Ensembl ID ENSG00000101882 Gene ID 79576 Accession 29873
Gene Symbol NKAP Alias MRXSHD Full Name NFKB activating protein
Position X : 119920672 - 119943751 Length 23080 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6. [provided by RefSeq, May 2010]

ENSG00000101882 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000101882 cancers 27694884
ENSG00000101882 breast cancer 30464609
ENSG00000101882 tumor 31277684
ENSG00000101882 gastric cancer 31305121
ENSG00000101882 colon cancer 31545474
ENSG00000101882 tumor 31555387
ENSG00000101882 cancer 31569512
ENSG00000101882 Gastric Cancer 31802890
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000101882 MESO 0.043 high
ENSG00000101882 SARC 0.00066 high
ENSG00000101882 PAAD 4e-04 low
ENSG00000101882 UCEC 0.0011 high
ENSG00000101882 ACC 0.00056 low
ENSG00000101882 LGG 0.00053 low
ENSG00000101882 LUSC 0.01 low
ENSG00000101882 HNSC 0.012 high
ENSG00000101882 KICH 0.025 high
ENSG00000101882 PCPG 0.032 high
ENSG00000101882 THYM 0.0025 high
ENSG00000101882 BRCA 0.00074 high
ENSG00000101882 ESCA 0.018 high
ENSG00000101882 OV 0.015 low
ENSG00000101882 TGCT 0.018 high
ENSG00000101882 BLCA 0.012 low
ENSG00000101882 CESC 0.004 low
ENSG00000101882 LIHC 0.0056 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency