Ensembl ID ENSG00000100664 Gene ID 1983 Accession 3299
Gene Symbol EIF5 Alias EIF-5;EIF-5A Full Name eukaryotic translation initiation factor 5
Position 14 : 103334192 - 103345025 Length 10834 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010]

ENSG00000100664 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000100664 EIF5 -0.7 4.43e-18 LIHC
ENSG00000100664 EIF5 -1.3 4.10e-24 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000100664 EIF5 tumour 17341295
ENSG00000100664 EIF5 breast cancer 25115391
ENSG00000100664 EIF5 cancer 27325740
ENSG00000100664 EIF5 Male Breast Cancer 27986751
ENSG00000100664 EIF5 cancer 28083147
ENSG00000100664 EIF5 cancer 28981728
ENSG00000100664 EIF5 cancer 29254159
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000100664 EIF5 MESO 0.024 low
ENSG00000100664 EIF5 PAAD 0.041 low
ENSG00000100664 EIF5 UCEC 0.011 high
ENSG00000100664 EIF5 THCA 0.00027 low
ENSG00000100664 EIF5 ACC 0.00062 high
ENSG00000100664 EIF5 READ 0.036 low
ENSG00000100664 EIF5 KIRP 0.014 low
ENSG00000100664 EIF5 KICH 0.0026 high
ENSG00000100664 EIF5 PCPG 0.03 high
ENSG00000100664 EIF5 THYM 0.0021 high
ENSG00000100664 EIF5 UCS 0.027 low
ENSG00000100664 EIF5 OV 0.0067 low
ENSG00000100664 EIF5 PRAD 0.0062 low
ENSG00000100664 EIF5 BLCA 0.014 low
ENSG00000100664 EIF5 SKCM 0.00038 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000100664 EIF5 CHOL Del 2.006740 0.312766 0.657093 0.555556
ENSG00000100664 EIF5 LUSC Amp 0.856793 0.199174 0.510255 0.315369
ENSG00000100664 EIF5 LUAD Del 1.350350 0.060007 0.316737 0.281008
ENSG00000100664 EIF5 LGG Del 4.794070 0.073654 0.529398 0.204678
ENSG00000100664 EIF5 CESC Del 2.282190 0.095420 0.473395 0.176271
ENSG00000100664 EIF5 GBM Del 0.650279 0.051037 0.575560 0.273830
ENSG00000100664 EIF5 LIHC Del 4.881316 0.120262 0.525315 0.345946
ENSG00000100664 EIF5 BRCA Del 1.881058 0.073680 0.402541 0.286111
ENSG00000100664 EIF5 STAD Del 1.537969 0.072668 0.346749 0.294785