Ensembl ID ENSG00000103549 Gene ID 9810 Accession 16867
Gene Symbol RNF40 Alias BRE1B;RBP95;STARING Full Name ring finger protein 40
Position 16 : 30761745 - 30776307 Length 14563 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

ENSG00000103549 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000103549 RNF40 0.67 1.57e-28 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000103549 RNF40 tumor 22021426
ENSG00000103549 RNF40 prostate cancer 22155569
ENSG00000103549 RNF40 tumor 22825248
ENSG00000103549 RNF40 breast cancer 24441044
ENSG00000103549 RNF40 cancer 26854224
ENSG00000103549 RNF40 tumours 27557628
ENSG00000103549 RNF40 ovarian cancer 27798111
ENSG00000103549 RNF40 tumors 28157208
ENSG00000103549 RNF40 tumor 28209164
ENSG00000103549 RNF40 cancer 28410206
ENSG00000103549 RNF40 cancer 28481029
ENSG00000103549 RNF40 cancers 29058668
ENSG00000103549 RNF40 tumor 29934362
ENSG00000103549 RNF40 Colorectal Cancer 30321325
ENSG00000103549 RNF40 tumour 30669413
ENSG00000103549 RNF40 cancer 30781493
ENSG00000103549 RNF40 colorectal cancer 31266541
ENSG00000103549 RNF40 tumor 31938414
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000103549 RNF40 SARC 0.002 high
ENSG00000103549 RNF40 STAD 0.049 low
ENSG00000103549 RNF40 CHOL 0.047 low
ENSG00000103549 RNF40 PAAD 0.03 high
ENSG00000103549 RNF40 UCEC 0.034 low
ENSG00000103549 RNF40 THCA 0.0021 high
ENSG00000103549 RNF40 ACC 0.025 low
ENSG00000103549 RNF40 LGG 0.0019 high
ENSG00000103549 RNF40 READ 0.0022 low
ENSG00000103549 RNF40 KIRP 0.037 low
ENSG00000103549 RNF40 KICH 0.0049 low
ENSG00000103549 RNF40 COAD 0.036 high
ENSG00000103549 RNF40 ESCA 0.027 low
ENSG00000103549 RNF40 BLCA 0.0039 high
ENSG00000103549 RNF40 SKCM 0.021 high
ENSG00000103549 RNF40 CESC 0.011 high
ENSG00000103549 RNF40 LIHC 0.00023 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000103549 RNF40 READ Amp 0.884377 0.134262 0.637183 0.284848
ENSG00000103549 RNF40 COAD Amp 1.060433 0.075169 0.461616 0.277162
ENSG00000103549 RNF40 UCS Amp 1.462935 0.616342 0.823517 0.357143
ENSG00000103549 RNF40 UCEC Amp 1.975312 0.132388 0.697336 0.116883