Ensembl ID ENSG00000100345 Gene ID 4627 Accession 7579
Gene Symbol MYH9 Alias MHA;FTNS;EPSTS;BDPLT6;DFNA17;MATINS;NMMHCA;NMHC-II-A;NMMHC-IIA Full Name myosin heavy chain 9
Position 22 : 36281280 - 36388001 Length 106722 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]

ENSG00000100345 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000100345 0.93 2.98e-16 KICH
ENSG00000100345 -0.7 1.92e-12 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000100345 AML 16276527
ENSG00000100345 breast cancer 18796164
ENSG00000100345 Gastric Cancer 21533124
ENSG00000100345 cancer 21951916
ENSG00000100345 cancer 22315094
ENSG00000100345 breast cancer 22623409
ENSG00000100345 AML 22898599
ENSG00000100345 lung cancer 23713811
ENSG00000100345 colon cancer 23737015
ENSG00000100345 breast cancer 24504141
ENSG00000100345 tumor 24670416
ENSG00000100345 cancer 25190155
ENSG00000100345 tumor 25605255
ENSG00000100345 non-small cell lung cancer 25826333
ENSG00000100345 tumors 25888090
ENSG00000100345 tumor 26369831
ENSG00000100345 AML 26448459
ENSG00000100345 cancer 26538482
ENSG00000100345 tumors 26554828
ENSG00000100345 gastric cancer 27063166
ENSG00000100345 tumor 27262074
ENSG00000100345 tumors 27437869
ENSG00000100345 tumours 27477320
ENSG00000100345 tumors 27686647
ENSG00000100345 thyroid cancer 28049826
ENSG00000100345 Cancer 28160562
ENSG00000100345 lung cancer 28546520
ENSG00000100345 colorectal cancer 28664914
ENSG00000100345 prostate cancer 28697756
ENSG00000100345 Gastric Cancer 28900514
ENSG00000100345 GBM 29435440
ENSG00000100345 cancer 29438440
ENSG00000100345 tumor 29439719
ENSG00000100345 cancer 29679756
ENSG00000100345 cancer 29934580
ENSG00000100345 cancer 30128003
ENSG00000100345 breast cancer 30258071
ENSG00000100345 HNSCC 30380422
ENSG00000100345 Gastric Cancer 30410586
ENSG00000100345 gastric cancer 30613301
ENSG00000100345 Tumor 30739906
ENSG00000100345 Colorectal Cancer 30854093
ENSG00000100345 AML 31080363
ENSG00000100345 tumor 31217907
ENSG00000100345 gastric cancer 31262330
ENSG00000100345 pancreatic cancer 31358530
ENSG00000100345 epithelial ovarian cancer 31423165
ENSG00000100345 tumor 31442208
ENSG00000100345 tumor 31594754
ENSG00000100345 tumor 31754475
ENSG00000100345 tumor 31938396
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000100345 melanoma frameshift_variant 16.83% (17/101) 2 entries
ENSG00000100345 basal cell carcinoma stop_gained 18.97% (11/58) 1 entry
ENSG00000100345 colorectal adenocarcinoma frameshift_variant 7.185% (86/1197) 2 entries
ENSG00000100345 breast ductal adenocarcinoma sequence_alteration 9.724% (60/617) 1 entry
ENSG00000100345 colorectal adenocarcinoma conservative_inframe_deletion 7.185% (86/1197) 2 entries
ENSG00000100345 melanoma conservative_inframe_deletion 16.83% (17/101) 1 entry
ENSG00000100345 breast ductal adenocarcinoma missense_variant 9.724% (60/617) 1 entry
ENSG00000100345 breast ductal adenocarcinoma conservative_inframe_deletion 9.724% (60/617) 1 entry
ENSG00000100345 basal cell carcinoma missense_variant 18.97% (11/58) 1 entry
ENSG00000100345 melanoma missense_variant 16.83% (17/101) 1 entry
ENSG00000100345 colorectal adenocarcinoma sequence_alteration 7.185% (86/1197) 1 entry
ENSG00000100345 colorectal adenocarcinoma missense_variant 7.185% (86/1197) 2 entries
ENSG00000100345 hemangioblastoma sequence_alteration 34.38% (11/32) 1 entry
ENSG00000100345 colorectal adenocarcinoma stop_gained 7.185% (86/1197) 1 entry
ENSG00000100345 gastric adenocarcinoma stop_gained 4.713% (32/679) 1 entry
ENSG00000100345 rectal adenocarcinoma missense_variant 1.31% (3/229) 1 entry
ENSG00000100345 brain glioblastoma missense_variant 0.54% (5/926) 1 entry
ENSG00000100345 nasopharyngeal squamous cell carcinoma conservative_inframe_deletion 2.395% (4/167) 1 entry
ENSG00000100345 squamous cell lung carcinoma sequence_alteration 2.493% (19/762) 1 entry
ENSG00000100345 osteosarcoma sequence_alteration 3.448% (4/116) 1 entry
ENSG00000100345 prostate carcinoma sequence_alteration 2.113% (9/426) 2 entries
ENSG00000100345 ovarian serous adenocarcinoma missense_variant 1.04% (7/673) 2 entries
ENSG00000100345 oral squamous cell carcinoma missense_variant 1.456% (3/206) 3 entries
ENSG00000100345 diffuse large B-cell lymphoma missense_variant 0.9901% (3/303) 2 entries
ENSG00000100345 esophageal squamous cell carcinoma stop_gained 2.37% (16/675) 3 entries
ENSG00000100345 hepatocellular carcinoma sequence_alteration 1.774% (16/902) 1 entry
ENSG00000100345 colon adenocarcinoma stop_gained 4.026% (31/770) 1 entry
ENSG00000100345 chronic lymphocytic leukemia missense_variant 1.239% (11/888) 1 entry
ENSG00000100345 squamous cell lung carcinoma missense_variant 2.493% (19/762) 2 entries
ENSG00000100345 hemangioblastoma missense_variant 34.38% (11/32) 1 entry
ENSG00000100345 prostate adenocarcinoma conservative_inframe_deletion 3.164% (46/1454) 1 entry
ENSG00000100345 HER2 Positive Breast Carcinoma missense_variant 9.848% (13/132) 2 entries
ENSG00000100345 bladder carcinoma missense_variant 4.324% (24/555) 1 entry
ENSG00000100345 colon adenocarcinoma missense_variant 4.026% (31/770) 6 entries
ENSG00000100345 Cervical Small Cell Carcinoma missense_variant 33.33% (2/6) 1 entry
ENSG00000100345 female breast carcinoma missense_variant 1.124% (3/267) 2 entries
ENSG00000100345 prostate carcinoma missense_variant 2.113% (9/426) 2 entries
ENSG00000100345 colon adenocarcinoma frameshift_variant 4.026% (31/770) 1 entry
ENSG00000100345 cecum adenocarcinoma missense_variant 6.818% (9/132) 1 entry
ENSG00000100345 prostate adenocarcinoma missense_variant 3.164% (46/1454) 2 entries
ENSG00000100345 head and neck squamous cell carcinoma missense_variant 0.6702% (5/746) 2 entries
ENSG00000100345 breast carcinoma sequence_alteration 1.772% (25/1411) 1 entry
ENSG00000100345 chronic lymphocytic leukemia sequence_alteration 1.239% (11/888) 1 entry
ENSG00000100345 embryonal rhabdomyosarcoma missense_variant 2.632% (2/76) 1 entry
ENSG00000100345 gastric intestinal type adenocarcinoma missense_variant 9.412% (8/85) 2 entries
ENSG00000100345 papillary renal cell carcinoma missense_variant 0.8451% (3/355) 1 entry
ENSG00000100345 skin melanoma sequence_alteration 1.965% (19/967) 3 entries
ENSG00000100345 small cell lung carcinoma frameshift_variant 0.9375% (3/320) 2 entries
ENSG00000100345 diffuse gastric adenocarcinoma missense_variant 6.329% (5/79) 3 entries
ENSG00000100345 breast carcinoma missense_variant 1.772% (25/1411) 1 entry
ENSG00000100345 nasopharyngeal squamous cell carcinoma missense_variant 2.395% (4/167) 1 entry
ENSG00000100345 angiosarcoma sequence_alteration 15.38% (2/13) 1 entry
ENSG00000100345 female breast carcinoma sequence_alteration 1.124% (3/267) 1 entry
ENSG00000100345 skin melanoma stop_gained 1.965% (19/967) 1 entry
ENSG00000100345 colon adenocarcinoma sequence_alteration 4.026% (31/770) 2 entries
ENSG00000100345 skin melanoma missense_variant 1.965% (19/967) 2 entries
ENSG00000100345 esophageal adenocarcinoma missense_variant 4.566% (20/438) 1 entry
ENSG00000100345 breast carcinoma conservative_inframe_deletion 1.772% (25/1411) 1 entry
ENSG00000100345 gastric adenocarcinoma missense_variant 4.713% (32/679) 1 entry
ENSG00000100345 pharyngeal squamous cell carcinoma missense_variant 6.452% (2/31) 2 entries
ENSG00000100345 gastric adenocarcinoma sequence_alteration 4.713% (32/679) 1 entry
ENSG00000100345 hepatocellular carcinoma missense_variant 1.774% (16/902) 1 entry
ENSG00000100345 clear cell renal carcinoma missense_variant 0.4354% (6/1378) 3 entries
ENSG00000100345 central nervous system primitive neuroectodermal neoplasm missense_variant 1.126% (5/444) 2 entries
ENSG00000100345 myelodysplastic syndrome sequence_alteration 2.703% (2/74) 1 entry
ENSG00000100345 prostate adenocarcinoma sequence_alteration 3.164% (46/1454) 1 entry
ENSG00000100345 lung adenocarcinoma stop_gained 2.489% (29/1165) 1 entry
ENSG00000100345 esophageal squamous cell carcinoma missense_variant 2.37% (16/675) 3 entries
ENSG00000100345 lung adenocarcinoma missense_variant 2.489% (29/1165) 6 entries
ENSG00000100345 esophageal squamous cell carcinoma conservative_inframe_deletion 2.37% (16/675) 1 entry
ENSG00000100345 Mantle cell lymphoma sequence_alteration 2.439% (1/41) 1 entry
ENSG00000100345 colon adenocarcinoma conservative_inframe_deletion 4.026% (31/770) 1 entry
ENSG00000100345 ovarian serous adenocarcinoma stop_gained 1.04% (7/673) 1 entry
ENSG00000100345 Pleural Mesothelioma stop_gained 0.7843% (2/255) 1 entry
ENSG00000100345 bladder transitional cell carcinoma missense_variant 0.7299% (1/137) 1 entry
ENSG00000100345 Pleural Epithelioid Mesothelioma stop_gained 0.6329% (1/158) 1 entry
ENSG00000100345 Pleural Biphasic Mesothelioma stop_gained 2.899% (2/69) 1 entry
ENSG00000100345 non-small cell lung carcinoma sequence_alteration 3.774% (2/53) 1 entry
ENSG00000100345 head and neck squamous cell carcinoma amino_acid_insertion 0.6702% (5/746) 1 entry
ENSG00000100345 brain glioblastoma sequence_alteration 0.54% (5/926) 1 entry
ENSG00000100345 large cell lung carcinoma missense_variant 5.556% (1/18) 1 entry
ENSG00000100345 clear cell renal carcinoma sequence_alteration 0.4354% (6/1378) 1 entry
ENSG00000100345 esophageal squamous cell carcinoma frameshift_variant 2.37% (16/675) 1 entry
ENSG00000100345 Invasive Breast Carcinoma frameshift_variant 8.511% (4/47) 1 entry
ENSG00000100345 Invasive Breast Carcinoma stop_gained 8.511% (4/47) 1 entry
ENSG00000100345 rectal adenocarcinoma conservative_inframe_deletion 1.31% (3/229) 1 entry
ENSG00000100345 pancreatic ductal adenocarcinoma stop_gained 3.892% (49/1259) 1 entry
ENSG00000100345 hepatocellular carcinoma frameshift_variant 1.774% (16/902) 1 entry
ENSG00000100345 Pleural Epithelioid Mesothelioma missense_variant 0.6329% (1/158) 1 entry
ENSG00000100345 Invasive Breast Carcinoma conservative_inframe_deletion 8.511% (4/47) 1 entry
ENSG00000100345 small cell lung carcinoma amino_acid_insertion 0.9375% (3/320) 1 entry
ENSG00000100345 clear cell renal carcinoma stop_gained 0.4354% (6/1378) 1 entry
ENSG00000100345 bronchoalveolar adenocarcinoma missense_variant 4.545% (1/22) 1 entry
ENSG00000100345 large cell lung carcinoma stop_gained 5.556% (1/18) 1 entry
ENSG00000100345 cecum adenocarcinoma conservative_inframe_deletion 6.818% (9/132) 1 entry
ENSG00000100345 brain glioblastoma conservative_inframe_deletion 0.54% (5/926) 1 entry
ENSG00000100345 Pleural Biphasic Mesothelioma missense_variant 2.899% (2/69) 1 entry
ENSG00000100345 Cortisol-Producing Adrenal Cortex Adenoma conservative_inframe_deletion 0.8065% (1/124) 1 entry
ENSG00000100345 Cervical Small Cell Carcinoma stop_gained 33.33% (2/6) 1 entry
ENSG00000100345 chromophobe renal cell carcinoma missense_variant 0.8696% (1/115) 1 entry
ENSG00000100345 gastric adenocarcinoma conservative_inframe_deletion 4.713% (32/679) 1 entry
ENSG00000100345 alveolar rhabdomyosarcoma missense_variant 1.695% (1/59) 1 entry
ENSG00000100345 head and neck squamous cell carcinoma stop_gained 0.6702% (5/746) 1 entry
ENSG00000100345 gastric intestinal type adenocarcinoma frameshift_variant 9.412% (8/85) 1 entry
ENSG00000100345 lung adenocarcinoma conservative_inframe_deletion 2.489% (29/1165) 1 entry
ENSG00000100345 Invasive Breast Carcinoma missense_variant 8.511% (4/47) 1 entry
ENSG00000100345 adrenal cortex carcinoma missense_variant 0.6098% (1/164) 1 entry
ENSG00000100345 ependymoma sequence_alteration 2.174% (1/46) 1 entry
ENSG00000100345 pharyngeal squamous cell carcinoma stop_gained 6.452% (2/31) 1 entry
ENSG00000100345 lung adenocarcinoma sequence_alteration 2.489% (29/1165) 1 entry
ENSG00000100345 skin melanoma frameshift_variant 1.965% (19/967) 1 entry
ENSG00000100345 renal cell carcinoma missense_variant 9.091% (1/11) 1 entry
ENSG00000100345 Pleural Mesothelioma frameshift_variant 0.7843% (2/255) 1 entry
ENSG00000100345 small cell lung carcinoma missense_variant 0.9375% (3/320) 1 entry
ENSG00000100345 Merkel cell skin cancer sequence_alteration 3.333% (1/30) 1 entry
ENSG00000100345 Pleural Mesothelioma missense_variant 0.7843% (2/255) 1 entry
ENSG00000100345 Breast Carcinoma by Gene Expression Profile missense_variant 21.05% (4/19) 1 entry
ENSG00000100345 anaplastic astrocytoma missense_variant 2.222% (1/45) 1 entry
ENSG00000100345 pulmonary blastoma missense_variant 4.167% (1/24) 1 entry
ENSG00000100345 Malignant Germ Cell Tumor missense_variant 100.0% (1/1) 1 entry
ENSG00000100345 dedifferentiated chondrosarcoma missense_variant 7.143% (1/14) 1 entry
ENSG00000100345 Pancreatic Acinar Cell Carcinoma sequence_alteration 5.0% (1/20) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000100345 UVM 0.031 low
ENSG00000100345 PAAD 0.0046 high
ENSG00000100345 THCA 0.0045 high
ENSG00000100345 ACC 0.0023 high
ENSG00000100345 HNSC 0.019 high
ENSG00000100345 READ 0.02 low
ENSG00000100345 KIRP 0.00015 high
ENSG00000100345 KICH 0.0012 high
ENSG00000100345 PCPG 0.035 low
ENSG00000100345 THYM 0.039 low
ENSG00000100345 ESCA 0.0029 low
ENSG00000100345 OV 0.027 high
ENSG00000100345 DLBC 0.028 high
ENSG00000100345 KIRC 0.0063 low
ENSG00000100345 BLCA 0.029 high
ENSG00000100345 LAML 0.023 high
ENSG00000100345 GBM 0.025 high
ENSG00000100345 SKCM 0.018 high
ENSG00000100345 LIHC 0.022 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000100345 THYM Del 0.970980 0.043130 0.436505 0.130081