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| Ensembl ID | ENSG00000106211 | Gene ID | 3315 | Accession | 5246 |
| Gene Symbol | HSPB1 | Alias | CMT2F;HMN2B;HSP27;HSP28;Hsp25;SRP27;HS.76067;HEL-S-102 | Full Name | heat shock protein family B (small) member 1 |
| Position | 7 : 76302673 - 76304295 | Length | 1623 bases | Strand | Plus strand |
| Status | Confidence | Main interacting RNAs | N.A. | RBP type | Non-canonical_RBPs |
| Summary | This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017] | ||||
ENSG00000106211 Expression In 33 Tumors
| Ensembl ID | Gene symbol | Log2 Foldchange | Pvaue | Cancer |
|---|---|---|---|---|
| ENSG00000106211 | 0.82 | 7.63e-12 | KIRC | |
| ENSG00000106211 | 1.52 | 3.10e-34 | BRCA | |
| ENSG00000106211 | 1.33 | 2.77e-15 | KICH | |
| ENSG00000106211 | 2.04 | 4.38e-43 | LUSC | |
| ENSG00000106211 | 1.53 | 2.41e-21 | KIRP | |
| ENSG00000106211 | 1.64 | 1.02e-25 | LIHC |
| Ensembl ID | Gene symbol | Cancer types | Pubmed ID |
|---|---|---|---|
| ENSG00000106211 | ovarian cancer | 10226541 | |
| ENSG00000106211 | tumour | 10356405 | |
| ENSG00000106211 | tumors | 10861421 | |
| ENSG00000106211 | tumours | 11078920 | |
| ENSG00000106211 | tumor | 11429196 | |
| ENSG00000106211 | tumors | 11849747 | |
| ENSG00000106211 | tumor | 1313743 | |
| ENSG00000106211 | lung cancer | 14688473 | |
| ENSG00000106211 | tumors | 15351573 | |
| ENSG00000106211 | breast cancer | 15833836 | |
| ENSG00000106211 | tumor | 16648970 | |
| ENSG00000106211 | tumor | 16696328 | |
| ENSG00000106211 | tumour | 16720063 | |
| ENSG00000106211 | AML | 17693191 | |
| ENSG00000106211 | tumors | 17883861 | |
| ENSG00000106211 | tumor | 19189670 | |
| ENSG00000106211 | gastric cancer | 19203381 | |
| ENSG00000106211 | cancer | 19367286 | |
| ENSG00000106211 | trophoblastic tumor | 19575256 | |
| ENSG00000106211 | tumors | 19643972 | |
| ENSG00000106211 | prostate cancer | 19707199 | |
| ENSG00000106211 | cancer | 20145720 | |
| ENSG00000106211 | lung cancer | 20231684 | |
| ENSG00000106211 | tumour | 20702176 | |
| ENSG00000106211 | cancer | 21113302 | |
| ENSG00000106211 | tumour | 21114636 | |
| ENSG00000106211 | cancers | 21225769 | |
| ENSG00000106211 | cancer | 21225770 | |
| ENSG00000106211 | cancer | 21423207 | |
| ENSG00000106211 | GBM | 21470419 | |
| ENSG00000106211 | pancreatic cancer | 21833720 | |
| ENSG00000106211 | non-small-cell lung cancer | 21937138 | |
| ENSG00000106211 | tumour | 21961414 | |
| ENSG00000106211 | colorectal cancer | 21989268 | |
| ENSG00000106211 | tumors | 22083493 | |
| ENSG00000106211 | tumor | 22350794 | |
| ENSG00000106211 | breast cancer | 22384035 | |
| ENSG00000106211 | tumors | 22452810 | |
| ENSG00000106211 | lung cancer | 22500095 | |
| ENSG00000106211 | colorectal cancer | 22515340 | |
| ENSG00000106211 | tumor | 22539317 | |
| ENSG00000106211 | non-small cell lung cancer | 22608953 | |
| ENSG00000106211 | tumour | 22627320 | |
| ENSG00000106211 | cancer | 22683760 | |
| ENSG00000106211 | colorectal cancer | 22799385 | |
| ENSG00000106211 | cancer | 22804237 | |
| ENSG00000106211 | cancer | 22804238 | |
| ENSG00000106211 | gastric cancer | 22860099 | |
| ENSG00000106211 | breast cancer | 22907762 | |
| ENSG00000106211 | cancer | 22984562 | |
| ENSG00000106211 | cancer | 22989709 | |
| ENSG00000106211 | prostate cancer | 23165430 | |
| ENSG00000106211 | cancer | 23227181 | |
| ENSG00000106211 | nerve sheath tumours | 23348018 | |
| ENSG00000106211 | non-small cell lung cancer | 23374503 | |
| ENSG00000106211 | oral cancer | 23453029 | |
| ENSG00000106211 | prostate cancer | 23492367 | |
| ENSG00000106211 | cancer | 23530261 | |
| ENSG00000106211 | tumor | 24078811 | |
| ENSG00000106211 | tumour | 24143227 | |
| ENSG00000106211 | pancreatic cancer | 24175808 | |
| ENSG00000106211 | cancer | 24213112 | |
| ENSG00000106211 | tumor | 24222130 | |
| ENSG00000106211 | cancer | 24278676 | |
| ENSG00000106211 | breast cancer | 24307543 | |
| ENSG00000106211 | Tumor | 24465581 | |
| ENSG00000106211 | Cancers | 24514166 | |
| ENSG00000106211 | tumour | 24569473 | |
| ENSG00000106211 | tumor | 24812703 | |
| ENSG00000106211 | GBM | 24838487 | |
| ENSG00000106211 | gastric cancer | 24903273 | |
| ENSG00000106211 | prostate cancer | 24982356 | |
| ENSG00000106211 | cancer | 25126737 | |
| ENSG00000106211 | prostate cancer | 25193387 | |
| ENSG00000106211 | cancer | 25392686 | |
| ENSG00000106211 | breast cancer | 25454514 | |
| ENSG00000106211 | breast cancer | 25519015 | |
| ENSG00000106211 | breast cancer | 25541910 | |
| ENSG00000106211 | cancer | 25728673 | |
| ENSG00000106211 | Lung Cancer | 25811031 | |
| ENSG00000106211 | tumours | 25980435 | |
| ENSG00000106211 | tumor | 26108672 | |
| ENSG00000106211 | tumor | 26158290 | |
| ENSG00000106211 | tumor | 26305875 | |
| ENSG00000106211 | prostate cancer | 26434601 | |
| ENSG00000106211 | cancer | 26675522 | |
| ENSG00000106211 | cancer | 26744531 | |
| ENSG00000106211 | Pancreatic Cancer | 26805817 | |
| ENSG00000106211 | Breast Cancer | 26847234 | |
| ENSG00000106211 | lung cancer | 26874728 | |
| ENSG00000106211 | tumor | 27351523 | |
| ENSG00000106211 | Ovarian Cancer | 27354589 | |
| ENSG00000106211 | cancer | 27449291 | |
| ENSG00000106211 | cancer | 27555231 | |
| ENSG00000106211 | cancer | 27626679 | |
| ENSG00000106211 | prostate cancer | 27708246 | |
| ENSG00000106211 | cervical cancer | 27860262 | |
| ENSG00000106211 | cervical cancer | 28337643 | |
| ENSG00000106211 | tumors | 28468249 | |
| ENSG00000106211 | tumor | 28608263 | |
| ENSG00000106211 | cancer | 28754978 | |
| ENSG00000106211 | ovarian cancer | 28857608 | |
| ENSG00000106211 | colorectal cancer | 28903393 | |
| ENSG00000106211 | tumors | 28918740 | |
| ENSG00000106211 | non-small cell lung cancer | 29017331 | |
| ENSG00000106211 | cancer | 29285257 | |
| ENSG00000106211 | tumor | 29332450 | |
| ENSG00000106211 | tumor | 29502008 | |
| ENSG00000106211 | cancer | 29650953 | |
| ENSG00000106211 | cancers | 29753870 | |
| ENSG00000106211 | tumours | 29954368 | |
| ENSG00000106211 | tumor | 29966326 | |
| ENSG00000106211 | thyroid cancer | 29997231 | |
| ENSG00000106211 | HNSCC | 30157864 | |
| ENSG00000106211 | tumor | 30344796 | |
| ENSG00000106211 | metastatic tumor | 30396985 | |
| ENSG00000106211 | cervical cancer | 30696738 | |
| ENSG00000106211 | lung cancer | 31015126 | |
| ENSG00000106211 | lung cancer | 31015163 | |
| ENSG00000106211 | Cancer | 31139280 | |
| ENSG00000106211 | tumor | 31364192 | |
| ENSG00000106211 | prostate cancer | 31428571 | |
| ENSG00000106211 | cancers | 31533245 | |
| ENSG00000106211 | cancer | 31573509 | |
| ENSG00000106211 | cancer | 31612776 | |
| ENSG00000106211 | cancer | 31749945 | |
| ENSG00000106211 | tumors | 31897148 | |
| ENSG00000106211 | breast cancer | 7579511 | |
| ENSG00000106211 | tumour | 7669571 | |
| ENSG00000106211 | tumor | 7777477 | |
| ENSG00000106211 | Cancer | 7845389 | |
| ENSG00000106211 | tumor | 8188614 | |
| ENSG00000106211 | tumors | 8852447 | |
| ENSG00000106211 | head and neck cancer | 9060543 |
| Ensembl ID | Gene symbol | Disease/phenotype | Mutation type | Mutated / Total samples | Literature |
|---|
| Ensembl ID | Gene symbol | Cancer | P-value | Which worse | show |
|---|---|---|---|---|---|
| ENSG00000106211 | MESO | 0.014 | high | ||
| ENSG00000106211 | UVM | 0.014 | low | ||
| ENSG00000106211 | PAAD | 0.0073 | high | ||
| ENSG00000106211 | UCEC | 0.0069 | low | ||
| ENSG00000106211 | ACC | 0.0012 | low | ||
| ENSG00000106211 | HNSC | 0.007 | low | ||
| ENSG00000106211 | READ | 0.00043 | high | ||
| ENSG00000106211 | KICH | 0.00082 | low | ||
| ENSG00000106211 | LUAD | 0.028 | high | ||
| ENSG00000106211 | PCPG | 0.02 | low | ||
| ENSG00000106211 | COAD | 0.0072 | high | ||
| ENSG00000106211 | KIRC | 7e-04 | high | ||
| ENSG00000106211 | LAML | 0.0036 | high | ||
| ENSG00000106211 | GBM | 0.0011 | high | ||
| ENSG00000106211 | SKCM | 3e-04 | high | ||
| ENSG00000106211 | LIHC | 0.0044 | high |
| Ensembl ID | Gene symbol | Cancer | CNV type | -log10(q-value) | G-score | average amplitude | frequency |
|---|