Ensembl ID ENSG00000107105 Gene ID 1993 Accession 3313
Gene Symbol ELAVL2 Alias HUB;HELN1;HEL-N1 Full Name ELAV like RNA binding protein 2
Position 9 : 23690104 - 23826337 Length 136234 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary In humans, the ELAV like RNA binding protein gene family has four members (ELAVL1-4). ELAVL RNA binding proteins recognize AU-rich elements in the 3' UTRs of gene transcripts and thereby regulate gene expression post-transcriptionally. The protein encoded by this gene binds to several 3' UTRs, including its own and also that of FOS, ID, and POU5F1. This gene encodes ELAVL2 and, like ELAVL3 and ELAVL4, is expressed specifically in neurons and primarily localizes to the cytoplasm. This protein also forms a cytosolic complex with the normally nuclear-localized ELAVL1 protein. Alternative splicing of this gene results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Jul 2020]

ENSG00000107105 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000107105 ELAVL2 2.21 1.02e-11 HNSC
ENSG00000107105 ELAVL2 2.61 1.72e-50 BRCA
ENSG00000107105 ELAVL2 5.64 1.39e-53 KICH
ENSG00000107105 ELAVL2 2.95 6.77e-15 LUSC
ENSG00000107105 ELAVL2 2.24 4.34e-21 PRAD
ENSG00000107105 ELAVL2 2.46 1.31e-11 LIHC
ENSG00000107105 ELAVL2 3.44 1.87e-24 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000107105 ELAVL2 tumor 23029397
ENSG00000107105 ELAVL2 lung cancer 24379827
ENSG00000107105 ELAVL2 cancer 24458129
ENSG00000107105 ELAVL2 cancers 25239644
ENSG00000107105 ELAVL2 tumor 26914213
ENSG00000107105 ELAVL2 tumors 28035070
ENSG00000107105 ELAVL2 cancer 29029427
ENSG00000107105 ELAVL2 liver cancer 29250165
ENSG00000107105 ELAVL2 cancer 29991691
ENSG00000107105 ELAVL2 cervical cancer 30696738
ENSG00000107105 ELAVL2 esophageal tumors 31285951
ENSG00000107105 ELAVL2 Cancer 31453359
ENSG00000107105 ELAVL2 cancer 31695102
ENSG00000107105 ELAVL2 GBM 31719831
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000107105 ELAVL2 SARC 0.014 high
ENSG00000107105 ELAVL2 STAD 0.0085 high
ENSG00000107105 ELAVL2 UVM 0.024 high
ENSG00000107105 ELAVL2 PAAD 0.00078 low
ENSG00000107105 ELAVL2 THCA 0.043 low
ENSG00000107105 ELAVL2 ACC 0.00026 low
ENSG00000107105 ELAVL2 HNSC 0.01 high
ENSG00000107105 ELAVL2 READ 0.039 high
ENSG00000107105 ELAVL2 KIRP 0.034 high
ENSG00000107105 ELAVL2 LUAD 0.029 high
ENSG00000107105 ELAVL2 PCPG 0.047 high
ENSG00000107105 ELAVL2 THYM 0.0033 low
ENSG00000107105 ELAVL2 UCS 0.038 low
ENSG00000107105 ELAVL2 ESCA 0.0092 high
ENSG00000107105 ELAVL2 TGCT 0.016 low
ENSG00000107105 ELAVL2 CESC 0.005 low
ENSG00000107105 ELAVL2 LIHC 0.041 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000107105 ELAVL2 LUSC Del 64.195544 0.402374 0.513198 0.724551
ENSG00000107105 ELAVL2 LUAD Del 27.681503 0.212124 0.423579 0.546512
ENSG00000107105 ELAVL2 LGG Del 38.208156 0.225394 0.621717 0.309942
ENSG00000107105 ELAVL2 KIRP Del 2.745432 0.046238 0.641633 0.131944
ENSG00000107105 ELAVL2 ACC Del 1.217985 0.120294 0.655467 0.277778
ENSG00000107105 ELAVL2 SARC Del 4.958263 0.216109 0.599778 0.400778
ENSG00000107105 ELAVL2 GBM Del 219.161830 0.786751 0.851146 0.625650
ENSG00000107105 ELAVL2 PAAD Del 17.717640 0.235947 0.454613 0.527174
ENSG00000107105 ELAVL2 ESCA Del 13.270376 0.329502 0.508542 0.625000
ENSG00000107105 ELAVL2 SKCM Del 24.834741 0.273170 0.615811 0.700272
ENSG00000107105 ELAVL2 HNSC Del 16.267225 0.153687 0.492665 0.440613
ENSG00000107105 ELAVL2 LIHC Del 4.058406 0.111191 0.536115 0.348649
ENSG00000107105 ELAVL2 BLCA Del 38.317142 0.359822 0.603260 0.487745
ENSG00000107105 ELAVL2 BRCA Del 4.150763 0.088116 0.457544 0.316667
ENSG00000107105 ELAVL2 STAD Del 13.096917 0.165221 0.468253 0.405896
ENSG00000107105 ELAVL2 MESO Del 24.739756 0.690656 0.837030 0.482759
ENSG00000107105 ELAVL2 OV Del 1.014300 0.182125 0.617321 0.443869