Ensembl ID ENSG00000101104 Gene ID 80336 Accession 15797
Gene Symbol PABPC1L Alias EPAB;PABPC1L1;C20orf119;dJ1069P2.3 Full Name poly(A) binding protein cytoplasmic 1 like
Position 20 : 44910060 - 44958952 Length 48893 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene belongs to the polyadenylate-binding protein type-1 family of proteins. Members of this family bind to the polyA tails of mRNAs to regulate mRNA stability and translation. The mouse ortholog of this gene is required for female fertility. In human, expression of a functional protein is regulated by alternative splicing. The protein-coding splice variant for this gene is abundantly expressed in human oocytes, while a noncoding splice variant subject to nonsense-mediated decay is the predominant splice variant expressed in somatic tissues. [provided by RefSeq, Aug 2019]

ENSG00000101104 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000101104 PABPC1L 2.22 5.61e-38 KIRC
ENSG00000101104 PABPC1L 1.55 1.61e-16 HNSC
ENSG00000101104 PABPC1L 2.33 1.92e-17 BLCA
ENSG00000101104 PABPC1L 3.00 1.55e-55 COAD
ENSG00000101104 PABPC1L 3.74 1.33e-25 READ
ENSG00000101104 PABPC1L 1.76 1.27e-24 LUSC
ENSG00000101104 PABPC1L 1.13 5.22e-12 PRAD
ENSG00000101104 PABPC1L 1.68 5.81e-27 LIHC
ENSG00000101104 PABPC1L 2.51 7.25e-30 STAD
ENSG00000101104 PABPC1L 1.63 3.25e-18 UCEC
ENSG00000101104 PABPC1L 2.14 5.42e-42 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000101104 PABPC1L colorectal cancer 30867782
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000101104 PABPC1L SARC 0.014 high
ENSG00000101104 PABPC1L UVM 0.031 high
ENSG00000101104 PABPC1L PAAD 0.0019 low
ENSG00000101104 PABPC1L UCEC 0.011 high
ENSG00000101104 PABPC1L HNSC 0.024 low
ENSG00000101104 PABPC1L READ 0.036 low
ENSG00000101104 PABPC1L KIRP 0.012 high
ENSG00000101104 PABPC1L KICH 0.0027 high
ENSG00000101104 PABPC1L LUAD 0.0054 low
ENSG00000101104 PABPC1L PCPG 0.0077 high
ENSG00000101104 PABPC1L THYM 0.0019 low
ENSG00000101104 PABPC1L BRCA 0.016 low
ENSG00000101104 PABPC1L COAD 0.0017 high
ENSG00000101104 PABPC1L ESCA 0.023 high
ENSG00000101104 PABPC1L DLBC 1e-04 high
ENSG00000101104 PABPC1L PRAD 0.024 high
ENSG00000101104 PABPC1L BLCA 1e-04 low
ENSG00000101104 PABPC1L LAML 0.03 high
ENSG00000101104 PABPC1L GBM 0.033 high
ENSG00000101104 PABPC1L SKCM 0.0098 low
ENSG00000101104 PABPC1L LIHC 0.0036 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000101104 PABPC1L READ Amp 2.228860 0.199284 1.341903 0.890909
ENSG00000101104 PABPC1L COAD Amp 9.596961 0.204601 1.229184 0.725055
ENSG00000101104 PABPC1L BLCA Amp 2.233112 0.216666 0.573314 0.605392
ENSG00000101104 PABPC1L STAD Amp 3.021660 0.194494 0.713656 0.659864