Ensembl ID ENSG00000101367 Gene ID 22919 Accession 6890
Gene Symbol MAPRE1 Alias EB1 Full Name microtubule associated protein RP/EB family member 1
Position 20 : 32819954 - 32850405 Length 30452 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008]

ENSG00000101367 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000101367 MAPRE1 0.45 4.16e-11 HNSC
ENSG00000101367 MAPRE1 0.35 6.26e-15 BRCA
ENSG00000101367 MAPRE1 -0.4 5.52e-27 PRAD
ENSG00000101367 MAPRE1 1.37 2.16e-19 GBM
ENSG00000101367 MAPRE1 1.30 1.25e-14 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000101367 MAPRE1 breast cancer 19967727
ENSG00000101367 MAPRE1 gastric cancer 21562367
ENSG00000101367 MAPRE1 colorectal cancer 22277732
ENSG00000101367 MAPRE1 tumor 22278908
ENSG00000101367 MAPRE1 colorectal cancer 22735596
ENSG00000101367 MAPRE1 tumor 22869553
ENSG00000101367 MAPRE1 non-small-cell lung cancer 23900080
ENSG00000101367 MAPRE1 breast cancer 24748116
ENSG00000101367 MAPRE1 colorectal cancer 26342024
ENSG00000101367 MAPRE1 breast tumor 28092269
ENSG00000101367 MAPRE1 tumor 28251929
ENSG00000101367 MAPRE1 pancreatic cancer 29228685
ENSG00000101367 MAPRE1 COAD 29295608
ENSG00000101367 MAPRE1 lung cancer 29484424
ENSG00000101367 MAPRE1 breast cancer 30368744
ENSG00000101367 MAPRE1 tumor 30658617
ENSG00000101367 MAPRE1 tumor 30963111
ENSG00000101367 MAPRE1 tumour 31712236
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000101367 MAPRE1 MESO 0.0025 high
ENSG00000101367 MAPRE1 STAD 0.031 high
ENSG00000101367 MAPRE1 CHOL 0.029 low
ENSG00000101367 MAPRE1 UVM 0.01 high
ENSG00000101367 MAPRE1 PAAD 0.04 high
ENSG00000101367 MAPRE1 UCEC 0.0029 low
ENSG00000101367 MAPRE1 THCA 0.008 high
ENSG00000101367 MAPRE1 ACC 0.0011 high
ENSG00000101367 MAPRE1 LGG 0.036 high
ENSG00000101367 MAPRE1 LUSC 0.033 high
ENSG00000101367 MAPRE1 HNSC 0.0085 high
ENSG00000101367 MAPRE1 KICH 0.00048 high
ENSG00000101367 MAPRE1 PCPG 0.033 high
ENSG00000101367 MAPRE1 THYM 0.0021 low
ENSG00000101367 MAPRE1 ESCA 0.0024 high
ENSG00000101367 MAPRE1 DLBC 0.046 low
ENSG00000101367 MAPRE1 KIRC 0.00011 low
ENSG00000101367 MAPRE1 PRAD 0.044 high
ENSG00000101367 MAPRE1 BLCA 0.002 high
ENSG00000101367 MAPRE1 GBM 0.0014 low
ENSG00000101367 MAPRE1 SKCM 0.032 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000101367 MAPRE1 LUSC Amp 1.233867 0.212114 0.528348 0.584830
ENSG00000101367 MAPRE1 CESC Amp 3.431056 0.223965 0.729207 0.440678
ENSG00000101367 MAPRE1 READ Amp 19.573267 0.665386 1.302593 0.884848
ENSG00000101367 MAPRE1 COAD Amp 31.651043 0.425266 1.154486 0.713969
ENSG00000101367 MAPRE1 UCS Amp 1.227332 0.579823 0.798832 0.767857
ENSG00000101367 MAPRE1 HNSC Amp 2.839418 0.164598 0.557630 0.440613
ENSG00000101367 MAPRE1 BLCA Amp 4.156575 0.269360 0.593660 0.627451