Ensembl ID ENSG00000102699 Gene ID 143 Accession 271
Gene Symbol PARP4 Alias PH5P;p193;ARTD4;PARPL;VPARP;VWA5C;PARP-4;VAULT3;ADPRTL1 Full Name poly(ADP-ribose) polymerase family member 4
Position 13 : 24420931 - 24512778 Length 91848 bases Strand Minus strand
Status Confidence Main interacting RNAsncRNARBP type Canonical_RBPs
Summary This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq, Jul 2008]

ENSG00000102699 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000102699 PARP4 -0.7 6.64e-20 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000102699 PARP4 breast cancers 16563451
ENSG00000102699 PARP4 tumor 16773180
ENSG00000102699 PARP4 bladder cancer 17203305
ENSG00000102699 PARP4 cancer 17593814
ENSG00000102699 PARP4 cancer 18798496
ENSG00000102699 PARP4 breast cancer 24392349
ENSG00000102699 PARP4 breast cancers 26699384
ENSG00000102699 PARP4 pancreatic cancer 29940740
ENSG00000102699 PARP4 cancer 31002369
ENSG00000102699 PARP4 breast cancer 31119570
ENSG00000102699 PARP4 tumors 31203137
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000102699 PARP4 MESO 0.0058 low
ENSG00000102699 PARP4 STAD 0.036 low
ENSG00000102699 PARP4 PAAD 0.00029 high
ENSG00000102699 PARP4 UCEC 0.038 high
ENSG00000102699 PARP4 THCA 0.031 low
ENSG00000102699 PARP4 LUSC 0.03 high
ENSG00000102699 PARP4 READ 0.0018 low
ENSG00000102699 PARP4 KIRP 0.0034 low
ENSG00000102699 PARP4 KICH 0.031 high
ENSG00000102699 PARP4 UCS 0.022 high
ENSG00000102699 PARP4 OV 0.01 high
ENSG00000102699 PARP4 PRAD 0.012 high
ENSG00000102699 PARP4 BLCA 0.0031 low
ENSG00000102699 PARP4 LAML 0.0015 low
ENSG00000102699 PARP4 SKCM 0.00042 low
ENSG00000102699 PARP4 CESC 0.01 high
ENSG00000102699 PARP4 LIHC 0.032 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000102699 PARP4 LUSC Del 5.390492 0.116693 0.381400 0.682635
ENSG00000102699 PARP4 LUAD Del 7.993007 0.113510 0.344284 0.567829
ENSG00000102699 PARP4 LGG Del 2.856408 0.059514 0.448751 0.247563
ENSG00000102699 PARP4 CESC Del 5.727369 0.136524 0.481390 0.332203
ENSG00000102699 PARP4 READ Amp 4.099013 0.272581 1.064390 0.709091
ENSG00000102699 PARP4 COAD Amp 13.371975 0.247602 0.945948 0.598670
ENSG00000102699 PARP4 SARC Del 3.637154 0.192097 0.583522 0.501946
ENSG00000102699 PARP4 GBM Del 1.625831 0.063420 0.553681 0.341421
ENSG00000102699 PARP4 THCA Del 0.657763 0.008245 0.587799 0.030060
ENSG00000102699 PARP4 HNSC Del 15.807378 0.151405 0.405739 0.431034
ENSG00000102699 PARP4 LIHC Del 4.848083 0.119969 0.560843 0.367568
ENSG00000102699 PARP4 BRCA Del 2.802290 0.080096 0.460241 0.387963
ENSG00000102699 PARP4 MESO Del 1.755706 0.166753 0.489599 0.482759
ENSG00000102699 PARP4 OV Del 0.950084 0.180442 0.610686 0.575130