Ensembl ID ENSG00000102081 Gene ID 2332 Accession 3775
Gene Symbol FMR1 Alias POF;FMRP;POF1;FRAXA Full Name fragile X messenger ribonucleoprotein 1
Position X : 147911919 - 147951125 Length 39207 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]

ENSG00000102081 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000102081 FMR1 0.76 1.55e-12 KICH
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000102081 FMR1 tumour 12153140
ENSG00000102081 FMR1 testicular germ cell tumors 12629412
ENSG00000102081 FMR1 cancer 15696166
ENSG00000102081 FMR1 tumor 15761759
ENSG00000102081 FMR1 malignant tumours 17652158
ENSG00000102081 FMR1 breast cancer 17998253
ENSG00000102081 FMR1 tumour 18451862
ENSG00000102081 FMR1 neuroendocrine tumors 19097999
ENSG00000102081 FMR1 cancer 22932883
ENSG00000102081 FMR1 cancer 22984553
ENSG00000102081 FMR1 ovarian cancer 23528734
ENSG00000102081 FMR1 cancer 23948096
ENSG00000102081 FMR1 cancer 24065114
ENSG00000102081 FMR1 tumours 24092663
ENSG00000102081 FMR1 cancer 25036526
ENSG00000102081 FMR1 breast cancer 25579682
ENSG00000102081 FMR1 tumor 26425438
ENSG00000102081 FMR1 breast cancer 26703582
ENSG00000102081 FMR1 cancer 27122614
ENSG00000102081 FMR1 HNSCC 27606879
ENSG00000102081 FMR1 tumors 27683117
ENSG00000102081 FMR1 Cancers 28667565
ENSG00000102081 FMR1 breast cancer 28698590
ENSG00000102081 FMR1 cancer 28767039
ENSG00000102081 FMR1 tumour 29096020
ENSG00000102081 FMR1 tumor 29144507
ENSG00000102081 FMR1 tumor 29361610
ENSG00000102081 FMR1 tumors 29606348
ENSG00000102081 FMR1 liver cancer 29702530
ENSG00000102081 FMR1 tumor 30736860
ENSG00000102081 FMR1 cancer 31191598
ENSG00000102081 FMR1 cancer 31281495
ENSG00000102081 FMR1 cancer 31321035
ENSG00000102081 FMR1 tumour 31409605
ENSG00000102081 FMR1 lung tumor 7668289
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000102081 FMR1 MESO 0.00025 low
ENSG00000102081 FMR1 STAD 0.0065 low
ENSG00000102081 FMR1 PAAD 0.02 high
ENSG00000102081 FMR1 LGG 0.02 low
ENSG00000102081 FMR1 LUSC 0.0033 low
ENSG00000102081 FMR1 KIRP 0.0075 high
ENSG00000102081 FMR1 LUAD 0.044 low
ENSG00000102081 FMR1 COAD 0.0041 high
ENSG00000102081 FMR1 ESCA 0.0031 high
ENSG00000102081 FMR1 OV 0.0093 low
ENSG00000102081 FMR1 DLBC 0.00022 high
ENSG00000102081 FMR1 KIRC 0.00055 low
ENSG00000102081 FMR1 PRAD 0.013 high
ENSG00000102081 FMR1 BLCA 0.0089 high
ENSG00000102081 FMR1 GBM 0.05 low
ENSG00000102081 FMR1 CESC 0.0062 low
ENSG00000102081 FMR1 LIHC 0.05 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency