Ensembl ID
ENSG00000104897
Gene ID
8175
Accession
10766
Gene Symbol
SF3A2
Alias
PRP11;SAP62;PRPF11;SF3a66
Full Name
splicing factor 3a subunit 2
Position
19 : 2236824 - 2248655
Length
11832 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs snRNA RBP type
Canonical_RBPs
Summary
This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein. [provided by RefSeq, Jul 2008]
ENSG00000104897 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000104897
SF3A2
0.96
4.70e-35
KIRC
ENSG00000104897
SF3A2
0.41
8.47e-11
BRCA
ENSG00000104897
SF3A2
0.63
6.81e-14
LUSC
ENSG00000104897
SF3A2
0.93
6.24e-18
LIHC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000104897
SF3A2
MESO
0.0035
high
show
ENSG00000104897
SF3A2
STAD
0.0038
low
show
ENSG00000104897
SF3A2
CHOL
0.024
low
show
ENSG00000104897
SF3A2
UVM
0.00015
low
show
ENSG00000104897
SF3A2
PAAD
0.0047
low
show
ENSG00000104897
SF3A2
UCEC
0.0029
low
show
ENSG00000104897
SF3A2
LUSC
0.024
low
show
ENSG00000104897
SF3A2
HNSC
0.047
low
show
ENSG00000104897
SF3A2
KIRP
0.00014
high
show
ENSG00000104897
SF3A2
LUAD
0.037
high
show
ENSG00000104897
SF3A2
THYM
0.00025
low
show
ENSG00000104897
SF3A2
BRCA
0.013
low
show
ENSG00000104897
SF3A2
COAD
0.00079
high
show
ENSG00000104897
SF3A2
KIRC
0.00035
high
show
ENSG00000104897
SF3A2
LAML
0.0028
high
show
ENSG00000104897
SF3A2
CESC
0.0033
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000104897
SF3A2
LUSC
Del
7.464338
0.132684
0.356306
0.449102
ENSG00000104897
SF3A2
LUAD
Del
3.662508
0.082458
0.351362
0.536822
ENSG00000104897
SF3A2
CESC
Del
11.780665
0.191207
0.486667
0.332203
ENSG00000104897
SF3A2
KIRP
Del
0.742956
0.027442
0.390794
0.076389
ENSG00000104897
SF3A2
READ
Del
0.637830
0.068240
0.347884
0.212121
ENSG00000104897
SF3A2
COAD
Del
1.548084
0.051612
0.393233
0.130820
ENSG00000104897
SF3A2
UCS
Del
12.450764
0.800388
0.629239
0.803571
ENSG00000104897
SF3A2
SARC
Del
2.036982
0.157974
0.429677
0.198444
ENSG00000104897
SF3A2
GBM
Amp
0.879667
0.070802
0.544702
0.414211
ENSG00000104897
SF3A2
PAAD
Del
2.088264
0.072373
0.357377
0.195652
ENSG00000104897
SF3A2
ESCA
Del
4.213760
0.182991
0.354616
0.516304
ENSG00000104897
SF3A2
SKCM
Del
0.907370
0.069915
0.335983
0.269755
ENSG00000104897
SF3A2
THCA
Del
0.928265
0.010197
0.678144
0.014028
ENSG00000104897
SF3A2
HNSC
Del
12.711505
0.135850
0.358891
0.318008
ENSG00000104897
SF3A2
LIHC
Del
5.811411
0.129625
0.466029
0.240541
ENSG00000104897
SF3A2
BLCA
Del
4.216189
0.125513
0.334365
0.350490
ENSG00000104897
SF3A2
BRCA
Del
26.723431
0.167911
0.401585
0.329630
ENSG00000104897
SF3A2
STAD
Del
3.080179
0.090835
0.362118
0.369615
ENSG00000104897
SF3A2
UCEC
Del
44.465738
0.262929
0.604793
0.272727
ENSG00000104897
SF3A2
OV
Del
132.562339
0.925956
0.654263
0.880829
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