Ensembl ID ENSG00000106263 Gene ID 8662 Accession 3280
Gene Symbol EIF3B Alias PRT1;EIF3S9;EIF3-ETA;EIF3-P110;EIF3-P116 Full Name eukaryotic translation initiation factor 3 subunit B
Position 7 : 2354086 - 2380745 Length 26660 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Enables RNA binding activity. Contributes to translation initiation factor activity. Involved in several processes, including IRES-dependent viral translational initiation; translational initiation; and viral translational termination-reinitiation. Located in extracellular exosome. Part of eukaryotic translation initiation factor 3 complex. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000106263 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000106263 EIF3B 0.63 8.43e-34 KIRC
ENSG00000106263 EIF3B 0.43 1.54e-14 BRCA
ENSG00000106263 EIF3B 1.13 6.82e-39 COAD
ENSG00000106263 EIF3B 0.62 3.91e-14 KICH
ENSG00000106263 EIF3B 1.24 4.64e-13 READ
ENSG00000106263 EIF3B 1.18 9.61e-53 LUSC
ENSG00000106263 EIF3B 0.67 4.94e-22 PRAD
ENSG00000106263 EIF3B 0.66 1.97e-14 KIRP
ENSG00000106263 EIF3B 0.94 2.77e-30 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000106263 EIF3B cancer 11169732
ENSG00000106263 EIF3B colon cancer 22734884
ENSG00000106263 EIF3B tumor 23575475
ENSG00000106263 EIF3B GBM 24481065
ENSG00000106263 EIF3B tumors 27270324
ENSG00000106263 EIF3B cancers 28083147
ENSG00000106263 EIF3B tumour 28360085
ENSG00000106263 EIF3B tumor 28928896
ENSG00000106263 EIF3B non-small cell lung cancer 30198870
ENSG00000106263 EIF3B cancer 30416377
ENSG00000106263 EIF3B ovarian cancer 30551537
ENSG00000106263 EIF3B tumor 31171919
ENSG00000106263 EIF3B cervical cancer 31322539
ENSG00000106263 EIF3B gastric cancer 31423012
ENSG00000106263 EIF3B tumor 31481019
ENSG00000106263 EIF3B cancer 31686906
ENSG00000106263 EIF3B prostate cancers 31778600
ENSG00000106263 EIF3B endometrial cancer 31934209
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000106263 EIF3B MESO 0.0099 high
ENSG00000106263 EIF3B SARC 0.0043 high
ENSG00000106263 EIF3B CHOL 0.013 low
ENSG00000106263 EIF3B UVM 0.0036 high
ENSG00000106263 EIF3B UCEC 0.014 low
ENSG00000106263 EIF3B LGG 0.011 high
ENSG00000106263 EIF3B LUSC 0.019 low
ENSG00000106263 EIF3B HNSC 0.00022 high
ENSG00000106263 EIF3B READ 0.033 low
ENSG00000106263 EIF3B KIRP 0.0053 high
ENSG00000106263 EIF3B KICH 0.0012 high
ENSG00000106263 EIF3B LUAD 0.00084 high
ENSG00000106263 EIF3B BRCA 0.0023 high
ENSG00000106263 EIF3B COAD 0.019 high
ENSG00000106263 EIF3B UCS 0.025 high
ENSG00000106263 EIF3B OV 0.032 high
ENSG00000106263 EIF3B DLBC 0.0036 low
ENSG00000106263 EIF3B KIRC 0.00048 high
ENSG00000106263 EIF3B BLCA 0.0072 high
ENSG00000106263 EIF3B GBM 0.0099 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000106263 EIF3B SKCM Amp 3.035971 0.190667 0.718609 0.553134
ENSG00000106263 EIF3B HNSC Amp 1.173903 0.128434 0.521152 0.400383
ENSG00000106263 EIF3B TGCT Amp 1.308797 0.145181 0.549792 0.820000
ENSG00000106263 EIF3B BRCA Del 0.658225 0.062854 0.414636 0.127778
ENSG00000106263 EIF3B UCEC Del 3.189874 0.074319 0.499400 0.131725
ENSG00000106263 EIF3B OV Del 23.686990 0.408004 0.622652 0.426598