Ensembl ID ENSG00000102977 Gene ID 65057 Accession 25070
Gene Symbol ACD Alias PIP1;PTOP;TPP1;TINT1 Full Name ACD shelterin complex subunit and telomerase recruitment factor
Position 16 : 67657512 - 67660810 Length 3299 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq, Jul 2008]

ENSG00000102977 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000102977 0.75 1.56e-35 KIRC
ENSG00000102977 0.81 6.32e-20 HNSC
ENSG00000102977 1.01 2.36e-23 COAD
ENSG00000102977 0.50 1.29e-11 LUSC
ENSG00000102977 0.88 2.51e-19 KIRP
ENSG00000102977 0.60 7.93e-11 LIHC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000102977 tumor 10668217
ENSG00000102977 tumour 10704256
ENSG00000102977 cancer 11107051
ENSG00000102977 breast cancer 15256112
ENSG00000102977 tumor 1879470
ENSG00000102977 colon cancer 20127035
ENSG00000102977 cancers 23771628
ENSG00000102977 cancer 23901343
ENSG00000102977 tumor 2411831
ENSG00000102977 tumour 24283919
ENSG00000102977 breast cancer 24460895
ENSG00000102977 cancer 24710486
ENSG00000102977 tumour 24965943
ENSG00000102977 AML 24995295
ENSG00000102977 tumor 25088559
ENSG00000102977 cancer 25191642
ENSG00000102977 cancers 25505254
ENSG00000102977 cancer 26345285
ENSG00000102977 Breast cancer 26488006
ENSG00000102977 tumor 26515729
ENSG00000102977 cancer 26592338
ENSG00000102977 cancers 27036224
ENSG00000102977 cancer 27064454
ENSG00000102977 cancer 27308367
ENSG00000102977 cancer 27445804
ENSG00000102977 cancer 27626481
ENSG00000102977 colon cancer 28361849
ENSG00000102977 cancer 28674677
ENSG00000102977 AML 28751774
ENSG00000102977 cancer 29118560
ENSG00000102977 breast cancer 29172540
ENSG00000102977 cancer 29246308
ENSG00000102977 triple negative breast cancer 29779135
ENSG00000102977 tumor 29878901
ENSG00000102977 colorectal cancer 29891727
ENSG00000102977 cancer 30080989
ENSG00000102977 breast cancer 30302772
ENSG00000102977 cancer 30482179
ENSG00000102977 tumor 30570508
ENSG00000102977 cancer 30647047
ENSG00000102977 cancer 31182915
ENSG00000102977 tumors 31635099
ENSG00000102977 breast cancer 31649854
ENSG00000102977 tumor 3222174
ENSG00000102977 cancer 3291772
ENSG00000102977 tumor 4025086
ENSG00000102977 Tumour 7839070
ENSG00000102977 cancer 7884248
ENSG00000102977 cancer 7919456
ENSG00000102977 tumour 9376990
ENSG00000102977 tumors 9747452
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000102977 STAD 0.047 low
ENSG00000102977 UVM 0.0087 low
ENSG00000102977 PAAD 0.00092 low
ENSG00000102977 UCEC 0.017 low
ENSG00000102977 ACC 8e-04 high
ENSG00000102977 LGG 0.006 low
ENSG00000102977 LUSC 0.012 high
ENSG00000102977 HNSC 0.006 high
ENSG00000102977 READ 0.03 low
ENSG00000102977 KIRP 0.0057 low
ENSG00000102977 KICH 0.017 low
ENSG00000102977 PCPG 0.00087 high
ENSG00000102977 THYM 0.0012 low
ENSG00000102977 COAD 0.0078 high
ENSG00000102977 DLBC 0.0083 low
ENSG00000102977 CESC 0.049 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000102977 LAML Del 2.171916 0.050448 0.627555 0.041885
ENSG00000102977 TGCT Amp 1.448869 0.152317 0.674575 0.140000
ENSG00000102977 UCEC Del 5.218856 0.090187 0.620241 0.298701
ENSG00000102977 OV Del 9.758305 0.297682 0.659159 0.794473