Ensembl ID ENSG00000105447 Gene ID 83743 Accession 21270
Gene Symbol GRWD1 Alias CDW4;GRWD;RRB1;WDR28 Full Name glutamate rich WD repeat containing 1
Position 19 : 48445841 - 48457022 Length 11182 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Non-canonical_RBPs
Summary This gene encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1 ubiquitin E3 ligase. [provided by RefSeq, Feb 2012]

ENSG00000105447 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000105447 GRWD1 0.45 6.64e-23 BRCA
ENSG00000105447 GRWD1 0.61 3.60e-16 COAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000105447 GRWD1 cancer 25990725
ENSG00000105447 GRWD1 cancer 27856536
ENSG00000105447 GRWD1 ovarian tumor 29353130
ENSG00000105447 GRWD1 cancer 29991511
ENSG00000105447 GRWD1 tumor 30498398
ENSG00000105447 GRWD1 cancer 31545368
ENSG00000105447 GRWD1 non-small cell lung cancer 31891681
ENSG00000105447 GRWD1 colorectal cancer 31903119
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000105447 GRWD1 MESO 0.0013 high
ENSG00000105447 GRWD1 SARC 0.00015 high
ENSG00000105447 GRWD1 STAD 0.042 low
ENSG00000105447 GRWD1 ACC 0.00081 high
ENSG00000105447 GRWD1 READ 0.01 low
ENSG00000105447 GRWD1 KIRP 0.00097 high
ENSG00000105447 GRWD1 LUAD 0.0054 high
ENSG00000105447 GRWD1 ESCA 0.032 low
ENSG00000105447 GRWD1 OV 0.0082 high
ENSG00000105447 GRWD1 DLBC 0.0026 low
ENSG00000105447 GRWD1 KIRC 0.02 low
ENSG00000105447 GRWD1 BLCA 0.017 high
ENSG00000105447 GRWD1 LIHC 0.00033 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000105447 GRWD1 LUSC Del 3.712193 0.101350 0.365032 0.285429
ENSG00000105447 GRWD1 LUAD Del 3.171762 0.078471 0.320792 0.374031
ENSG00000105447 GRWD1 LGG Del 15.678196 0.132957 0.664455 0.500975
ENSG00000105447 GRWD1 CESC Del 0.823547 0.069363 0.422145 0.122034
ENSG00000105447 GRWD1 UCS Del 0.913191 0.218463 0.477357 0.303571
ENSG00000105447 GRWD1 SARC Del 2.536038 0.169348 0.450811 0.326848
ENSG00000105447 GRWD1 GBM Del 11.608998 0.134909 0.526125 0.164645
ENSG00000105447 GRWD1 PAAD Del 0.901721 0.049425 0.294972 0.119565
ENSG00000105447 GRWD1 UCEC Del 1.654929 0.059857 0.483390 0.113173
ENSG00000105447 GRWD1 OV Del 14.247361 0.337697 0.581109 0.507772