Ensembl ID
ENSG00000103549
Gene ID
9810
Accession
16867
Gene Symbol
RNF40
Alias
BRE1B;RBP95;STARING
Full Name
ring finger protein 40
Position
16 : 30761745 - 30776307
Length
14563 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
ENSG00000103549 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000103549
RNF40
0.67
1.57e-28
BRCA
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000103549
RNF40
tumor
22021426
ENSG00000103549
RNF40
prostate cancer
22155569
ENSG00000103549
RNF40
tumor
22825248
ENSG00000103549
RNF40
breast cancer
24441044
ENSG00000103549
RNF40
cancer
26854224
ENSG00000103549
RNF40
tumours
27557628
ENSG00000103549
RNF40
ovarian cancer
27798111
ENSG00000103549
RNF40
tumors
28157208
ENSG00000103549
RNF40
tumor
28209164
ENSG00000103549
RNF40
cancer
28410206
ENSG00000103549
RNF40
cancer
28481029
ENSG00000103549
RNF40
cancers
29058668
ENSG00000103549
RNF40
tumor
29934362
ENSG00000103549
RNF40
Colorectal Cancer
30321325
ENSG00000103549
RNF40
tumour
30669413
ENSG00000103549
RNF40
cancer
30781493
ENSG00000103549
RNF40
colorectal cancer
31266541
ENSG00000103549
RNF40
tumor
31938414
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000103549
RNF40
SARC
0.002
high
show
ENSG00000103549
RNF40
STAD
0.049
low
show
ENSG00000103549
RNF40
CHOL
0.047
low
show
ENSG00000103549
RNF40
PAAD
0.03
high
show
ENSG00000103549
RNF40
UCEC
0.034
low
show
ENSG00000103549
RNF40
THCA
0.0021
high
show
ENSG00000103549
RNF40
ACC
0.025
low
show
ENSG00000103549
RNF40
LGG
0.0019
high
show
ENSG00000103549
RNF40
READ
0.0022
low
show
ENSG00000103549
RNF40
KIRP
0.037
low
show
ENSG00000103549
RNF40
KICH
0.0049
low
show
ENSG00000103549
RNF40
COAD
0.036
high
show
ENSG00000103549
RNF40
ESCA
0.027
low
show
ENSG00000103549
RNF40
BLCA
0.0039
high
show
ENSG00000103549
RNF40
SKCM
0.021
high
show
ENSG00000103549
RNF40
CESC
0.011
high
show
ENSG00000103549
RNF40
LIHC
0.00023
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000103549
RNF40
READ
Amp
0.884377
0.134262
0.637183
0.284848
ENSG00000103549
RNF40
COAD
Amp
1.060433
0.075169
0.461616
0.277162
ENSG00000103549
RNF40
UCS
Amp
1.462935
0.616342
0.823517
0.357143
ENSG00000103549
RNF40
UCEC
Amp
1.975312
0.132388
0.697336
0.116883
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