Ensembl ID ENSG00000101182 Gene ID 5688 Accession 9536
Gene Symbol PSMA7 Alias C6;HSPC;RC6-1;XAPC7;HEL-S-276 Full Name proteasome 20S subunit alpha 7
Position 20 : 62136733 - 62143430 Length 6698 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9. [provided by RefSeq, Jul 2012]

ENSG00000101182 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000101182 PSMA7 0.74 3.17e-25 BRCA
ENSG00000101182 PSMA7 1.24 1.04e-22 COAD
ENSG00000101182 PSMA7 0.73 7.65e-16 KICH
ENSG00000101182 PSMA7 0.72 6.34e-19 LUSC
ENSG00000101182 PSMA7 0.93 5.64e-16 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000101182 PSMA7 prostate tumor 10554036
ENSG00000101182 PSMA7 prostate cancers 17545589
ENSG00000101182 PSMA7 tumors 17883861
ENSG00000101182 PSMA7 colorectal cancer 18202793
ENSG00000101182 PSMA7 cancer 18218048
ENSG00000101182 PSMA7 colorectal cancer 19062718
ENSG00000101182 PSMA7 prostate cancer 19082440
ENSG00000101182 PSMA7 tumor 19442227
ENSG00000101182 PSMA7 colorectal cancer 19787246
ENSG00000101182 PSMA7 prostate cancer 19893039
ENSG00000101182 PSMA7 cancer 19956906
ENSG00000101182 PSMA7 colorectal cancer 20360909
ENSG00000101182 PSMA7 AML 20808941
ENSG00000101182 PSMA7 AML 21297973
ENSG00000101182 PSMA7 tumour 21695055
ENSG00000101182 PSMA7 Cancer 21705286
ENSG00000101182 PSMA7 prostate cancer 21761314
ENSG00000101182 PSMA7 prostate cancer 22363599
ENSG00000101182 PSMA7 tumor 22426964
ENSG00000101182 PSMA7 tumor 22584585
ENSG00000101182 PSMA7 AML 22858986
ENSG00000101182 PSMA7 prostate cancer 23106877
ENSG00000101182 PSMA7 AMLs 23236401
ENSG00000101182 PSMA7 AML 23432359
ENSG00000101182 PSMA7 prostate cancer 23532770
ENSG00000101182 PSMA7 prostate cancer 23596484
ENSG00000101182 PSMA7 AML 23626719
ENSG00000101182 PSMA7 tumor 23630229
ENSG00000101182 PSMA7 cancer 23705069
ENSG00000101182 PSMA7 colorectal cancer 23839082
ENSG00000101182 PSMA7 cancer 23936220
ENSG00000101182 PSMA7 AML 24504024
ENSG00000101182 PSMA7 prostate cancers 24649157
ENSG00000101182 PSMA7 AML 24681948
ENSG00000101182 PSMA7 tumors 24830425
ENSG00000101182 PSMA7 acute myeloid leukemia (AML) 24842373
ENSG00000101182 PSMA7 AML 24932908
ENSG00000101182 PSMA7 tumor 25051111
ENSG00000101182 PSMA7 AML 25083319
ENSG00000101182 PSMA7 AML 25174404
ENSG00000101182 PSMA7 AML 25184385
ENSG00000101182 PSMA7 tumors 25482635
ENSG00000101182 PSMA7 primary cancer 25487151
ENSG00000101182 PSMA7 tumour 25683099
ENSG00000101182 PSMA7 tumor 25893296
ENSG00000101182 PSMA7 AML 26060510
ENSG00000101182 PSMA7 cancer 26221145
ENSG00000101182 PSMA7 cancer 26308666
ENSG00000101182 PSMA7 tumor 26415830
ENSG00000101182 PSMA7 AML 26444494
ENSG00000101182 PSMA7 acute myeloid leukemia (AML) 26542173
ENSG00000101182 PSMA7 minimally differentiated AML 26637397
ENSG00000101182 PSMA7 tumor 26719537
ENSG00000101182 PSMA7 tumor 26769348
ENSG00000101182 PSMA7 colon cancer 26786760
ENSG00000101182 PSMA7 tumor 26837759
ENSG00000101182 PSMA7 acute myeloid leukemia (AML) 26946078
ENSG00000101182 PSMA7 AML 27116251
ENSG00000101182 PSMA7 tumour 27117751
ENSG00000101182 PSMA7 tumor 27127882
ENSG00000101182 PSMA7 cancer 27163255
ENSG00000101182 PSMA7 AML 27355944
ENSG00000101182 PSMA7 acute myeloid leukemia (AML) 27389055
ENSG00000101182 PSMA7 breast cancer 27444552
ENSG00000101182 PSMA7 AML 27534895
ENSG00000101182 PSMA7 AML 27542251
ENSG00000101182 PSMA7 tumor 27550197
ENSG00000101182 PSMA7 tumour 27576846
ENSG00000101182 PSMA7 AML 27617961
ENSG00000101182 PSMA7 AML 27705921
ENSG00000101182 PSMA7 AML 27764807
ENSG00000101182 PSMA7 tumor 27900346
ENSG00000101182 PSMA7 cancer 27936114
ENSG00000101182 PSMA7 tumors 27966459
ENSG00000101182 PSMA7 AML 28031480
ENSG00000101182 PSMA7 AML 28213513
ENSG00000101182 PSMA7 AML 28280089
ENSG00000101182 PSMA7 tumor 28289507
ENSG00000101182 PSMA7 tumor 28405517
ENSG00000101182 PSMA7 AML 28405919
ENSG00000101182 PSMA7 AML 28429049
ENSG00000101182 PSMA7 HNSCC 28490889
ENSG00000101182 PSMA7 colorectal cancer 28523434
ENSG00000101182 PSMA7 tumor lysis syndrome 28620386
ENSG00000101182 PSMA7 cancers 28641312
ENSG00000101182 PSMA7 tumour 28825697
ENSG00000101182 PSMA7 prostate cancer 28826504
ENSG00000101182 PSMA7 Cancer 28835380
ENSG00000101182 PSMA7 AML 28870739
ENSG00000101182 PSMA7 prostate cancer 28885333
ENSG00000101182 PSMA7 tumor 28919991
ENSG00000101182 PSMA7 tumor 28920958
ENSG00000101182 PSMA7 tumor 29018448
ENSG00000101182 PSMA7 breast cancer 29137250
ENSG00000101182 PSMA7 cancer 29168461
ENSG00000101182 PSMA7 AML 29181334
ENSG00000101182 PSMA7 AML 29217774
ENSG00000101182 PSMA7 cervical cancer 29247526
ENSG00000101182 PSMA7 acute myeloid leukemia (AML) 29290617
ENSG00000101182 PSMA7 AML 29320732
ENSG00000101182 PSMA7 AML 29326930
ENSG00000101182 PSMA7 AML 29346763
ENSG00000101182 PSMA7 AML 29401684
ENSG00000101182 PSMA7 tumor 29411049
ENSG00000101182 PSMA7 AML 29439185
ENSG00000101182 PSMA7 AML 29439669
ENSG00000101182 PSMA7 AML 29441324
ENSG00000101182 PSMA7 tumor 29519936
ENSG00000101182 PSMA7 tumors 29540675
ENSG00000101182 PSMA7 AML 29599919
ENSG00000101182 PSMA7 AML 29686311
ENSG00000101182 PSMA7 tumor 29712687
ENSG00000101182 PSMA7 AML 29716633
ENSG00000101182 PSMA7 tumor 29755454
ENSG00000101182 PSMA7 AML 29773599
ENSG00000101182 PSMA7 AML 29773641
ENSG00000101182 PSMA7 AML 29868474
ENSG00000101182 PSMA7 tumours 29954368
ENSG00000101182 PSMA7 AML 29988082
ENSG00000101182 PSMA7 AML 30039919
ENSG00000101182 PSMA7 AML 30050105
ENSG00000101182 PSMA7 prostate cancer 30068710
ENSG00000101182 PSMA7 AML 30082823
ENSG00000101182 PSMA7 acute myeloid leukemia (AML) 30149601
ENSG00000101182 PSMA7 breast cancer 30154657
ENSG00000101182 PSMA7 lung cancer 30204048
ENSG00000101182 PSMA7 cancers 30254368
ENSG00000101182 PSMA7 brain tumors 30353618
ENSG00000101182 PSMA7 blood cancers 30366920
ENSG00000101182 PSMA7 prostate cancer 30444038
ENSG00000101182 PSMA7 tumors 30547048
ENSG00000101182 PSMA7 cancer 30575819
ENSG00000101182 PSMA7 AML 30582132
ENSG00000101182 PSMA7 prostate cancer 30671143
ENSG00000101182 PSMA7 tumor 30765193
ENSG00000101182 PSMA7 cancers 30829324
ENSG00000101182 PSMA7 tumor 30842549
ENSG00000101182 PSMA7 tumor 30926791
ENSG00000101182 PSMA7 acute myeloid leukemia (AML) 30986495
ENSG00000101182 PSMA7 AML 31024852
ENSG00000101182 PSMA7 tumor 31044091
ENSG00000101182 PSMA7 gastric cancer 31068280
ENSG00000101182 PSMA7 acute myeloid leukemia (AML) 31109375
ENSG00000101182 PSMA7 AML 31138698
ENSG00000101182 PSMA7 AMLs 31142733
ENSG00000101182 PSMA7 GBM 31204301
ENSG00000101182 PSMA7 AML 31221785
ENSG00000101182 PSMA7 cancer 31238049
ENSG00000101182 PSMA7 tumor 31271815
ENSG00000101182 PSMA7 cancers 31303768
ENSG00000101182 PSMA7 Cancer 31338489
ENSG00000101182 PSMA7 AMLs 31338922
ENSG00000101182 PSMA7 AML 31378673
ENSG00000101182 PSMA7 tumor 31395859
ENSG00000101182 PSMA7 AML 31448224
ENSG00000101182 PSMA7 tumor 31612044
ENSG00000101182 PSMA7 prostate cancer 31620371
ENSG00000101182 PSMA7 AML 31681706
ENSG00000101182 PSMA7 AML 31723801
ENSG00000101182 PSMA7 tumor 31727629
ENSG00000101182 PSMA7 AML 31784425
ENSG00000101182 PSMA7 prostate cancer 31809622
ENSG00000101182 PSMA7 tumors 31893998
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000101182 PSMA7 MESO 0.0015 high
ENSG00000101182 PSMA7 SARC 0.0084 high
ENSG00000101182 PSMA7 UCEC 0.021 low
ENSG00000101182 PSMA7 ACC 0.0011 high
ENSG00000101182 PSMA7 LGG 2e-04 high
ENSG00000101182 PSMA7 HNSC 0.0044 high
ENSG00000101182 PSMA7 KICH 0.005 high
ENSG00000101182 PSMA7 LUAD 0.05 high
ENSG00000101182 PSMA7 PCPG 0.016 low
ENSG00000101182 PSMA7 BRCA 0.00073 high
ENSG00000101182 PSMA7 COAD 0.016 low
ENSG00000101182 PSMA7 OV 0.0033 low
ENSG00000101182 PSMA7 DLBC 0.039 low
ENSG00000101182 PSMA7 KIRC 0.0015 high
ENSG00000101182 PSMA7 TGCT 0.021 high
ENSG00000101182 PSMA7 SKCM 6e-04 low
ENSG00000101182 PSMA7 CESC 0.045 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000101182 PSMA7 LUAD Amp 8.692392 0.258486 0.517427 0.472868
ENSG00000101182 PSMA7 READ Amp 1.361515 0.159711 1.295294 0.878788
ENSG00000101182 PSMA7 COAD Amp 2.124672 0.094829 1.164479 0.718404
ENSG00000101182 PSMA7 SARC Amp 0.837712 0.267558 0.684691 0.381323
ENSG00000101182 PSMA7 LIHC Amp 1.497360 0.134268 0.601982 0.343243
ENSG00000101182 PSMA7 BRCA Amp 18.960355 0.341362 0.695422 0.486111
ENSG00000101182 PSMA7 STAD Amp 2.274008 0.176843 0.689209 0.650794
ENSG00000101182 PSMA7 UCEC Amp 2.510037 0.142696 0.643709 0.282004
ENSG00000101182 PSMA7 OV Amp 6.177412 0.475718 0.871440 0.678756