Ensembl ID ENSG00000101347 Gene ID 25939 Accession 15925
Gene Symbol SAMHD1 Alias DCIP;CHBL2;HDDC1;MOP-5;SBBI88;hSAMHD1 Full Name SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
Position 20 : 36890229 - 36951893 Length 61665 bases Strand Minus strand
Status Confidence Main interacting RNAsdiverseRBP type Non-canonical_RBPs
Summary This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]

ENSG00000101347 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000101347 SAMHD1 1.40 5.62e-46 KIRC
ENSG00000101347 SAMHD1 -1.7 1.22e-46 LUSC
ENSG00000101347 SAMHD1 -1.2 4.73e-31 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000101347 SAMHD1 cancers 23872947
ENSG00000101347 SAMHD1 cancer 24257155
ENSG00000101347 SAMHD1 liver cancer 24317272
ENSG00000101347 SAMHD1 cancer 24445253
ENSG00000101347 SAMHD1 cancers 24854580
ENSG00000101347 SAMHD1 tumor 25449277
ENSG00000101347 SAMHD1 cancer 25755265
ENSG00000101347 SAMHD1 cancers 26416562
ENSG00000101347 SAMHD1 cancer 26606981
ENSG00000101347 SAMHD1 cancer 26614508
ENSG00000101347 SAMHD1 colon cancer 27071091
ENSG00000101347 SAMHD1 cancer 27775344
ENSG00000101347 SAMHD1 cancer 27878450
ENSG00000101347 SAMHD1 colorectal cancer 27988520
ENSG00000101347 SAMHD1 cancer 27991919
ENSG00000101347 SAMHD1 cancer 28046007
ENSG00000101347 SAMHD1 tumor 28061811
ENSG00000101347 SAMHD1 AML 28067901
ENSG00000101347 SAMHD1 tumor 28336725
ENSG00000101347 SAMHD1 cancer 28401188
ENSG00000101347 SAMHD1 cancer 28436707
ENSG00000101347 SAMHD1 cancer 28444859
ENSG00000101347 SAMHD1 Tumor 28502830
ENSG00000101347 SAMHD1 cancer 28834754
ENSG00000101347 SAMHD1 cancer 28978134
ENSG00000101347 SAMHD1 cancers 29018771
ENSG00000101347 SAMHD1 tumor 29352181
ENSG00000101347 SAMHD1 cancers 29379009
ENSG00000101347 SAMHD1 cancer 29583030
ENSG00000101347 SAMHD1 cancer 29670289
ENSG00000101347 SAMHD1 lung cancer 29722257
ENSG00000101347 SAMHD1 cancer 29764952
ENSG00000101347 SAMHD1 tumor 29911928
ENSG00000101347 SAMHD1 cancers 29970450
ENSG00000101347 SAMHD1 AML 30016963
ENSG00000101347 SAMHD1 tumor 30039733
ENSG00000101347 SAMHD1 cancer 30054464
ENSG00000101347 SAMHD1 cancer 30305425
ENSG00000101347 SAMHD1 acute myeloid leukemia (AML) 30341277
ENSG00000101347 SAMHD1 cancer 30456372
ENSG00000101347 SAMHD1 tumors 30474474
ENSG00000101347 SAMHD1 tumor 30717368
ENSG00000101347 SAMHD1 colon cancer 30804184
ENSG00000101347 SAMHD1 Tumor 31284288
ENSG00000101347 SAMHD1 cancers 31296733
ENSG00000101347 SAMHD1 acute myeloid leukemia (AML) 31434075
ENSG00000101347 SAMHD1 cancer 31492497
ENSG00000101347 SAMHD1 cancer 31547393
ENSG00000101347 SAMHD1 AML 31778791
ENSG00000101347 SAMHD1 cancer 31914608
ENSG00000101347 SAMHD1 AML 31950591
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000101347 SAMHD1 MESO 0.0031 low
ENSG00000101347 SAMHD1 SARC 0.0013 low
ENSG00000101347 SAMHD1 UVM 0.039 high
ENSG00000101347 SAMHD1 UCEC 0.035 low
ENSG00000101347 SAMHD1 THCA 0.0017 low
ENSG00000101347 SAMHD1 ACC 0.015 low
ENSG00000101347 SAMHD1 HNSC 0.018 low
ENSG00000101347 SAMHD1 READ 0.00049 low
ENSG00000101347 SAMHD1 LUAD 0.0057 low
ENSG00000101347 SAMHD1 THYM 0.0024 high
ENSG00000101347 SAMHD1 ESCA 0.018 high
ENSG00000101347 SAMHD1 KIRC 0.0038 high
ENSG00000101347 SAMHD1 BLCA 0.023 high
ENSG00000101347 SAMHD1 LAML 0.0019 high
ENSG00000101347 SAMHD1 CESC 0.008 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000101347 SAMHD1 READ Amp 19.834098 0.674104 1.305219 0.890909
ENSG00000101347 SAMHD1 COAD Amp 31.310693 0.421990 1.141710 0.718404