Ensembl ID ENSG00000100941 Gene ID 5411 Accession 9162
Gene Symbol PNN Alias DRS;DRSP;SDK3;memA Full Name pinin, desmosome associated protein
Position 14 : 39175183 - 39183220 Length 8038 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Non-canonical_RBPs
Summary Enables RNA binding activity. Predicted to be involved in cell adhesion and mRNA splicing, via spliceosome. Predicted to act upstream of or within cell-cell adhesion. Located in nuclear speck. Part of catalytic step 2 spliceosome. Colocalizes with exon-exon junction complex. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000100941 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000100941 PNN 0.65 1.03e-12 COAD
ENSG00000100941 PNN 0.72 5.72e-14 LUSC
ENSG00000100941 PNN 0.59 7.47e-11 STAD
ENSG00000100941 PNN 0.63 1.32e-11 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000100941 PNN tumor 10645008
ENSG00000100941 PNN tumor 11494129
ENSG00000100941 PNN tumors 14508512
ENSG00000100941 PNN cancer 15018248
ENSG00000100941 PNN tumor 15542832
ENSG00000100941 PNN cancer 17034838
ENSG00000100941 PNN tumor 17174383
ENSG00000100941 PNN tumor 17637743
ENSG00000100941 PNN cancer 17962725
ENSG00000100941 PNN tumor 18521630
ENSG00000100941 PNN breast cancer 18541028
ENSG00000100941 PNN Tumor 20044083
ENSG00000100941 PNN Cancer 20104222
ENSG00000100941 PNN pancreatic endocrine cancer 21606156
ENSG00000100941 PNN cancer 21716177
ENSG00000100941 PNN tumor 22067671
ENSG00000100941 PNN tumours 22115752
ENSG00000100941 PNN tumor 22753024
ENSG00000100941 PNN tumor 23152886
ENSG00000100941 PNN cancer 24009881
ENSG00000100941 PNN tumors 24143235
ENSG00000100941 PNN prostate cancer 24150235
ENSG00000100941 PNN ovarian tumor 24325128
ENSG00000100941 PNN cancer 24576793
ENSG00000100941 PNN Cancer 24634003
ENSG00000100941 PNN Cancer 25044922
ENSG00000100941 PNN oral cancer 26171415
ENSG00000100941 PNN tumor 26312165
ENSG00000100941 PNN cancer 26871283
ENSG00000100941 PNN lung cancer 26872057
ENSG00000100941 PNN cancers 26900324
ENSG00000100941 PNN tumor 26956400
ENSG00000100941 PNN tumor 26975228
ENSG00000100941 PNN colorectal cancer 27107420
ENSG00000100941 PNN tumor 27175589
ENSG00000100941 PNN cancer 27575909
ENSG00000100941 PNN breast cancer 27589846
ENSG00000100941 PNN cancers 27984746
ENSG00000100941 PNN tumor 28018735
ENSG00000100941 PNN ovarian cancer 28403579
ENSG00000100941 PNN tumor 28797092
ENSG00000100941 PNN tumors 29168596
ENSG00000100941 PNN tumor 29196338
ENSG00000100941 PNN cervical cancer 29233120
ENSG00000100941 PNN brain tumors 29313301
ENSG00000100941 PNN cancer 29464864
ENSG00000100941 PNN breast tumor 29719832
ENSG00000100941 PNN Cancer 29796113
ENSG00000100941 PNN tumor 30258724
ENSG00000100941 PNN Tumor 30413686
ENSG00000100941 PNN cancer 30825026
ENSG00000100941 PNN Tumor 30955416
ENSG00000100941 PNN colorectal cancer 30973654
ENSG00000100941 PNN cancer 31067694
ENSG00000100941 PNN breast cancer 31119567
ENSG00000100941 PNN cancer 31180341
ENSG00000100941 PNN tumor 31750246
ENSG00000100941 PNN cancer 31801901
ENSG00000100941 PNN tumors 6094891
ENSG00000100941 PNN tumor 9119748
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000100941 PNN SARC 0.0049 high
ENSG00000100941 PNN PAAD 0.029 low
ENSG00000100941 PNN LGG 0.036 low
ENSG00000100941 PNN LUSC 0.012 low
ENSG00000100941 PNN HNSC 0.01 high
ENSG00000100941 PNN READ 0.014 low
ENSG00000100941 PNN KICH 0.048 high
ENSG00000100941 PNN LUAD 0.025 low
ENSG00000100941 PNN PCPG 0.00081 high
ENSG00000100941 PNN BRCA 0.0045 low
ENSG00000100941 PNN COAD 0.0086 high
ENSG00000100941 PNN UCS 0.05 low
ENSG00000100941 PNN KIRC 0.00031 high
ENSG00000100941 PNN PRAD 0.002 high
ENSG00000100941 PNN GBM 0.0077 low
ENSG00000100941 PNN SKCM 0.00052 low
ENSG00000100941 PNN LIHC 0.0017 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000100941 PNN LUAD Amp 21.370431 0.410467 0.683817 0.391473
ENSG00000100941 PNN GBM Del 3.543719 0.081246 0.602189 0.305026