Ensembl ID
ENSG00000104852
Gene ID
6625
Accession
11150
Gene Symbol
SNRNP70
Alias
RPU1;Snp1;U1AP;U170K;U1RNP;RNPU1Z;SNRP70;U1-70K
Full Name
small nuclear ribonucleoprotein U1 subunit 70
Position
19 : 49085419 - 49108605
Length
23187 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs snRNA RBP type
Canonical_RBPs
Summary
Enables U1 snRNA binding activity. Involved in mRNA splicing, via spliceosome and regulation of RNA splicing. Located in nucleoplasm. Part of U1 snRNP and spliceosomal complex. Implicated in disease of mental health and systemic lupus erythematosus. Biomarker of Alzheimer's disease. [provided by Alliance of Genome Resources, Apr 2022]
ENSG00000104852 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000104852
SNRNP70
0.98
4.60e-26
KIRC
ENSG00000104852
SNRNP70
0.72
4.08e-16
COAD
ENSG00000104852
SNRNP70
0.63
8.51e-13
LUSC
ENSG00000104852
SNRNP70
0.91
8.57e-21
PRAD
ENSG00000104852
SNRNP70
0.79
7.02e-22
LIHC
ENSG00000104852
SNRNP70
0.53
8.97e-11
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000104852
SNRNP70
breast cancers
21677381
ENSG00000104852
SNRNP70
tumor
26336870
ENSG00000104852
SNRNP70
gallbladder cancer
30953511
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000104852
SNRNP70
STAD
0.0035
low
show
ENSG00000104852
SNRNP70
UVM
0.0023
high
show
ENSG00000104852
SNRNP70
ACC
0.00014
high
show
ENSG00000104852
SNRNP70
HNSC
0.028
low
show
ENSG00000104852
SNRNP70
LUAD
0.014
high
show
ENSG00000104852
SNRNP70
BRCA
0.0012
low
show
ENSG00000104852
SNRNP70
COAD
0.0027
low
show
ENSG00000104852
SNRNP70
DLBC
0.042
high
show
ENSG00000104852
SNRNP70
PRAD
0.026
high
show
ENSG00000104852
SNRNP70
SKCM
0.03
low
show
ENSG00000104852
SNRNP70
LIHC
0.0051
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000104852
SNRNP70
LUSC
Del
3.767244
0.101782
0.365079
0.281437
ENSG00000104852
SNRNP70
LUAD
Del
2.773388
0.074694
0.319328
0.370155
ENSG00000104852
SNRNP70
LGG
Del
16.187960
0.135490
0.663961
0.500975
ENSG00000104852
SNRNP70
CESC
Del
0.847499
0.070097
0.423208
0.118644
ENSG00000104852
SNRNP70
SARC
Del
2.928609
0.177774
0.458704
0.330739
ENSG00000104852
SNRNP70
GBM
Del
12.018597
0.137161
0.527476
0.168111
ENSG00000104852
SNRNP70
PAAD
Del
0.902849
0.049425
0.294972
0.119565
ENSG00000104852
SNRNP70
UCEC
Del
1.216761
0.054635
0.461731
0.115028
ENSG00000104852
SNRNP70
OV
Del
12.975460
0.326852
0.576992
0.514680
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