Ensembl ID ENSG00000107959 Gene ID 10531 Accession 17663
Gene Symbol PITRM1 Alias MP1;PreP;SCAR30 Full Name pitrilysin metallopeptidase 1
Position 10 : 3137728 - 3172841 Length 35114 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease. [provided by RefSeq, Dec 2016]

ENSG00000107959 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000107959 PITRM1 breast cancer 10096547
ENSG00000107959 PITRM1 tumour 10362099
ENSG00000107959 PITRM1 tumor 11522625
ENSG00000107959 PITRM1 lung cancer 12470903
ENSG00000107959 PITRM1 cancer 15386409
ENSG00000107959 PITRM1 tumor 15507526
ENSG00000107959 PITRM1 tumour 15671071
ENSG00000107959 PITRM1 breast cancer 15707890
ENSG00000107959 PITRM1 tumor 15967107
ENSG00000107959 PITRM1 tumor 16466631
ENSG00000107959 PITRM1 tumors 16536875
ENSG00000107959 PITRM1 tumor 17344429
ENSG00000107959 PITRM1 prostate cancer 17616675
ENSG00000107959 PITRM1 prostate cancer 19930650
ENSG00000107959 PITRM1 ovarian cancer 20570895
ENSG00000107959 PITRM1 cancer 20973496
ENSG00000107959 PITRM1 breast cancer 21670150
ENSG00000107959 PITRM1 tumors 21835828
ENSG00000107959 PITRM1 HNSCC 21945070
ENSG00000107959 PITRM1 tumor 22086466
ENSG00000107959 PITRM1 tumors 22143885
ENSG00000107959 PITRM1 cancers 22573325
ENSG00000107959 PITRM1 breast cancer 22776333
ENSG00000107959 PITRM1 breast cancer 23063352
ENSG00000107959 PITRM1 breast cancer 23341997
ENSG00000107959 PITRM1 GBM 23791361
ENSG00000107959 PITRM1 tumors 24212716
ENSG00000107959 PITRM1 tumors 2446567
ENSG00000107959 PITRM1 tumor 24469254
ENSG00000107959 PITRM1 prostate cancer 24805876
ENSG00000107959 PITRM1 prostate cancer 24841562
ENSG00000107959 PITRM1 cancer 25287047
ENSG00000107959 PITRM1 tumours 25874673
ENSG00000107959 PITRM1 cervical cancer 26006035
ENSG00000107959 PITRM1 cancer 26331251
ENSG00000107959 PITRM1 cancer 26392299
ENSG00000107959 PITRM1 cancer 26805885
ENSG00000107959 PITRM1 uterine cervical cancer 2752496
ENSG00000107959 PITRM1 lung cancer 28187172
ENSG00000107959 PITRM1 cancer 28274844
ENSG00000107959 PITRM1 oral cancer 28276309
ENSG00000107959 PITRM1 lung cancer 28606806
ENSG00000107959 PITRM1 cancer 28704971
ENSG00000107959 PITRM1 tumor 28802697
ENSG00000107959 PITRM1 cancer 28830458
ENSG00000107959 PITRM1 breast cancers 29516929
ENSG00000107959 PITRM1 endometrial cancer 29523216
ENSG00000107959 PITRM1 tumor 29789901
ENSG00000107959 PITRM1 tumor 31455317
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000107959 PITRM1 MESO 0.019 low
ENSG00000107959 PITRM1 CHOL 0.019 low
ENSG00000107959 PITRM1 PAAD 0.0083 low
ENSG00000107959 PITRM1 THCA 0.0066 high
ENSG00000107959 PITRM1 ACC 0.0016 high
ENSG00000107959 PITRM1 LUSC 0.043 high
ENSG00000107959 PITRM1 READ 0.0032 high
ENSG00000107959 PITRM1 KICH 0.0022 high
ENSG00000107959 PITRM1 PCPG 0.022 low
ENSG00000107959 PITRM1 BRCA 0.00099 high
ENSG00000107959 PITRM1 UCS 0.0035 high
ENSG00000107959 PITRM1 KIRC 0.00051 high
ENSG00000107959 PITRM1 BLCA 0.041 high
ENSG00000107959 PITRM1 LAML 0.0014 high
ENSG00000107959 PITRM1 GBM 0.0057 low
ENSG00000107959 PITRM1 SKCM 7e-04 high
ENSG00000107959 PITRM1 CESC 0.0045 high
ENSG00000107959 PITRM1 LIHC 0.00019 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000107959 PITRM1 LUSC Del 1.817019 0.081037 0.370020 0.437126
ENSG00000107959 PITRM1 LUAD Del 1.981291 0.067141 0.321886 0.244186
ENSG00000107959 PITRM1 LGG Amp 3.176886 0.078513 0.726202 0.134503
ENSG00000107959 PITRM1 SARC Del 0.670814 0.119218 0.559756 0.470817
ENSG00000107959 PITRM1 BLCA Amp 4.640558 0.281154 0.607193 0.419118
ENSG00000107959 PITRM1 BRCA Amp 1.731208 0.165569 0.606167 0.270370
ENSG00000107959 PITRM1 MESO Del 1.834150 0.170486 0.516703 0.333333
ENSG00000107959 PITRM1 OV Amp 2.151915 0.378922 0.737858 0.443869