Ensembl ID
ENSG00000106246
Gene ID
26024
Accession
22198
Gene Symbol
PTCD1
Alias
NA
Full Name
pentatricopeptide repeat domain 1
Position
7 : 99416739 - 99466163
Length
49425 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs tRNA RBP type
Canonical_RBPs
Summary
This gene encodes a mitochondrial protein that binds leucine tRNAs and other mitochondrial RNAs and plays a role in the regulation of translation. Increased expression of this gene results in decreased mitochondrial leucine tRNA levels. Naturally occurring read-through transcription exists between upstream ATP5J2 (ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2) and this gene. [provided by RefSeq, Aug 2015]
ENSG00000106246 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000106246
PTCD1
0.54
3.15e-21
BRCA
ENSG00000106246
PTCD1
0.76
4.47e-13
COAD
ENSG00000106246
PTCD1
1.01
5.50e-28
LUSC
ENSG00000106246
PTCD1
0.79
4.33e-16
KIRP
ENSG00000106246
PTCD1
0.79
3.13e-16
LIHC
ENSG00000106246
PTCD1
0.80
5.39e-11
STAD
ENSG00000106246
PTCD1
0.71
3.53e-12
UCEC
ENSG00000106246
PTCD1
0.65
3.57e-15
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000106246
PTCD1
PAAD
0.0084
low
show
ENSG00000106246
PTCD1
UCEC
0.038
high
show
ENSG00000106246
PTCD1
LGG
0.00093
high
show
ENSG00000106246
PTCD1
LUSC
0.0054
low
show
ENSG00000106246
PTCD1
HNSC
0.018
low
show
ENSG00000106246
PTCD1
KIRP
0.00049
low
show
ENSG00000106246
PTCD1
KICH
0.021
high
show
ENSG00000106246
PTCD1
PCPG
0.00025
low
show
ENSG00000106246
PTCD1
THYM
0.017
high
show
ENSG00000106246
PTCD1
BRCA
0.0017
low
show
ENSG00000106246
PTCD1
COAD
0.027
low
show
ENSG00000106246
PTCD1
ESCA
0.039
high
show
ENSG00000106246
PTCD1
OV
0.037
high
show
ENSG00000106246
PTCD1
BLCA
0.00044
low
show
ENSG00000106246
PTCD1
LAML
0.02
low
show
ENSG00000106246
PTCD1
GBM
0.029
high
show
ENSG00000106246
PTCD1
SKCM
0.00053
high
show
ENSG00000106246
PTCD1
CESC
0.042
low
show
ENSG00000106246
PTCD1
LIHC
0.00024
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000106246
PTCD1
LUSC
Amp
2.071340
0.237474
0.554683
0.508982
ENSG00000106246
PTCD1
LUAD
Amp
0.655235
0.115474
0.456181
0.430233
ENSG00000106246
PTCD1
LGG
Amp
1.724128
0.058951
0.661646
0.319688
ENSG00000106246
PTCD1
PAAD
Amp
2.779784
0.148340
0.496644
0.304348
ENSG00000106246
PTCD1
ESCA
Amp
8.719068
0.620860
0.804679
0.570652
ENSG00000106246
PTCD1
HNSC
Amp
7.792569
0.246802
0.608326
0.329502
ENSG00000106246
PTCD1
STAD
Amp
12.524325
0.367521
0.663383
0.453515
ENSG00000106246
PTCD1
PRAD
Amp
1.117396
0.051992
0.514307
0.205285
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.