Ensembl ID
ENSG00000100813
Gene ID
22985
Accession
17066
Gene Symbol
ACIN1
Alias
ACN;ACINUS;fSAP152
Full Name
apoptotic chromatin condensation inducer 1
Position
14 : 23058564 - 23095614
Length
37051 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
ENSG00000100813 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000100813
ACIN1
breast cancer
11532036
ENSG00000100813
ACIN1
tumor
11869552
ENSG00000100813
ACIN1
tumors
12425848
ENSG00000100813
ACIN1
tumor
16145213
ENSG00000100813
ACIN1
tumor
1657559
ENSG00000100813
ACIN1
tumor
17163777
ENSG00000100813
ACIN1
cancer
17273735
ENSG00000100813
ACIN1
tumor
17384984
ENSG00000100813
ACIN1
tumor
17456778
ENSG00000100813
ACIN1
tumor
17557576
ENSG00000100813
ACIN1
cancer
19308690
ENSG00000100813
ACIN1
cancer
19387494
ENSG00000100813
ACIN1
tumor
19644955
ENSG00000100813
ACIN1
tumor
21071226
ENSG00000100813
ACIN1
pancreatic cancer
22134718
ENSG00000100813
ACIN1
pancreatic tumor
22629410
ENSG00000100813
ACIN1
tumor
22824559
ENSG00000100813
ACIN1
tumor
2295051
ENSG00000100813
ACIN1
tumor
23558573
ENSG00000100813
ACIN1
cancer
23662548
ENSG00000100813
ACIN1
cancer
23817524
ENSG00000100813
ACIN1
breast cancer
23851503
ENSG00000100813
ACIN1
cancer
23896790
ENSG00000100813
ACIN1
breast cancer
24495796
ENSG00000100813
ACIN1
tumor
25238265
ENSG00000100813
ACIN1
prostate tumors
25425963
ENSG00000100813
ACIN1
malignant tumours
25587366
ENSG00000100813
ACIN1
tumors
25621263
ENSG00000100813
ACIN1
tumor
26007201
ENSG00000100813
ACIN1
cancer
26110029
ENSG00000100813
ACIN1
lung cancer
26395571
ENSG00000100813
ACIN1
tumour
26618178
ENSG00000100813
ACIN1
tumor
27371108
ENSG00000100813
ACIN1
tumors
28095874
ENSG00000100813
ACIN1
endocrine tumors
30105611
ENSG00000100813
ACIN1
Lung Cancer
30201066
ENSG00000100813
ACIN1
Tumor
30899426
ENSG00000100813
ACIN1
breast cancer
31171849
ENSG00000100813
ACIN1
tumors
3334989
ENSG00000100813
ACIN1
tumor
3712607
ENSG00000100813
ACIN1
tumour
3959155
ENSG00000100813
ACIN1
tumors of the parotid gland
4175836
ENSG00000100813
ACIN1
tumours
4376679
ENSG00000100813
ACIN1
tumor
549562
ENSG00000100813
ACIN1
tumor
6298246
ENSG00000100813
ACIN1
tumours
6439547
ENSG00000100813
ACIN1
tumour
6894926
ENSG00000100813
ACIN1
tumor
7701305
ENSG00000100813
ACIN1
tumour
9586273
ENSG00000100813
ACIN1
tumors
9728347
ENSG00000100813
ACIN1
tumours
980543
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000100813
ACIN1
SARC
0.025
high
show
ENSG00000100813
ACIN1
STAD
0.047
low
show
ENSG00000100813
ACIN1
UVM
0.0015
high
show
ENSG00000100813
ACIN1
PAAD
0.011
low
show
ENSG00000100813
ACIN1
UCEC
0.035
low
show
ENSG00000100813
ACIN1
THCA
0.018
low
show
ENSG00000100813
ACIN1
ACC
0.015
high
show
ENSG00000100813
ACIN1
LGG
0.042
low
show
ENSG00000100813
ACIN1
LUSC
0.014
low
show
ENSG00000100813
ACIN1
HNSC
0.0068
low
show
ENSG00000100813
ACIN1
KICH
0.037
high
show
ENSG00000100813
ACIN1
LUAD
0.025
low
show
ENSG00000100813
ACIN1
PCPG
0.0066
high
show
ENSG00000100813
ACIN1
THYM
0.014
low
show
ENSG00000100813
ACIN1
BRCA
0.0015
low
show
ENSG00000100813
ACIN1
COAD
0.016
high
show
ENSG00000100813
ACIN1
UCS
0.048
low
show
ENSG00000100813
ACIN1
OV
0.016
low
show
ENSG00000100813
ACIN1
KIRC
0.0025
high
show
ENSG00000100813
ACIN1
PRAD
0.017
high
show
ENSG00000100813
ACIN1
TGCT
0.018
low
show
ENSG00000100813
ACIN1
BLCA
0.021
low
show
ENSG00000100813
ACIN1
LAML
0.025
low
show
ENSG00000100813
ACIN1
LIHC
0.00018
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000100813
ACIN1
LUSC
Del
0.922822
0.068935
0.360126
0.345309
ENSG00000100813
ACIN1
LUAD
Amp
2.698195
0.163700
0.463494
0.331395
ENSG00000100813
ACIN1
ACC
Amp
1.155613
0.306544
1.181615
0.288889
ENSG00000100813
ACIN1
READ
Del
0.637830
0.068896
0.485108
0.412121
ENSG00000100813
ACIN1
GBM
Del
4.837984
0.091190
0.601286
0.299827
ENSG00000100813
ACIN1
HNSC
Del
2.170804
0.069895
0.429284
0.147510
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