Ensembl ID ENSG00000102786 Gene ID 26512 Accession 14879
Gene Symbol INTS6 Alias HDB;INT6;DBI-1;DDX26;DICE1;DDX26A;Notchl2 Full Name integrator complex subunit 6
Position 13 : 51361565 - 51454264 Length 92700 bases Strand Minus strand
Status Confidence Main interacting RNAssnRNARBP type Canonical_RBPs
Summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2015]

ENSG00000102786 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000102786 INTS6 -0.6 1.14e-13 LIHC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000102786 INTS6 tumor 10467397
ENSG00000102786 INTS6 tumor 10644362
ENSG00000102786 INTS6 tumor 11071923
ENSG00000102786 INTS6 tumors 11121040
ENSG00000102786 INTS6 tumors 11536042
ENSG00000102786 INTS6 tumors 11593297
ENSG00000102786 INTS6 tumor 11904180
ENSG00000102786 INTS6 tumor 11939413
ENSG00000102786 INTS6 tumor 12527901
ENSG00000102786 INTS6 tumor 15254679
ENSG00000102786 INTS6 non-small cell lung cancer 15867213
ENSG00000102786 INTS6 prostate cancer 16007164
ENSG00000102786 INTS6 cancer 16914495
ENSG00000102786 INTS6 tumor 17310990
ENSG00000102786 INTS6 tumor 17324924
ENSG00000102786 INTS6 tumor 17626637
ENSG00000102786 INTS6 tumor 17698014
ENSG00000102786 INTS6 cancer 17895999
ENSG00000102786 INTS6 cancer 18493598
ENSG00000102786 INTS6 tumor 18828910
ENSG00000102786 INTS6 prostate cancer 19906297
ENSG00000102786 INTS6 tumors 20735817
ENSG00000102786 INTS6 tumor 20890303
ENSG00000102786 INTS6 tumor 21737453
ENSG00000102786 INTS6 cancers 21881300
ENSG00000102786 INTS6 breast cancers 22907435
ENSG00000102786 INTS6 tumor 22960363
ENSG00000102786 INTS6 tumor 23280823
ENSG00000102786 INTS6 tumor 23979421
ENSG00000102786 INTS6 tumor 24481065
ENSG00000102786 INTS6 tumor 25544772
ENSG00000102786 INTS6 Prostate Cancer 25660097
ENSG00000102786 INTS6 tumor 25686840
ENSG00000102786 INTS6 tumors 25774287
ENSG00000102786 INTS6 tumor 27308317
ENSG00000102786 INTS6 tumor 28468258
ENSG00000102786 INTS6 tumours 28899352
ENSG00000102786 INTS6 prostate cancer 29895194
ENSG00000102786 INTS6 tumor 30386928
ENSG00000102786 INTS6 tumor 7558022
ENSG00000102786 INTS6 tumors 8738604
ENSG00000102786 INTS6 tumors 9334290
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000102786 INTS6 UVM 0.0022 high
ENSG00000102786 INTS6 ACC 0.0052 high
ENSG00000102786 INTS6 READ 0.0012 high
ENSG00000102786 INTS6 PCPG 0.0049 high
ENSG00000102786 INTS6 THYM 0.025 low
ENSG00000102786 INTS6 BRCA 0.045 high
ENSG00000102786 INTS6 ESCA 0.0012 high
ENSG00000102786 INTS6 OV 0.038 high
ENSG00000102786 INTS6 KIRC 0.0031 low
ENSG00000102786 INTS6 PRAD 0.029 high
ENSG00000102786 INTS6 CESC 0.045 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000102786 INTS6 LUSC Del 3.727514 0.101566 0.384820 0.670659
ENSG00000102786 INTS6 LUAD Del 1.213930 0.058539 0.323226 0.527132
ENSG00000102786 INTS6 LGG Del 6.631840 0.085261 0.462989 0.278752
ENSG00000102786 INTS6 CESC Del 14.648623 0.213961 0.486790 0.389831
ENSG00000102786 INTS6 COAD Amp 5.112732 0.142667 0.900725 0.587583
ENSG00000102786 INTS6 SARC Del 16.594624 0.376189 0.628134 0.649805
ENSG00000102786 INTS6 GBM Del 16.872722 0.162867 0.587681 0.426343
ENSG00000102786 INTS6 THCA Del 1.956122 0.015838 0.600533 0.038076
ENSG00000102786 INTS6 HNSC Del 7.527667 0.107850 0.402973 0.394636
ENSG00000102786 INTS6 LIHC Del 24.245290 0.263347 0.611132 0.472973
ENSG00000102786 INTS6 BLCA Del 19.233494 0.244392 0.457816 0.345588
ENSG00000102786 INTS6 BRCA Del 15.447127 0.134229 0.494309 0.452778
ENSG00000102786 INTS6 PRAD Del 60.075640 0.366385 0.536286 0.436992
ENSG00000102786 INTS6 MESO Del 1.043256 0.138131 0.465176 0.471264
ENSG00000102786 INTS6 OV Del 3.973920 0.233359 0.628408 0.621762