Ensembl ID
ENSG00000100298
Gene ID
164668
Accession
24100
Gene Symbol
APOBEC3H
Alias
A3H;ARP10;ARP-10
Full Name
apolipoprotein B mRNA editing enzyme catalytic subunit 3H
Position
22 : 39097224 - 39104067
Length
6844 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs ncRNA RBP type
Canonical_RBPs
Summary
This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
ENSG00000100298 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000100298
APOBEC3H
2.90
3.39e-91
KIRC
ENSG00000100298
APOBEC3H
1.02
1.62e-15
BRCA
ENSG00000100298
APOBEC3H
1.90
1.88e-17
KIRP
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000100298
APOBEC3H
tumor
26221327
ENSG00000100298
APOBEC3H
lung cancer
26459911
ENSG00000100298
APOBEC3H
breast cancers
26682542
ENSG00000100298
APOBEC3H
cancer
27016308
ENSG00000100298
APOBEC3H
ovarian cancer
27527602
ENSG00000100298
APOBEC3H
cancer
27551477
ENSG00000100298
APOBEC3H
cancer
27650891
ENSG00000100298
APOBEC3H
cancer
28439266
ENSG00000100298
APOBEC3H
cancer
28981865
ENSG00000100298
APOBEC3H
Cancer
29290613
ENSG00000100298
APOBEC3H
cancer
29491387
ENSG00000100298
APOBEC3H
cancer
30224517
ENSG00000100298
APOBEC3H
cancers
30233553
ENSG00000100298
APOBEC3H
cancer
30414963
ENSG00000100298
APOBEC3H
tumor
30418757
ENSG00000100298
APOBEC3H
tumours
30624727
ENSG00000100298
APOBEC3H
breast cancer
31533728
ENSG00000100298
APOBEC3H
cancer
31544853
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000100298
APOBEC3H
MESO
0.038
low
show
ENSG00000100298
APOBEC3H
SARC
0.011
low
show
ENSG00000100298
APOBEC3H
CHOL
0.023
low
show
ENSG00000100298
APOBEC3H
UVM
0.0026
high
show
ENSG00000100298
APOBEC3H
PAAD
0.042
high
show
ENSG00000100298
APOBEC3H
UCEC
0.00082
high
show
ENSG00000100298
APOBEC3H
THCA
0.0068
low
show
ENSG00000100298
APOBEC3H
ACC
0.047
low
show
ENSG00000100298
APOBEC3H
LGG
0.00025
high
show
ENSG00000100298
APOBEC3H
HNSC
0.0018
low
show
ENSG00000100298
APOBEC3H
KIRP
0.00096
high
show
ENSG00000100298
APOBEC3H
LUAD
0.0046
low
show
ENSG00000100298
APOBEC3H
THYM
0.00079
high
show
ENSG00000100298
APOBEC3H
BRCA
0.01
low
show
ENSG00000100298
APOBEC3H
COAD
0.00067
high
show
ENSG00000100298
APOBEC3H
OV
0.035
low
show
ENSG00000100298
APOBEC3H
PRAD
0.048
low
show
ENSG00000100298
APOBEC3H
LAML
0.0025
high
show
ENSG00000100298
APOBEC3H
LIHC
0.021
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000100298
APOBEC3H
THYM
Del
1.199597
0.051052
0.435240
0.138211
ENSG00000100298
APOBEC3H
SKCM
Amp
2.780365
0.183291
0.604336
0.386921
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