108107 RPL28 SKCM 0.021 high
ENSG00000108107 RPL28 LIHC 0.03 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000108107 RPL28 LUSC Del 2.379900 0.087520 0.368192 0.253493
ENSG00000108107 RPL28 LUAD Del 0.810475 0.052874 0.319954 0.333333
ENSG00000108107 RPL28 LGG Del 27.642805 0.186773 0.662324 0.539961
ENSG00000108107 RPL28 CESC Amp 1.021671 0.141191 0.583350 0.322034
ENSG00000108107 RPL28 SARC Del 3.557193 0.190412 0.445193 0.342412
ENSG00000108107 RPL28 GBM Del 9.217979 0.120649 0.527272 0.150780
ENSG00000108107 RPL28 TGCT Del 1.074585 0.064959 0.339375 0.380000
ENSG00000108107 RPL28 DLBC Amp 1.472895 0.262236 0.709977 0.187500
ENSG00000108107 RPL28 BLCA Amp 1.813735 0.203762 0.493480 0.392157
ENSG00000108107 RPL28 BRCA Amp 2.092970 0.171683 0.533725 0.252778
ENSG00000108107 RPL28 STAD Amp 1.006044 0.141055 0.514581 0.244898
ENSG00000108107 RPL28 UCEC Del 0.790905 0.049011 0.474780 0.105751
ENSG00000108107 RPL28 OV Del 8.268099 0.282910 0.572728 0.454231