Ensembl ID ENSG00000099995 Gene ID 10291 Accession 10765
Gene Symbol SF3A1 Alias PRP21;PRPF21;SAP114;SF3A120 Full Name splicing factor 3a subunit 1
Position 22 : 30331988 - 30356919 Length 24932 bases Strand Minus strand
Status Confidence Main interacting RNAssnRNARBP type Canonical_RBPs
Summary This gene encodes a subunit of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP). U2 small nuclear ribonucleoproteins play a critical role in spliceosome assembly and pre-mRNA splicing. [provided by RefSeq, Aug 2014]

ENSG00000099995 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000099995 SF3A1 -0.2 2.69e-12 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000099995 SF3A1 breast tumors 15287981
ENSG00000099995 SF3A1 AML 23645565
ENSG00000099995 SF3A1 AML 25220401
ENSG00000099995 SF3A1 Colorectal Cancer 26079486
ENSG00000099995 SF3A1 pancreatic cancer 26498691
ENSG00000099995 SF3A1 cancer 28157704
ENSG00000099995 SF3A1 breast cancer 28589855
ENSG00000099995 SF3A1 tumors 29317634
ENSG00000099995 SF3A1 cancer 30881377
ENSG00000099995 SF3A1 AML 30896832
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000099995 SF3A1 MESO 0.0051 high
ENSG00000099995 SF3A1 SARC 0.036 high
ENSG00000099995 SF3A1 UVM 0.046 low
ENSG00000099995 SF3A1 UCEC 0.0061 high
ENSG00000099995 SF3A1 ACC 0.006 high
ENSG00000099995 SF3A1 READ 0.0044 low
ENSG00000099995 SF3A1 KIRP 0.029 high
ENSG00000099995 SF3A1 KICH 0.0071 high
ENSG00000099995 SF3A1 PCPG 0.011 low
ENSG00000099995 SF3A1 ESCA 0.02 low
ENSG00000099995 SF3A1 BLCA 0.037 high
ENSG00000099995 SF3A1 LAML 0.00061 high
ENSG00000099995 SF3A1 GBM 0.0066 low
ENSG00000099995 SF3A1 LIHC 0.003 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000099995 SF3A1 THYM Del 0.970980 0.045771 0.419966 0.138211
ENSG00000099995 SF3A1 BLCA Amp 2.214309 0.216279 0.621289 0.203431
ENSG00000099995 SF3A1 UCEC Amp 2.341180 0.139530 0.679009 0.107607