Ensembl ID ENSG00000100410 Gene ID 84844 Accession 18000
Gene Symbol PHF5A Alias INI;Rds3;SF3B7;SAP14b;SF3b14b;bK223H9.2 Full Name PHD finger protein 5A
Position 22 : 41459717 - 41468692 Length 8976 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes. [provided by RefSeq, Jul 2008]

ENSG00000100410 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000100410 PHF5A 0.55 1.70e-12 HNSC
ENSG00000100410 PHF5A 1.08 5.87e-27 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000100410 PHF5A brain tumor 23651857
ENSG00000100410 PHF5A endometrial cancer 23675859
ENSG00000100410 PHF5A tumor 23847366
ENSG00000100410 PHF5A tumor 29566713
ENSG00000100410 PHF5A Breast Cancer 29700004
ENSG00000100410 PHF5A cancer 30766880
ENSG00000100410 PHF5A lung cancer 30932358
ENSG00000100410 PHF5A colon cancer 31054974
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000100410 PHF5A MESO 0.013 high
ENSG00000100410 PHF5A STAD 0.04 low
ENSG00000100410 PHF5A UVM 0.014 high
ENSG00000100410 PHF5A PAAD 0.0056 high
ENSG00000100410 PHF5A UCEC 0.021 low
ENSG00000100410 PHF5A LGG 0.00024 high
ENSG00000100410 PHF5A LUSC 0.0045 low
ENSG00000100410 PHF5A HNSC 0.019 high
ENSG00000100410 PHF5A READ 0.00038 low
ENSG00000100410 PHF5A KIRP 0.024 high
ENSG00000100410 PHF5A KICH 0.01 high
ENSG00000100410 PHF5A LUAD 0.00017 high
ENSG00000100410 PHF5A THYM 0.032 low
ENSG00000100410 PHF5A BRCA 0.03 low
ENSG00000100410 PHF5A UCS 0.043 low
ENSG00000100410 PHF5A OV 0.038 low
ENSG00000100410 PHF5A KIRC 0.047 high
ENSG00000100410 PHF5A PRAD 0.046 high
ENSG00000100410 PHF5A BLCA 0.049 low
ENSG00000100410 PHF5A LAML 0.00035 high
ENSG00000100410 PHF5A GBM 0.046 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000100410 PHF5A GBM Del 1.028483 0.056290 0.582681 0.339688
ENSG00000100410 PHF5A SKCM Amp 6.045629 0.268663 0.676350 0.400545
ENSG00000100410 PHF5A PCPG Del 0.827675 0.060816 0.622000 0.395062
ENSG00000100410 PHF5A BLCA Del 1.058503 0.083587 0.364337 0.450980
ENSG00000100410 PHF5A UCEC Del 1.385424 0.056844 0.552872 0.224490
ENSG00000100410 PHF5A OV Del 3.979252 0.233546 0.653447 0.811744