Ensembl ID ENSG00000105258 Gene ID 5438 Accession 9196
Gene Symbol POLR2I Alias RPB9;hRPB14.5 Full Name RNA polymerase II subunit I
Position 19 : 36113709 - 36115213 Length 1505 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. [provided by RefSeq, Jul 2008]

ENSG00000105258 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000105258 POLR2I 0.67 2.75e-20 BRCA
ENSG00000105258 POLR2I 0.80 6.75e-17 LUSC
ENSG00000105258 POLR2I 1.20 3.02e-13 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000105258 POLR2I STAD 0.00013 high
ENSG00000105258 POLR2I UVM 0.036 high
ENSG00000105258 POLR2I PAAD 0.016 low
ENSG00000105258 POLR2I UCEC 0.0043 low
ENSG00000105258 POLR2I ACC 0.00048 high
ENSG00000105258 POLR2I LGG 0.00014 high
ENSG00000105258 POLR2I LUSC 0.00078 low
ENSG00000105258 POLR2I HNSC 0.018 high
ENSG00000105258 POLR2I READ 0.0078 high
ENSG00000105258 POLR2I KICH 0.037 high
ENSG00000105258 POLR2I PCPG 0.0046 high
ENSG00000105258 POLR2I BRCA 0.0057 low
ENSG00000105258 POLR2I OV 0.0027 low
ENSG00000105258 POLR2I KIRC 0.024 high
ENSG00000105258 POLR2I TGCT 0.0035 low
ENSG00000105258 POLR2I BLCA 0.037 low
ENSG00000105258 POLR2I SKCM 0.026 high
ENSG00000105258 POLR2I CESC 0.0099 low
ENSG00000105258 POLR2I LIHC 0.016 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000105258 POLR2I LUSC Amp 14.139539 0.463815 0.677496 0.465070
ENSG00000105258 POLR2I LUAD Amp 6.144642 0.221428 0.525981 0.267442
ENSG00000105258 POLR2I CESC Amp 2.604625 0.198688 0.720111 0.298305
ENSG00000105258 POLR2I UCS Amp 5.734308 1.149013 1.025854 0.696429
ENSG00000105258 POLR2I SARC Amp 0.941542 0.273518 0.678793 0.295720
ENSG00000105258 POLR2I PAAD Amp 1.024892 0.092490 0.436022 0.228261
ENSG00000105258 POLR2I BLCA Amp 1.415603 0.190492 0.504146 0.389706
ENSG00000105258 POLR2I UCEC Amp 3.138408 0.153475 0.736583 0.163265