Ensembl ID ENSG00000100603 Gene ID 22938 Accession 16696
Gene Symbol SNW1 Alias Bx42;SKIP;FUN20;Prp45;SKIIP;SKIP1;PRPF45;NCOA-62 Full Name SNW domain containing 1
Position 14 : 77717599 - 77761207 Length 43609 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Non-canonical_RBPs
Summary This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

ENSG00000100603 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000100603 SNW1 cancer 16397026
ENSG00000100603 SNW1 breast cancer 19377877
ENSG00000100603 SNW1 colon cancer 21461980
ENSG00000100603 SNW1 cancer 23696020
ENSG00000100603 SNW1 prostate cancer 23766912
ENSG00000100603 SNW1 pancreatic cancer 23908141
ENSG00000100603 SNW1 cancer 24817966
ENSG00000100603 SNW1 cancer 25257309
ENSG00000100603 SNW1 breast cancer 25450007
ENSG00000100603 SNW1 breast cancer 28733251
ENSG00000100603 SNW1 cancer 31043167
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000100603 SNW1 SARC 0.028 high
ENSG00000100603 SNW1 UVM 0.0012 high
ENSG00000100603 SNW1 PAAD 0.04 high
ENSG00000100603 SNW1 THCA 0.0039 low
ENSG00000100603 SNW1 ACC 0.00011 high
ENSG00000100603 SNW1 LUSC 0.00091 low
ENSG00000100603 SNW1 HNSC 0.0032 high
ENSG00000100603 SNW1 KIRP 7e-04 high
ENSG00000100603 SNW1 KICH 0.012 high
ENSG00000100603 SNW1 LUAD 0.0019 high
ENSG00000100603 SNW1 BRCA 0.00048 low
ENSG00000100603 SNW1 COAD 0.027 high
ENSG00000100603 SNW1 OV 0.0014 low
ENSG00000100603 SNW1 DLBC 0.0015 low
ENSG00000100603 SNW1 BLCA 0.022 high
ENSG00000100603 SNW1 LIHC 0.00024 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000100603 SNW1 CHOL Del 1.329871 0.264648 0.615290 0.527778
ENSG00000100603 SNW1 LUAD Del 0.709782 0.051195 0.314227 0.279070
ENSG00000100603 SNW1 LGG Del 11.396161 0.111642 0.545507 0.235867
ENSG00000100603 SNW1 SARC Del 0.667706 0.118797 0.566669 0.291829
ENSG00000100603 SNW1 GBM Del 1.844958 0.065672 0.598812 0.289428
ENSG00000100603 SNW1 LIHC Del 2.742039 0.095390 0.517800 0.337838
ENSG00000100603 SNW1 BRCA Del 5.292080 0.094130 0.421770 0.320370
ENSG00000100603 SNW1 KIRC Del 0.626947 0.023580 0.429059 0.429924