Ensembl ID ENSG00000106588 Gene ID 5683 Accession 9531
Gene Symbol PSMA2 Alias MU;HC3;PSC2;PMSA2 Full Name proteasome 20S subunit alpha 2
Position 7 : 42916861 - 42932185 Length 15325 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq, Jul 2008]

ENSG00000106588 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000106588 0.47 5.29e-17 BRCA
ENSG00000106588 0.65 1.20e-12 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000106588 cancer 12958220
ENSG00000106588 ovarian cancer 14960231
ENSG00000106588 tumors 22685613
ENSG00000106588 tumors 22937035
ENSG00000106588 cancer 27966459
ENSG00000106588 AML 29781401
ENSG00000106588 tumor 31150679
ENSG00000106588 tumours 31619667
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000106588 CHOL 0.045 low
ENSG00000106588 UCEC 0.016 high
ENSG00000106588 ACC 0.00035 high
ENSG00000106588 LUSC 0.028 low
ENSG00000106588 KICH 0.0044 high
ENSG00000106588 LUAD 0.00065 high
ENSG00000106588 BRCA 0.016 high
ENSG00000106588 ESCA 0.00035 high
ENSG00000106588 KIRC 8e-04 high
ENSG00000106588 BLCA 0.0083 low
ENSG00000106588 GBM 0.039 high
ENSG00000106588 SKCM 0.00031 low
ENSG00000106588 CESC 0.014 low
ENSG00000106588 LIHC 0.00017 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency