Ensembl ID
ENSG00000104356
Gene ID
10940
Accession
30129
Gene Symbol
POP1
Alias
ANXD2
Full Name
POP1 homolog, ribonuclease P/MRP subunit
Position
8 : 98117293 - 98159835
Length
42543 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs ncRNA RBP type
Canonical_RBPs
Summary
This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
ENSG00000104356 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000104356
POP1
1.07
2.43e-38
BRCA
ENSG00000104356
POP1
1.42
3.50e-44
COAD
ENSG00000104356
POP1
1.51
4.57e-14
READ
ENSG00000104356
POP1
1.36
1.36e-44
LUSC
ENSG00000104356
POP1
0.67
5.40e-14
LIHC
ENSG00000104356
POP1
1.20
9.05e-21
STAD
ENSG00000104356
POP1
0.82
1.55e-16
UCEC
ENSG00000104356
POP1
0.82
8.32e-22
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000104356
POP1
MESO
2e-04
high
show
ENSG00000104356
POP1
STAD
0.025
low
show
ENSG00000104356
POP1
UVM
0.0011
high
show
ENSG00000104356
POP1
UCEC
0.012
high
show
ENSG00000104356
POP1
ACC
0.00071
high
show
ENSG00000104356
POP1
LGG
0.0013
high
show
ENSG00000104356
POP1
READ
0.0036
low
show
ENSG00000104356
POP1
LUAD
0.0041
high
show
ENSG00000104356
POP1
BRCA
0.00015
high
show
ENSG00000104356
POP1
COAD
0.034
low
show
ENSG00000104356
POP1
UCS
0.037
high
show
ENSG00000104356
POP1
ESCA
0.01
high
show
ENSG00000104356
POP1
PRAD
0.024
high
show
ENSG00000104356
POP1
BLCA
0.029
low
show
ENSG00000104356
POP1
SKCM
0.028
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000104356
POP1
LUSC
Amp
0.631627
0.190533
0.521197
0.604790
ENSG00000104356
POP1
LUAD
Amp
5.256720
0.207552
0.634720
0.556202
ENSG00000104356
POP1
LGG
Amp
7.222111
0.123799
0.685325
0.163743
ENSG00000104356
POP1
READ
Amp
2.493068
0.211285
0.815407
0.624242
ENSG00000104356
POP1
COAD
Amp
2.189438
0.095906
0.760047
0.554324
ENSG00000104356
POP1
ESCA
Amp
1.307796
0.299193
0.625235
0.652174
ENSG00000104356
POP1
SKCM
Amp
1.020713
0.130543
0.761120
0.487738
ENSG00000104356
POP1
HNSC
Amp
1.318552
0.132148
0.574948
0.672414
ENSG00000104356
POP1
LIHC
Amp
10.957643
0.302144
1.147368
0.605405
ENSG00000104356
POP1
TGCT
Amp
0.894702
0.127110
0.525613
0.766667
ENSG00000104356
POP1
BLCA
Amp
14.358035
0.466775
0.769123
0.627451
ENSG00000104356
POP1
BRCA
Amp
29.618511
0.418751
1.020436
0.605556
ENSG00000104356
POP1
STAD
Amp
2.896627
0.191742
0.599337
0.628118
ENSG00000104356
POP1
PRAD
Amp
4.941673
0.103694
0.745102
0.319106
ENSG00000104356
POP1
UVM
Amp
9.477347
0.581109
1.507945
0.750000
ENSG00000104356
POP1
OV
Amp
14.286527
0.615218
0.930356
0.616580
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