Ensembl ID ENSG00000100316 Gene ID 6122 Accession 10332
Gene Symbol RPL3 Alias L3;uL3;ASC-1;TARBP-B Full Name ribosomal protein L3
Position 22 : 39312882 - 39319623 Length 6742 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

ENSG00000100316 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000100316 RPL3 0.54 5.79e-16 KIRC
ENSG00000100316 RPL3 -0.6 1.51e-13 HNSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000100316 RPL3 tumours 21407217
ENSG00000100316 RPL3 breast cancer 27926932
ENSG00000100316 RPL3 tumor 29117471
ENSG00000100316 RPL3 tumors 29530001
ENSG00000100316 RPL3 GBM 29687002
ENSG00000100316 RPL3 colon cancer 30105457
ENSG00000100316 RPL3 cancer 30213050
ENSG00000100316 RPL3 cancers 30717818
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000100316 RPL3 MESO 0.0031 low
ENSG00000100316 RPL3 SARC 0.029 high
ENSG00000100316 RPL3 PAAD 0.028 low
ENSG00000100316 RPL3 UCEC 0.0012 low
ENSG00000100316 RPL3 ACC 0.0014 high
ENSG00000100316 RPL3 READ 0.0017 low
ENSG00000100316 RPL3 KICH 0.0039 low
ENSG00000100316 RPL3 LUAD 0.0038 low
ENSG00000100316 RPL3 PCPG 0.00072 low
ENSG00000100316 RPL3 BRCA 0.0094 low
ENSG00000100316 RPL3 BLCA 0.021 low
ENSG00000100316 RPL3 LAML 0.013 high
ENSG00000100316 RPL3 GBM 0.0026 low
ENSG00000100316 RPL3 CESC 0.025 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000100316 RPL3 THYM Del 1.199597 0.051052 0.435240 0.138211
ENSG00000100316 RPL3 SKCM Amp 3.452794 0.201785 0.604792 0.384196