Ensembl ID ENSG00000107614 Gene ID 1787 Accession 2977
Gene Symbol TRDMT1 Alias DMNT2;DNMT2;PUMET;RNMT1;MHSAIIP Full Name tRNA aspartic acid methyltransferase 1
Position 10 : 17137336 - 17201851 Length 64516 bases Strand Minus strand
Status Confidence Main interacting RNAstRNARBP type Non-canonical_RBPs
Summary This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. [provided by RefSeq, Jun 2010]

ENSG00000107614 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000107614 TRDMT1 -0.5 4.36e-11 BRCA
ENSG00000107614 TRDMT1 -1.5 1.95e-21 KICH
ENSG00000107614 TRDMT1 -0.7 9.54e-12 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000107614 TRDMT1 stomach cancers 11146446
ENSG00000107614 TRDMT1 cancers 15721400
ENSG00000107614 TRDMT1 lung cancer 17533396
ENSG00000107614 TRDMT1 tumor 19680556
ENSG00000107614 TRDMT1 cancer 19808971
ENSG00000107614 TRDMT1 cancer 22942708
ENSG00000107614 TRDMT1 breast cancer 23079992
ENSG00000107614 TRDMT1 cancer 24079712
ENSG00000107614 TRDMT1 tumor 24648923
ENSG00000107614 TRDMT1 cancer 25747896
ENSG00000107614 TRDMT1 colorectal cancer 25948668
ENSG00000107614 TRDMT1 cancer 27232191
ENSG00000107614 TRDMT1 tumor 28843151
ENSG00000107614 TRDMT1 cancer 29125541
ENSG00000107614 TRDMT1 Wilms’ tumor 29900123
ENSG00000107614 TRDMT1 tumor 30588513
ENSG00000107614 TRDMT1 tumor 31394707
ENSG00000107614 TRDMT1 prostate cancer 31864524
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000107614 TRDMT1 MESO 0.008 high
ENSG00000107614 TRDMT1 SARC 2e-04 high
ENSG00000107614 TRDMT1 ACC 0.0055 high
ENSG00000107614 TRDMT1 KICH 0.0011 high
ENSG00000107614 TRDMT1 LUAD 0.00053 low
ENSG00000107614 TRDMT1 PCPG 0.011 high
ENSG00000107614 TRDMT1 THYM 0.00019 low
ENSG00000107614 TRDMT1 COAD 0.00036 low
ENSG00000107614 TRDMT1 UCS 0.049 low
ENSG00000107614 TRDMT1 DLBC 0.033 low
ENSG00000107614 TRDMT1 KIRC 0.00053 low
ENSG00000107614 TRDMT1 PRAD 0.012 high
ENSG00000107614 TRDMT1 BLCA 0.031 high
ENSG00000107614 TRDMT1 GBM 0.003 low
ENSG00000107614 TRDMT1 CESC 0.018 high
ENSG00000107614 TRDMT1 LIHC 0.00025 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency