Ensembl ID ENSG00000102054 Gene ID 5931 Accession 9890
Gene Symbol RBBP7 Alias RbAp46 Full Name RB binding protein 7, chromatin remodeling factor
Position X : 16839283 - 16870362 Length 31080 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

ENSG00000102054 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000102054 RBBP7 0.89 8.44e-37 BRCA
ENSG00000102054 RBBP7 0.60 6.28e-14 COAD
ENSG00000102054 RBBP7 0.81 1.11e-23 LUSC
ENSG00000102054 RBBP7 -0.7 7.25e-38 PRAD
ENSG00000102054 RBBP7 -3.1 1.03e-13 PCPG
ENSG00000102054 RBBP7 0.51 3.16e-14 LIHC
ENSG00000102054 RBBP7 0.45 1.04e-12 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000102054 RBBP7 brain tumors 20920292
ENSG00000102054 RBBP7 tumor 24784717
ENSG00000102054 RBBP7 tumor 26201719
ENSG00000102054 RBBP7 tumor 30546458
ENSG00000102054 RBBP7 tumors 30637779
ENSG00000102054 RBBP7 tumor 31911655
ENSG00000102054 RBBP7 esophageal cancer 31957828
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000102054 RBBP7 UCEC 0.017 low
ENSG00000102054 RBBP7 THCA 0.00021 low
ENSG00000102054 RBBP7 ACC 0.042 low
ENSG00000102054 RBBP7 LGG 0.00026 low
ENSG00000102054 RBBP7 LUSC 0.00055 low
ENSG00000102054 RBBP7 READ 0.023 low
ENSG00000102054 RBBP7 LUAD 0.00077 high
ENSG00000102054 RBBP7 THYM 0.0066 low
ENSG00000102054 RBBP7 ESCA 0.00011 high
ENSG00000102054 RBBP7 DLBC 0.0081 low
ENSG00000102054 RBBP7 KIRC 0.039 low
ENSG00000102054 RBBP7 BLCA 0.039 low
ENSG00000102054 RBBP7 CESC 0.03 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency