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| Ensembl ID | ENSG00000099942 | Gene ID | 1399 | Accession | 2363 |
| Gene Symbol | CRKL | Alias | NA | Full Name | CRK like proto-oncogene, adaptor protein |
| Position | 22 : 20917407 - 20953747 | Length | 36341 bases | Strand | Plus strand |
| Status | Confidence | Main interacting RNAs | N.A. | RBP type | Non-canonical_RBPs |
| Summary | This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009] | ||||
ENSG00000099942 Expression In 33 Tumors
| Ensembl ID | Gene symbol | Log2 Foldchange | Pvaue | Cancer |
|---|---|---|---|---|
| ENSG00000099942 | 0.88 | 1.80e-19 | LUSC |
| Ensembl ID | Gene symbol | Cancer types | Pubmed ID |
|---|---|---|---|
| ENSG00000099942 | tumors | 19091943 | |
| ENSG00000099942 | tumor | 19168626 | |
| ENSG00000099942 | lung cancer | 19966867 | |
| ENSG00000099942 | prostate cancer | 20688158 | |
| ENSG00000099942 | tumors | 21676433 | |
| ENSG00000099942 | laryngeal cancer | 21896986 | |
| ENSG00000099942 | lung cancer | 22211192 | |
| ENSG00000099942 | hematopoietic tumors | 22244889 | |
| ENSG00000099942 | gastric cancer | 22383989 | |
| ENSG00000099942 | non-small cell lung cancers | 22586683 | |
| ENSG00000099942 | gastric cancer | 22591714 | |
| ENSG00000099942 | small cell lung cancer | 22736441 | |
| ENSG00000099942 | non-small cell lung cancer | 22753141 | |
| ENSG00000099942 | tumor | 23318429 | |
| ENSG00000099942 | cancer | 23397142 | |
| ENSG00000099942 | breast cancer | 23686806 | |
| ENSG00000099942 | gastric cancer | 24055140 | |
| ENSG00000099942 | cancer | 24110284 | |
| ENSG00000099942 | bladder cancer | 24375195 | |
| ENSG00000099942 | colon cancer | 24389200 | |
| ENSG00000099942 | lung cancer | 24664993 | |
| ENSG00000099942 | metastatic cancer | 24805778 | |
| ENSG00000099942 | breast cancer | 24913448 | |
| ENSG00000099942 | lung cancers | 24939008 | |
| ENSG00000099942 | pancreatic cancer | 25318601 | |
| ENSG00000099942 | breast cancer | 25405387 | |
| ENSG00000099942 | tumor | 25531052 | |
| ENSG00000099942 | cancer | 25540073 | |
| ENSG00000099942 | tumour | 25661331 | |
| ENSG00000099942 | pancreatic cancer | 25897431 | |
| ENSG00000099942 | tumor | 25960220 | |
| ENSG00000099942 | cancer | 26079153 | |
| ENSG00000099942 | tumor | 26728244 | |
| ENSG00000099942 | cancer | 26756996 | |
| ENSG00000099942 | lung cancer | 26758680 | |
| ENSG00000099942 | cervical cancer | 27133071 | |
| ENSG00000099942 | cancer | 27686861 | |
| ENSG00000099942 | tumor | 27846244 | |
| ENSG00000099942 | tumor | 28029654 | |
| ENSG00000099942 | tumor | 28123521 | |
| ENSG00000099942 | gastric cancer | 28239297 | |
| ENSG00000099942 | gastric cancer | 28255248 | |
| ENSG00000099942 | breast cancer | 28392847 | |
| ENSG00000099942 | cancer | 28436261 | |
| ENSG00000099942 | acute myeloid leukemia (AML) | 28549153 | |
| ENSG00000099942 | tumor | 28558797 | |
| ENSG00000099942 | Cancer | 28723560 | |
| ENSG00000099942 | cancer | 28887306 | |
| ENSG00000099942 | breast cancer | 29155146 | |
| ENSG00000099942 | Cervical Cancer | 29295725 | |
| ENSG00000099942 | lung cancer | 29344280 | |
| ENSG00000099942 | ovarian cancer | 29344361 | |
| ENSG00000099942 | tumor | 29403024 | |
| ENSG00000099942 | tumor | 29409051 | |
| ENSG00000099942 | cancer | 30015845 | |
| ENSG00000099942 | Tumor | 30480076 | |
| ENSG00000099942 | ER+ breast cancers | 30914635 | |
| ENSG00000099942 | bladder cancer | 30964165 | |
| ENSG00000099942 | cervical tumor | 31133010 | |
| ENSG00000099942 | breast cancer | 31323992 | |
| ENSG00000099942 | tumor | 31610796 | |
| ENSG00000099942 | Colorectal Cancer | 31755734 | |
| ENSG00000099942 | tumors | 31913340 |
| Ensembl ID | Gene symbol | Disease/phenotype | Mutation type | Mutated / Total samples | Literature |
|---|
| Ensembl ID | Gene symbol | Cancer | P-value | Which worse | show |
|---|---|---|---|---|---|
| ENSG00000099942 | SARC | 0.0013 | high | ||
| ENSG00000099942 | STAD | 0.032 | low | ||
| ENSG00000099942 | UVM | 0.039 | low | ||
| ENSG00000099942 | UCEC | 0.02 | high | ||
| ENSG00000099942 | ACC | 0.0046 | high | ||
| ENSG00000099942 | LUSC | 0.036 | low | ||
| ENSG00000099942 | READ | 0.0011 | low | ||
| ENSG00000099942 | KIRP | 9e-04 | high | ||
| ENSG00000099942 | KICH | 0.00027 | high | ||
| ENSG00000099942 | LUAD | 0.019 | high | ||
| ENSG00000099942 | PCPG | 0.0028 | low | ||
| ENSG00000099942 | THYM | 0.0089 | low | ||
| ENSG00000099942 | ESCA | 0.017 | low | ||
| ENSG00000099942 | KIRC | 0.0069 | low | ||
| ENSG00000099942 | PRAD | 0.028 | high | ||
| ENSG00000099942 | BLCA | 0.002 | low | ||
| ENSG00000099942 | LAML | 0.032 | high | ||
| ENSG00000099942 | GBM | 0.013 | low | ||
| ENSG00000099942 | SKCM | 0.011 | high | ||
| ENSG00000099942 | LIHC | 0.022 | high |
| Ensembl ID | Gene symbol | Cancer | CNV type | -log10(q-value) | G-score | average amplitude | frequency |
|---|