Ensembl ID ENSG00000100994 Gene ID 5834 Accession 9723
Gene Symbol PYGB Alias GPBB Full Name glycogen phosphorylase B
Position 20 : 25248085 - 25298012 Length 49928 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq, Jul 2008]

ENSG00000100994 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000100994 PYGB -1.8 3.27e-16 BLCA
ENSG00000100994 PYGB 1.72 5.21e-28 KICH
ENSG00000100994 PYGB 0.91 8.27e-15 KIRP
ENSG00000100994 PYGB 1.40 5.14e-26 LIHC
ENSG00000100994 PYGB 2.32 1.04e-15 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000100994 PYGB tumor 24292700
ENSG00000100994 PYGB gastric cancer 25051373
ENSG00000100994 PYGB cancer 26882899
ENSG00000100994 PYGB cancer 29845265
ENSG00000100994 PYGB prostate cancer 30106110
ENSG00000100994 PYGB ovarian cancer 30598658
ENSG00000100994 PYGB Breast cancers 31536495
ENSG00000100994 PYGB ovarian cancer 31627092
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000100994 PYGB MESO 0.046 high
ENSG00000100994 PYGB SARC 0.043 low
ENSG00000100994 PYGB STAD 0.022 low
ENSG00000100994 PYGB CHOL 0.0013 high
ENSG00000100994 PYGB UVM 0.011 low
ENSG00000100994 PYGB PAAD 0.0014 high
ENSG00000100994 PYGB ACC 0.016 low
ENSG00000100994 PYGB LUAD 0.00012 high
ENSG00000100994 PYGB PCPG 0.0033 low
ENSG00000100994 PYGB OV 0.0036 high
ENSG00000100994 PYGB DLBC 0.0067 high
ENSG00000100994 PYGB BLCA 0.00026 high
ENSG00000100994 PYGB LAML 0.014 low
ENSG00000100994 PYGB GBM 0.045 low
ENSG00000100994 PYGB CESC 0.043 high
ENSG00000100994 PYGB LIHC 0.00036 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000100994 PYGB READ Amp 3.476988 0.249750 1.032724 0.672727
ENSG00000100994 PYGB COAD Amp 13.963245 0.254143 1.002222 0.560976