Ensembl ID
ENSG00000107929
Gene ID
23185
Accession
28987
Gene Symbol
LARP4B
Alias
LARP5;KIAA0217
Full Name
La ribonucleoprotein 4B
Position
10 : 806933 - 931821
Length
124889 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
This gene encodes a member of an evolutionarily conserved protein family implicated in RNA metabolism and translation. Members of this family are characterized by the presence of an La motif, which is often located adjacent to one or more RNA recognition motifs (RRM). Together, the two motifs constitute the functional region of the protein and enable its interaction with the RNA substrate. This protein family is divided into five sub-families: the genuine La proteins and four La-related protein (LARP) sub-families. The protein encoded by this gene belongs to LARP sub-family 4. It is a cytoplasmic protein that may play a stimulatory role in translation. [provided by RefSeq, Oct 2012]
ENSG00000107929 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000107929
LARP4B
0.54
5.14e-29
BRCA
ENSG00000107929
LARP4B
0.66
1.66e-21
UCEC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000107929
LARP4B
acute myeloid leukemia (AML)
25534202
ENSG00000107929
LARP4B
Tumor
26933087
ENSG00000107929
LARP4B
cancers
28649990
ENSG00000107929
LARP4B
prostate cancer
31173237
ENSG00000107929
LARP4B
Liver Cancer
31772683
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000107929
LARP4B
MESO
0.0022
low
show
ENSG00000107929
LARP4B
SARC
0.026
high
show
ENSG00000107929
LARP4B
STAD
0.0076
low
show
ENSG00000107929
LARP4B
CHOL
0.025
low
show
ENSG00000107929
LARP4B
PAAD
0.023
low
show
ENSG00000107929
LARP4B
THCA
0.0098
high
show
ENSG00000107929
LARP4B
ACC
0.00039
high
show
ENSG00000107929
LARP4B
HNSC
0.003
low
show
ENSG00000107929
LARP4B
KIRP
0.017
low
show
ENSG00000107929
LARP4B
KICH
0.034
low
show
ENSG00000107929
LARP4B
LUAD
0.042
low
show
ENSG00000107929
LARP4B
PCPG
0.0012
low
show
ENSG00000107929
LARP4B
THYM
0.023
low
show
ENSG00000107929
LARP4B
BRCA
0.008
high
show
ENSG00000107929
LARP4B
OV
0.037
low
show
ENSG00000107929
LARP4B
PRAD
0.033
low
show
ENSG00000107929
LARP4B
GBM
0.0054
low
show
ENSG00000107929
LARP4B
SKCM
0.049
low
show
ENSG00000107929
LARP4B
LIHC
0.00022
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000107929
LARP4B
LUSC
Del
6.373817
0.124688
0.388358
0.453094
ENSG00000107929
LARP4B
LUAD
Del
4.087207
0.085815
0.332057
0.253876
ENSG00000107929
LARP4B
LGG
Amp
4.107918
0.089359
0.739392
0.132554
ENSG00000107929
LARP4B
COAD
Del
0.701296
0.042250
0.344460
0.177384
ENSG00000107929
LARP4B
SARC
Del
14.980104
0.356811
0.643816
0.498054
ENSG00000107929
LARP4B
GBM
Del
2.058091
0.067924
0.691974
0.818024
ENSG00000107929
LARP4B
PAAD
Del
0.715301
0.045895
0.364824
0.222826
ENSG00000107929
LARP4B
ESCA
Del
1.325901
0.114737
0.422065
0.293478
ENSG00000107929
LARP4B
SKCM
Del
4.229825
0.113870
0.547065
0.542234
ENSG00000107929
LARP4B
HNSC
Del
1.301998
0.061599
0.378471
0.325670
ENSG00000107929
LARP4B
TGCT
Del
1.256544
0.070733
0.369877
0.560000
ENSG00000107929
LARP4B
BLCA
Amp
3.319017
0.248168
0.572228
0.401961
ENSG00000107929
LARP4B
BRCA
Amp
2.042632
0.170805
0.611245
0.269444
ENSG00000107929
LARP4B
STAD
Del
0.672119
0.059902
0.398741
0.174603
ENSG00000107929
LARP4B
MESO
Del
1.775449
0.167997
0.526301
0.321839
ENSG00000107929
LARP4B
OV
Amp
3.618652
0.418948
0.771938
0.435233
ENSG00000107929
LARP4B
OV
Del
1.094604
0.183994
0.583417
0.207254
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