Ensembl ID ENSG00000101868 Gene ID 5422 Accession 9173
Gene Symbol POLA1 Alias NSX;PDR;POLA;p180;VEODS Full Name DNA polymerase alpha 1, catalytic subunit
Position X : 24693909 - 24996986 Length 303078 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes the catalytic subunit of DNA polymerase, which together with a regulatory and two primase subunits, forms the DNA polymerase alpha complex. The catalytic subunit plays an essential role in the initiation of DNA replication. [provided by RefSeq, Mar 2010]

ENSG00000101868 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000101868 POLA1 0.97 4.58e-24 COAD
ENSG00000101868 POLA1 0.74 1.09e-16 LUSC
ENSG00000101868 POLA1 0.78 6.32e-14 LIHC
ENSG00000101868 POLA1 0.77 4.16e-12 STAD
ENSG00000101868 POLA1 1.19 1.33e-11 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000101868 POLA1 tumours 18813814
ENSG00000101868 POLA1 tumor 23071531
ENSG00000101868 POLA1 brain cancers 24881245
ENSG00000101868 POLA1 cancer 26795696
ENSG00000101868 POLA1 tumours 27090007
ENSG00000101868 POLA1 cancer 27182663
ENSG00000101868 POLA1 oligodendroglial tumors 27573687
ENSG00000101868 POLA1 bladder cancer 28320388
ENSG00000101868 POLA1 cancer 29416919
ENSG00000101868 POLA1 tumours 30449638
ENSG00000101868 POLA1 DLBCLs 31237044
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000101868 POLA1 MESO 0.0019 high
ENSG00000101868 POLA1 UCEC 0.017 high
ENSG00000101868 POLA1 THCA 0.036 low
ENSG00000101868 POLA1 LUSC 0.039 low
ENSG00000101868 POLA1 HNSC 0.016 low
ENSG00000101868 POLA1 READ 0.00019 low
ENSG00000101868 POLA1 THYM 0.0011 low
ENSG00000101868 POLA1 ESCA 0.013 high
ENSG00000101868 POLA1 OV 0.05 low
ENSG00000101868 POLA1 DLBC 0.038 low
ENSG00000101868 POLA1 KIRC 0.00031 low
ENSG00000101868 POLA1 PRAD 0.018 low
ENSG00000101868 POLA1 TGCT 0.036 low
ENSG00000101868 POLA1 CESC 0.004 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency