Ensembl ID ENSG00000101146 Gene ID 8480 Accession 9828
Gene Symbol RAE1 Alias Gle2;MIG14;MRNP41;Mnrp41;dJ481F12.3;dJ800J21.1 Full Name ribonucleic acid export 1
Position 20 : 57351223 - 57379211 Length 27989 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Non-canonical_RBPs
Summary Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

ENSG00000101146 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000101146 RAE1 0.45 4.32e-11 HNSC
ENSG00000101146 RAE1 0.73 4.41e-11 BLCA
ENSG00000101146 RAE1 0.93 4.99e-50 BRCA
ENSG00000101146 RAE1 1.31 1.09e-40 COAD
ENSG00000101146 RAE1 0.50 5.91e-12 KICH
ENSG00000101146 RAE1 1.45 2.87e-20 READ
ENSG00000101146 RAE1 1.47 2.38e-84 LUSC
ENSG00000101146 RAE1 0.50 7.07e-12 LIHC
ENSG00000101146 RAE1 0.78 7.24e-12 STAD
ENSG00000101146 RAE1 0.74 2.78e-22 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000101146 RAE1 cancer 21796793
ENSG00000101146 RAE1 cancer 22740934
ENSG00000101146 RAE1 breast cancers 24395524
ENSG00000101146 RAE1 tumor 24590060
ENSG00000101146 RAE1 tumor 26731471
ENSG00000101146 RAE1 tumor 27642640
ENSG00000101146 RAE1 breast cancer 28181567
ENSG00000101146 RAE1 tumour 28276625
ENSG00000101146 RAE1 COAD 29295608
ENSG00000101146 RAE1 cancer 29399400
ENSG00000101146 RAE1 breast cancer 30814639
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000101146 RAE1 MESO 0.015 high
ENSG00000101146 RAE1 SARC 0.014 high
ENSG00000101146 RAE1 STAD 0.045 low
ENSG00000101146 RAE1 CHOL 0.048 high
ENSG00000101146 RAE1 PAAD 0.0046 low
ENSG00000101146 RAE1 UCEC 0.00044 high
ENSG00000101146 RAE1 THCA 0.025 high
ENSG00000101146 RAE1 ACC 0.00096 high
ENSG00000101146 RAE1 LUSC 0.0062 low
ENSG00000101146 RAE1 KICH 0.0044 high
ENSG00000101146 RAE1 PCPG 0.00013 high
ENSG00000101146 RAE1 THYM 0.00043 low
ENSG00000101146 RAE1 COAD 0.0079 high
ENSG00000101146 RAE1 ESCA 0.0019 high
ENSG00000101146 RAE1 DLBC 0.0087 low
ENSG00000101146 RAE1 GBM 0.046 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000101146 RAE1 LUAD Amp 6.616641 0.228592 0.500685 0.463178
ENSG00000101146 RAE1 READ Amp 1.372080 0.160188 1.293966 0.896970
ENSG00000101146 RAE1 COAD Amp 5.062741 0.141718 1.200941 0.722838
ENSG00000101146 RAE1 BRCA Amp 25.654185 0.391156 0.753288 0.492593
ENSG00000101146 RAE1 STAD Amp 4.086574 0.218550 0.719599 0.657596
ENSG00000101146 RAE1 PRAD Amp 0.767240 0.046711 0.394072 0.083333
ENSG00000101146 RAE1 UCEC Amp 0.767984 0.104531 0.598308 0.274583
ENSG00000101146 RAE1 OV Amp 3.403594 0.413538 0.844774 0.677029