Ensembl ID ENSG00000100601 Gene ID 8846 Accession 17911
Gene Symbol ALKBH1 Alias ABH;ABH1;alkB;hABH;ALKBH Full Name alkB homolog 1, histone H2A dioxygenase
Position 14 : 77672404 - 77708023 Length 35620 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. [provided by RefSeq, Jul 2008]

ENSG00000100601 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000100601 ALKBH1 0.52 1.69e-14 KICH
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000100601 ALKBH1 tumours 1020066
ENSG00000100601 ALKBH1 tumors of the urinary tract 10851724
ENSG00000100601 ALKBH1 tumors 10929759
ENSG00000100601 ALKBH1 cancer 11297197
ENSG00000100601 ALKBH1 tumor 11396228
ENSG00000100601 ALKBH1 cancer 11522384
ENSG00000100601 ALKBH1 tumor 11578255
ENSG00000100601 ALKBH1 breast cancer 12029441
ENSG00000100601 ALKBH1 cancer 12418412
ENSG00000100601 ALKBH1 lung cancer 12487558
ENSG00000100601 ALKBH1 cancer 1249509
ENSG00000100601 ALKBH1 tumour 12941151
ENSG00000100601 ALKBH1 tumor 1305688
ENSG00000100601 ALKBH1 gastric cancer 13887045
ENSG00000100601 ALKBH1 Tumor 1389697
ENSG00000100601 ALKBH1 tumour 15451491
ENSG00000100601 ALKBH1 tumour 15720441
ENSG00000100601 ALKBH1 tumor 15841259
ENSG00000100601 ALKBH1 cancer 1615929
ENSG00000100601 ALKBH1 bone tumor 1664798
ENSG00000100601 ALKBH1 bladder tumors 1691319
ENSG00000100601 ALKBH1 tumor 17342245
ENSG00000100601 ALKBH1 colorectal cancer 17375356
ENSG00000100601 ALKBH1 bladder tumor 1759329
ENSG00000100601 ALKBH1 non-small cell lung cancer 18391551
ENSG00000100601 ALKBH1 tumor 1848917
ENSG00000100601 ALKBH1 cancers of the cervix 18786253
ENSG00000100601 ALKBH1 tumor 19274076
ENSG00000100601 ALKBH1 tumours 1938218
ENSG00000100601 ALKBH1 tumor 19757090
ENSG00000100601 ALKBH1 cancer 20514537
ENSG00000100601 ALKBH1 tumors 20934999
ENSG00000100601 ALKBH1 colonic tumors 2114334
ENSG00000100601 ALKBH1 tumor 2119437
ENSG00000100601 ALKBH1 tumor 21541479
ENSG00000100601 ALKBH1 tumor 22157667
ENSG00000100601 ALKBH1 tumors 2226592
ENSG00000100601 ALKBH1 tumor 22291995
ENSG00000100601 ALKBH1 lung cancer 22471454
ENSG00000100601 ALKBH1 cancer 23030724
ENSG00000100601 ALKBH1 urinary bladder cancer 23279696
ENSG00000100601 ALKBH1 tumor 23625752
ENSG00000100601 ALKBH1 tumor 2428260
ENSG00000100601 ALKBH1 tumors of the urinary bladder 2454735
ENSG00000100601 ALKBH1 tumors 2461798
ENSG00000100601 ALKBH1 cancer 24793078
ENSG00000100601 ALKBH1 tumors of the bladder 2489254
ENSG00000100601 ALKBH1 cancer 2545345
ENSG00000100601 ALKBH1 tumors 2578141
ENSG00000100601 ALKBH1 tumor 2651340
ENSG00000100601 ALKBH1 ovarian cancer 2664192
ENSG00000100601 ALKBH1 bladder tumors 2683647
ENSG00000100601 ALKBH1 tumor 27863766
ENSG00000100601 ALKBH1 tumor 2801395
ENSG00000100601 ALKBH1 prostate cancer 28231280
ENSG00000100601 ALKBH1 cancer 29107960
ENSG00000100601 ALKBH1 cancers 30017583
ENSG00000100601 ALKBH1 tumor 30392959
ENSG00000100601 ALKBH1 cancer 30405719
ENSG00000100601 ALKBH1 germ cell tumors 3044584
ENSG00000100601 ALKBH1 tumor 30517733
ENSG00000100601 ALKBH1 tumor 30613266
ENSG00000100601 ALKBH1 Gastric Cancer 30637548
ENSG00000100601 ALKBH1 tumors 3068792
ENSG00000100601 ALKBH1 tumour 3086059
ENSG00000100601 ALKBH1 tumor 30934946
ENSG00000100601 ALKBH1 tumor 31188562
ENSG00000100601 ALKBH1 cancers 31352195
ENSG00000100601 ALKBH1 cancer 31519943
ENSG00000100601 ALKBH1 pancreatic cancer 3166398
ENSG00000100601 ALKBH1 tumours 3238331
ENSG00000100601 ALKBH1 bladder tumors 3314420
ENSG00000100601 ALKBH1 tumor 3327632
ENSG00000100601 ALKBH1 tumor 3329421
ENSG00000100601 ALKBH1 tumor 3338034
ENSG00000100601 ALKBH1 tumor 3342368
ENSG00000100601 ALKBH1 cancer 3390832
ENSG00000100601 ALKBH1 tumors 3430650
ENSG00000100601 ALKBH1 bladder cancer 3433020
ENSG00000100601 ALKBH1 bladder tumors 3444167
ENSG00000100601 ALKBH1 lung cancer 3449982
ENSG00000100601 ALKBH1 lung cancer 3485586
ENSG00000100601 ALKBH1 cancer 3501142
ENSG00000100601 ALKBH1 Colorectal tumors 3516890
ENSG00000100601 ALKBH1 bladder cancer 3534312
ENSG00000100601 ALKBH1 bladder tumors 3534405
ENSG00000100601 ALKBH1 tumor 3547591
ENSG00000100601 ALKBH1 tumors 3566178
ENSG00000100601 ALKBH1 cancer 3616504
ENSG00000100601 ALKBH1 bladder tumors 3618425
ENSG00000100601 ALKBH1 tumor 3665200
ENSG00000100601 ALKBH1 bladder cancer 3672667
ENSG00000100601 ALKBH1 epithelial ovarian cancer 3756842
ENSG00000100601 ALKBH1 bladder tumors 3807094
ENSG00000100601 ALKBH1 tumors 3815366
ENSG00000100601 ALKBH1 tumour 3833308
ENSG00000100601 ALKBH1 breast cancer 3878077
ENSG00000100601 ALKBH1 tumor 3888650
ENSG00000100601 ALKBH1 tumor 3892840
ENSG00000100601 ALKBH1 tumours 4027506
ENSG00000100601 ALKBH1 metastatic cancer 5128597
ENSG00000100601 ALKBH1 malignant tumours 6031831
ENSG00000100601 ALKBH1 bladder tumors 6208400
ENSG00000100601 ALKBH1 tumours 6285497
ENSG00000100601 ALKBH1 tumor 6374223
ENSG00000100601 ALKBH1 gastric cancers 6468839
ENSG00000100601 ALKBH1 bladder tumors 6474644
ENSG00000100601 ALKBH1 bladder tumors 6492527
ENSG00000100601 ALKBH1 AML 6961727
ENSG00000100601 ALKBH1 tumor 7023226
ENSG00000100601 ALKBH1 tumor 7025414
ENSG00000100601 ALKBH1 tumors 7026511
ENSG00000100601 ALKBH1 tumours 7038622
ENSG00000100601 ALKBH1 bladder cancer 7091049
ENSG00000100601 ALKBH1 tumours 7284720
ENSG00000100601 ALKBH1 tumors 7292978
ENSG00000100601 ALKBH1 tumors 7307122
ENSG00000100601 ALKBH1 bladder tumors 7420804
ENSG00000100601 ALKBH1 tumor 7525057
ENSG00000100601 ALKBH1 tumor 7536750
ENSG00000100601 ALKBH1 bladder cancer 7591228
ENSG00000100601 ALKBH1 cancers 7905675
ENSG00000100601 ALKBH1 tumour 8130167
ENSG00000100601 ALKBH1 tumors 8155690
ENSG00000100601 ALKBH1 tumors 8508432
ENSG00000100601 ALKBH1 tumours 8586511
ENSG00000100601 ALKBH1 tumor 8632739
ENSG00000100601 ALKBH1 tumors 8690281
ENSG00000100601 ALKBH1 HNSCC 8778333
ENSG00000100601 ALKBH1 tumour 8869281
ENSG00000100601 ALKBH1 cancer 8910032
ENSG00000100601 ALKBH1 tumor 8980625
ENSG00000100601 ALKBH1 cancer 8990931
ENSG00000100601 ALKBH1 tumor 9242430
ENSG00000100601 ALKBH1 tumor 9244144
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000100601 ALKBH1 SARC 0.037 high
ENSG00000100601 ALKBH1 STAD 0.0022 high
ENSG00000100601 ALKBH1 UVM 0.049 high
ENSG00000100601 ALKBH1 PAAD 0.0047 low
ENSG00000100601 ALKBH1 UCEC 0.0038 high
ENSG00000100601 ALKBH1 LGG 0.022 low
ENSG00000100601 ALKBH1 LUSC 0.0043 low
ENSG00000100601 ALKBH1 HNSC 0.043 high
ENSG00000100601 ALKBH1 KICH 0.0087 high
ENSG00000100601 ALKBH1 THYM 0.0027 low
ENSG00000100601 ALKBH1 BRCA 0.0073 high
ENSG00000100601 ALKBH1 OV 0.0031 low
ENSG00000100601 ALKBH1 PRAD 0.025 low
ENSG00000100601 ALKBH1 GBM 0.022 low
ENSG00000100601 ALKBH1 LIHC 0.00018 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000100601 ALKBH1 CHOL Del 1.329871 0.264648 0.615290 0.527778
ENSG00000100601 ALKBH1 LUAD Del 0.677890 0.050775 0.314227 0.279070
ENSG00000100601 ALKBH1 LGG Del 11.237972 0.110798 0.545507 0.235867
ENSG00000100601 ALKBH1 SARC Del 0.636684 0.117533 0.564650 0.295720
ENSG00000100601 ALKBH1 GBM Del 1.733400 0.064546 0.598812 0.289428
ENSG00000100601 ALKBH1 LIHC Del 2.742039 0.095390 0.517800 0.337838
ENSG00000100601 ALKBH1 BRCA Del 5.138708 0.093328 0.422364 0.322222