Ensembl ID ENSG00000104529 Gene ID 1936 Accession 3211
Gene Symbol EEF1D Alias EF1D;EF-1D;FP1047 Full Name eukaryotic translation elongation factor 1 delta
Position 8 : 143579697 - 143599541 Length 19845 bases Strand Minus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010]

ENSG00000104529 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000104529 EEF1D 0.70 3.37e-30 KIRC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000104529 EEF1D tumour 15199388
ENSG00000104529 EEF1D non-small cell lung cancers 15359725
ENSG00000104529 EEF1D tumors 16968546
ENSG00000104529 EEF1D tumour 19434630
ENSG00000104529 EEF1D cancer 21936567
ENSG00000104529 EEF1D tumors 23227181
ENSG00000104529 EEF1D tumours 26823560
ENSG00000104529 EEF1D cancer 29342219
ENSG00000104529 EEF1D cancers 29510727
ENSG00000104529 EEF1D malignant tumor 30381327
ENSG00000104529 EEF1D tumours 9568107
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000104529 EEF1D SARC 0.032 high
ENSG00000104529 EEF1D STAD 0.047 low
ENSG00000104529 EEF1D UVM 0.0025 high
ENSG00000104529 EEF1D UCEC 0.0026 high
ENSG00000104529 EEF1D THCA 0.017 low
ENSG00000104529 EEF1D LGG 0.00019 low
ENSG00000104529 EEF1D KIRP 0.041 high
ENSG00000104529 EEF1D KICH 0.0024 high
ENSG00000104529 EEF1D THYM 0.049 low
ENSG00000104529 EEF1D BRCA 0.00064 low
ENSG00000104529 EEF1D KIRC 0.0021 high
ENSG00000104529 EEF1D PRAD 0.015 high
ENSG00000104529 EEF1D SKCM 0.016 high
ENSG00000104529 EEF1D CESC 0.02 high
ENSG00000104529 EEF1D LIHC 0.00048 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000104529 EEF1D LUSC Amp 7.853582 0.361174 0.581460 0.658683
ENSG00000104529 EEF1D LUAD Amp 6.678792 0.229682 0.626303 0.571705
ENSG00000104529 EEF1D LGG Amp 10.971340 0.160031 0.701236 0.177388
ENSG00000104529 EEF1D LGG Del 1.402326 0.046640 0.554899 0.052632
ENSG00000104529 EEF1D CESC Amp 2.979236 0.211316 0.634779 0.406780
ENSG00000104529 EEF1D READ Amp 3.595480 0.253176 0.831380 0.624242
ENSG00000104529 EEF1D COAD Amp 5.805710 0.153305 0.773983 0.556541
ENSG00000104529 EEF1D PAAD Amp 2.279447 0.134298 0.435665 0.353261
ENSG00000104529 EEF1D ESCA Amp 4.910838 0.472564 0.698473 0.673913
ENSG00000104529 EEF1D SKCM Amp 4.353501 0.226150 0.772184 0.523161
ENSG00000104529 EEF1D HNSC Amp 10.098412 0.279300 0.610063 0.720307
ENSG00000104529 EEF1D LIHC Amp 17.726068 0.393014 1.181882 0.597297
ENSG00000104529 EEF1D DLBC Amp 1.416472 0.258396 0.609102 0.291667
ENSG00000104529 EEF1D BLCA Amp 2.934567 0.237571 0.585633 0.590686
ENSG00000104529 EEF1D BRCA Amp 32.662551 0.439409 1.005428 0.572222
ENSG00000104529 EEF1D STAD Amp 4.248959 0.221865 0.590984 0.637188
ENSG00000104529 EEF1D PRAD Amp 1.071089 0.051265 0.695857 0.274390
ENSG00000104529 EEF1D UCEC Amp 1.510331 0.122922 0.735072 0.337662
ENSG00000104529 EEF1D UVM Amp 11.732583 0.660526 1.518657 0.762500
ENSG00000104529 EEF1D OV Amp 103.864949 1.525484 1.234402 0.754750