Ensembl ID
ENSG00000100296
Gene ID
8563
Accession
19074
Gene Symbol
THOC5
Alias
Fmip;PK1.3;fSAP79;C22orf19
Full Name
THO complex subunit 5
Position
22 : 29505879 - 29555216
Length
49338 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Non-canonical_RBPs
Summary
Predicted to enable mRNA binding activity. Involved in several processes, including monocyte differentiation; negative regulation of DNA damage checkpoint; and viral mRNA export from host cell nucleus. Located in nucleoplasm. Part of THO complex part of transcription export complex. Colocalizes with chromosome, telomeric region. Implicated in breast carcinoma. [provided by Alliance of Genome Resources, Apr 2022]
ENSG00000100296 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000100296
THOC5
0.73
3.57e-20
LUSC
ENSG00000100296
THOC5
0.74
2.88e-19
LIHC
ENSG00000100296
THOC5
0.48
5.55e-12
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000100296
THOC5
cancer
24267292
ENSG00000100296
THOC5
cancer
24410813
ENSG00000100296
THOC5
Tumor
25376987
ENSG00000100296
THOC5
tumor
26549021
ENSG00000100296
THOC5
cancer
26828015
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000100296
THOC5
STAD
0.03
low
show
ENSG00000100296
THOC5
UVM
0.0025
low
show
ENSG00000100296
THOC5
UCEC
0.021
low
show
ENSG00000100296
THOC5
LGG
0.018
high
show
ENSG00000100296
THOC5
HNSC
0.022
high
show
ENSG00000100296
THOC5
KIRP
0.0012
high
show
ENSG00000100296
THOC5
LUAD
0.037
low
show
ENSG00000100296
THOC5
THYM
0.0031
low
show
ENSG00000100296
THOC5
DLBC
0.0022
low
show
ENSG00000100296
THOC5
KIRC
0.028
high
show
ENSG00000100296
THOC5
LAML
0.026
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000100296
THOC5
THYM
Del
2.433921
0.072177
0.436920
0.162602
ENSG00000100296
THOC5
BLCA
Amp
2.519357
0.225554
0.631094
0.203431
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