Ensembl ID ENSG00000100297 Gene ID 4174 Accession 6948
Gene Symbol MCM5 Alias CDC46;MGORS8;P1-CDC46 Full Name minichromosome maintenance complex component 5
Position 22 : 35400134 - 35425431 Length 25298 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008]

ENSG00000100297 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000100297 1.05 1.25e-63 KIRC
ENSG00000100297 1.22 2.04e-28 HNSC
ENSG00000100297 0.72 1.89e-22 BRCA
ENSG00000100297 1.61 5.96e-68 LUSC
ENSG00000100297 1.85 7.92e-11 GBM
ENSG00000100297 0.78 1.41e-16 KIRP
ENSG00000100297 1.39 6.69e-29 LIHC
ENSG00000100297 1.27 7.74e-19 UCEC
ENSG00000100297 2.37 7.11e-12 CESC
ENSG00000100297 0.64 5.11e-12 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000100297 tumor 17936523
ENSG00000100297 tumor 17988337
ENSG00000100297 desmoid tumor 19130399
ENSG00000100297 tumor 21106093
ENSG00000100297 tumours 21478101
ENSG00000100297 cancer 22102875
ENSG00000100297 prostate cancer 23717685
ENSG00000100297 tumors 23874974
ENSG00000100297 tumor 24148819
ENSG00000100297 cancers 24245508
ENSG00000100297 tumor 24555920
ENSG00000100297 breast cancer 25596707
ENSG00000100297 gastric cancer 25916094
ENSG00000100297 GBM 26436532
ENSG00000100297 tumours 26725330
ENSG00000100297 thyroid cancer 26911376
ENSG00000100297 bladder cancer 27376135
ENSG00000100297 cancer 28081547
ENSG00000100297 cervical cancer 28670392
ENSG00000100297 breast cancer 28754978
ENSG00000100297 tumor 29151950
ENSG00000100297 Lung Cancer 29172277
ENSG00000100297 cervical cancer 29253764
ENSG00000100297 AML 29286103
ENSG00000100297 colon cancer 29534671
ENSG00000100297 cancer 29642758
ENSG00000100297 cancers 29721062
ENSG00000100297 tumors 29845895
ENSG00000100297 tumor 29871972
ENSG00000100297 tumor 29884122
ENSG00000100297 cervical cancer 30026832
ENSG00000100297 tumor 30233242
ENSG00000100297 AML 30480765
ENSG00000100297 cancer 30618144
ENSG00000100297 tumor 30846786
ENSG00000100297 tumours 30943322
ENSG00000100297 squamous cell cancer 31092424
ENSG00000100297 tumour 31190295
ENSG00000100297 bladder cancer 31307961
ENSG00000100297 cancers 31323040
ENSG00000100297 breast cancer 31579605
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000100297 SARC 0.0034 high
ENSG00000100297 STAD 0.024 low
ENSG00000100297 UVM 0.01 low
ENSG00000100297 PAAD 0.0071 high
ENSG00000100297 THCA 0.0027 low
ENSG00000100297 LUSC 0.0045 low
ENSG00000100297 HNSC 0.0013 low
ENSG00000100297 READ 0.00072 low
ENSG00000100297 KIRP 0.0011 high
ENSG00000100297 KICH 0.015 high
ENSG00000100297 THYM 0.00026 low
ENSG00000100297 BRCA 0.018 low
ENSG00000100297 UCS 0.0058 low
ENSG00000100297 ESCA 0.021 low
ENSG00000100297 DLBC 0.025 low
ENSG00000100297 LAML 0.0025 high
ENSG00000100297 GBM 0.0074 high
ENSG00000100297 SKCM 0.032 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000100297 THYM Del 0.805235 0.040489 0.426055 0.130081