Ensembl ID
ENSG00000100297
Gene ID
4174
Accession
6948
Gene Symbol
MCM5
Alias
CDC46;MGORS8;P1-CDC46
Full Name
minichromosome maintenance complex component 5
Position
22 : 35400134 - 35425431
Length
25298 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008]
ENSG00000100297 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000100297
MCM5
1.05
1.25e-63
KIRC
ENSG00000100297
MCM5
1.22
2.04e-28
HNSC
ENSG00000100297
MCM5
0.72
1.89e-22
BRCA
ENSG00000100297
MCM5
1.61
5.96e-68
LUSC
ENSG00000100297
MCM5
1.85
7.92e-11
GBM
ENSG00000100297
MCM5
0.78
1.41e-16
KIRP
ENSG00000100297
MCM5
1.39
6.69e-29
LIHC
ENSG00000100297
MCM5
1.27
7.74e-19
UCEC
ENSG00000100297
MCM5
2.37
7.11e-12
CESC
ENSG00000100297
MCM5
0.64
5.11e-12
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000100297
MCM5
tumor
17936523
ENSG00000100297
MCM5
tumor
17988337
ENSG00000100297
MCM5
desmoid tumor
19130399
ENSG00000100297
MCM5
tumor
21106093
ENSG00000100297
MCM5
tumours
21478101
ENSG00000100297
MCM5
cancer
22102875
ENSG00000100297
MCM5
prostate cancer
23717685
ENSG00000100297
MCM5
tumors
23874974
ENSG00000100297
MCM5
tumor
24148819
ENSG00000100297
MCM5
cancers
24245508
ENSG00000100297
MCM5
tumor
24555920
ENSG00000100297
MCM5
breast cancer
25596707
ENSG00000100297
MCM5
gastric cancer
25916094
ENSG00000100297
MCM5
GBM
26436532
ENSG00000100297
MCM5
tumours
26725330
ENSG00000100297
MCM5
thyroid cancer
26911376
ENSG00000100297
MCM5
bladder cancer
27376135
ENSG00000100297
MCM5
cancer
28081547
ENSG00000100297
MCM5
cervical cancer
28670392
ENSG00000100297
MCM5
breast cancer
28754978
ENSG00000100297
MCM5
tumor
29151950
ENSG00000100297
MCM5
Lung Cancer
29172277
ENSG00000100297
MCM5
cervical cancer
29253764
ENSG00000100297
MCM5
AML
29286103
ENSG00000100297
MCM5
colon cancer
29534671
ENSG00000100297
MCM5
cancer
29642758
ENSG00000100297
MCM5
cancers
29721062
ENSG00000100297
MCM5
tumors
29845895
ENSG00000100297
MCM5
tumor
29871972
ENSG00000100297
MCM5
tumor
29884122
ENSG00000100297
MCM5
cervical cancer
30026832
ENSG00000100297
MCM5
tumor
30233242
ENSG00000100297
MCM5
AML
30480765
ENSG00000100297
MCM5
cancer
30618144
ENSG00000100297
MCM5
tumor
30846786
ENSG00000100297
MCM5
tumours
30943322
ENSG00000100297
MCM5
squamous cell cancer
31092424
ENSG00000100297
MCM5
tumour
31190295
ENSG00000100297
MCM5
bladder cancer
31307961
ENSG00000100297
MCM5
cancers
31323040
ENSG00000100297
MCM5
breast cancer
31579605
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000100297
MCM5
SARC
0.0034
high
show
ENSG00000100297
MCM5
STAD
0.024
low
show
ENSG00000100297
MCM5
UVM
0.01
low
show
ENSG00000100297
MCM5
PAAD
0.0071
high
show
ENSG00000100297
MCM5
THCA
0.0027
low
show
ENSG00000100297
MCM5
LUSC
0.0045
low
show
ENSG00000100297
MCM5
HNSC
0.0013
low
show
ENSG00000100297
MCM5
READ
0.00072
low
show
ENSG00000100297
MCM5
KIRP
0.0011
high
show
ENSG00000100297
MCM5
KICH
0.015
high
show
ENSG00000100297
MCM5
THYM
0.00026
low
show
ENSG00000100297
MCM5
BRCA
0.018
low
show
ENSG00000100297
MCM5
UCS
0.0058
low
show
ENSG00000100297
MCM5
ESCA
0.021
low
show
ENSG00000100297
MCM5
DLBC
0.025
low
show
ENSG00000100297
MCM5
LAML
0.0025
high
show
ENSG00000100297
MCM5
GBM
0.0074
high
show
ENSG00000100297
MCM5
SKCM
0.032
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000100297
MCM5
THYM
Del
0.805235
0.040489
0.426055
0.130081
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.