Ensembl ID
ENSG00000101391
Gene ID
51654
Accession
15880
Gene Symbol
CDK5RAP1
Alias
C42;CGI-05;HSPC167;C20orf34
Full Name
CDK5 regulatory subunit associated protein 1
Position
20 : 33358839 - 33401561
Length
42723 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs tRNA RBP type
Non-canonical_RBPs
Summary
This gene encodes a regulator of cyclin-dependent kinase 5 activity. This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013]
ENSG00000101391 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000101391
CDK5RAP1
0.40
1.86e-19
BRCA
ENSG00000101391
CDK5RAP1
1.03
3.04e-33
COAD
ENSG00000101391
CDK5RAP1
0.68
1.18e-20
KICH
ENSG00000101391
CDK5RAP1
1.20
5.10e-15
READ
ENSG00000101391
CDK5RAP1
0.54
1.50e-13
LUSC
ENSG00000101391
CDK5RAP1
0.47
1.62e-15
LIHC
ENSG00000101391
CDK5RAP1
0.65
3.07e-13
STAD
ENSG00000101391
CDK5RAP1
0.61
4.30e-22
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000101391
CDK5RAP1
tumors
19083478
ENSG00000101391
CDK5RAP1
breast cancer
25607831
ENSG00000101391
CDK5RAP1
cancer
29552116
ENSG00000101391
CDK5RAP1
brain tumors
31654853
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000101391
CDK5RAP1
MESO
0.0086
high
show
ENSG00000101391
CDK5RAP1
UVM
0.0011
high
show
ENSG00000101391
CDK5RAP1
PAAD
0.0045
low
show
ENSG00000101391
CDK5RAP1
UCEC
0.00012
high
show
ENSG00000101391
CDK5RAP1
LGG
0.00021
high
show
ENSG00000101391
CDK5RAP1
READ
0.00092
high
show
ENSG00000101391
CDK5RAP1
KICH
0.011
high
show
ENSG00000101391
CDK5RAP1
LUAD
0.031
low
show
ENSG00000101391
CDK5RAP1
PCPG
0.00028
low
show
ENSG00000101391
CDK5RAP1
THYM
1e-04
low
show
ENSG00000101391
CDK5RAP1
BRCA
0.0049
low
show
ENSG00000101391
CDK5RAP1
ESCA
0.0029
high
show
ENSG00000101391
CDK5RAP1
PRAD
0.015
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000101391
CDK5RAP1
LUSC
Amp
1.450029
0.219244
0.517567
0.588822
ENSG00000101391
CDK5RAP1
CESC
Amp
2.964236
0.210575
0.711531
0.444068
ENSG00000101391
CDK5RAP1
READ
Amp
19.108482
0.651629
1.292431
0.884848
ENSG00000101391
CDK5RAP1
COAD
Amp
31.078319
0.419720
1.151473
0.713969
ENSG00000101391
CDK5RAP1
UCS
Amp
1.656785
0.642253
0.831173
0.767857
ENSG00000101391
CDK5RAP1
HNSC
Amp
3.757593
0.182181
0.572868
0.440613
ENSG00000101391
CDK5RAP1
BLCA
Amp
2.835663
0.234539
0.576127
0.622549
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.