Ensembl ID ENSG00000100994 Gene ID 5834 Accession 9723
Gene Symbol PYGB Alias GPBB Full Name glycogen phosphorylase B
Position 20 : 25248085 - 25298012 Length 49928 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq, Jul 2008]

ENSG00000100994 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000100994 -1.8 3.27e-16 BLCA
ENSG00000100994 1.72 5.21e-28 KICH
ENSG00000100994 0.91 8.27e-15 KIRP
ENSG00000100994 1.40 5.14e-26 LIHC
ENSG00000100994 2.32 1.04e-15 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000100994 tumor 24292700
ENSG00000100994 gastric cancer 25051373
ENSG00000100994 cancer 26882899
ENSG00000100994 cancer 29845265
ENSG00000100994 prostate cancer 30106110
ENSG00000100994 ovarian cancer 30598658
ENSG00000100994 Breast cancers 31536495
ENSG00000100994 ovarian cancer 31627092
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000100994 MESO 0.046 high
ENSG00000100994 SARC 0.043 low
ENSG00000100994 STAD 0.022 low
ENSG00000100994 CHOL 0.0013 high
ENSG00000100994 UVM 0.011 low
ENSG00000100994 PAAD 0.0014 high
ENSG00000100994 ACC 0.016 low
ENSG00000100994 LUAD 0.00012 high
ENSG00000100994 PCPG 0.0033 low
ENSG00000100994 OV 0.0036 high
ENSG00000100994 DLBC 0.0067 high
ENSG00000100994 BLCA 0.00026 high
ENSG00000100994 LAML 0.014 low
ENSG00000100994 GBM 0.045 low
ENSG00000100994 CESC 0.043 high
ENSG00000100994 LIHC 0.00036 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000100994 READ Amp 3.476988 0.249750 1.032724 0.672727
ENSG00000100994 COAD Amp 13.963245 0.254143 1.002222 0.560976